| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the hydroxyzine-1524 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTC1 | actin, alpha, cardiac muscle 1 |
| ADAM17 | ADAM metallopeptidase domain 17 |
| ADAMTS13 | ADAM metallopeptidase with thrombospondin type 1 motif, 13 |
| AHNAK2 | AHNAK nucleoprotein 2 |
| AK2 | adenylate kinase 2 |
| APOC1 | apolipoprotein C-I |
| ARHGAP33 | Rho GTPase activating protein 33 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ASIC3 | acid sensing (proton gated) ion channel 3 |
| ATF6B | activating transcription factor 6 beta |
| BMP5 | bone morphogenetic protein 5 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CD200 | CD200 molecule |
| CDH8 | cadherin 8, type 2 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 |
| CEP97 | centrosomal protein 97kDa |
| CERS4 | ceramide synthase 4 |
| CNTNAP2 | contactin associated protein-like 2 |
| COL4A6 | collagen, type IV, alpha 6 |
| COL8A1 | collagen, type VIII, alpha 1 |
| COLEC10 | collectin sub-family member 10 (C-type lectin) |
| DBF4B | DBF4 zinc finger B |
| DFNB31 | deafness, autosomal recessive 31 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DOCK4 | dedicator of cytokinesis 4 |
| DOCK5 | dedicator of cytokinesis 5 |
| EFNB3 | ephrin-B3 |
| EGFR | epidermal growth factor receptor |
| EHBP1L1 | EH domain binding protein 1-like 1 |
| ERCC2 | excision repair cross-complementation group 2 |
| EZR | ezrin |
| FBXO9 | F-box protein 9 |
| FKBP8 | FK506 binding protein 8, 38kDa |
| FUT4 | fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GK2 | glycerol kinase 2 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GSDMD | gasdermin D |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HBS1L | HBS1-like translational GTPase |
| HNMT | histamine N-methyltransferase |
| HOMER3 | homer scaffolding protein 3 |
| HOXC4 | homeobox C4 |
| HSF2 | heat shock transcription factor 2 |
| ITSN1 | intersectin 1 (SH3 domain protein) |
| KCNK2 | potassium channel, two pore domain subfamily K, member 2 |
| KIAA0319L | KIAA0319-like |
| KRT24 | keratin 24, type I |
| KRT83 | keratin 83, type II |
| LTB | lymphotoxin beta (TNF superfamily, member 3) |
| LTB4R | leukotriene B4 receptor |
| MAP4 | microtubule-associated protein 4 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MPPE1 | metallophosphoesterase 1 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MTA1 | metastasis associated 1 |
| MYH6 | myosin, heavy chain 6, cardiac muscle, alpha |
| MYL10 | myosin, light chain 10, regulatory |
| NPTX2 | neuronal pentraxin II |
| NPY6R | neuropeptide Y receptor Y6 (pseudogene) |
| NRP2 | neuropilin 2 |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PCDH1 | protocadherin 1 |
| PLK3 | polo-like kinase 3 |
| PRPH | peripherin |
| PRSS53 | protease, serine, 53 |
| RAD52 | RAD52 homolog (S. cerevisiae) |
| RFPL1S | RFPL1 antisense RNA 1 |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| S100A8 | S100 calcium binding protein A8 |
| SAFB | scaffold attachment factor B |
| SCAI | suppressor of cancer cell invasion |
| SIRT5 | sirtuin 5 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 |
| SMIM14 | small integral membrane protein 14 |
| SPRR1B | small proline-rich protein 1B |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| SYNJ2 | synaptojanin 2 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TMEM242 | transmembrane protein 242 |
| TMPRSS15 | transmembrane protease, serine 15 |
| TNS1 | tensin 1 |
| TSPAN9 | tetraspanin 9 |
| TUBA3C | tubulin, alpha 3c |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| VASH2 | vasohibin 2 |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| VWA5A | von Willebrand factor A domain containing 5A |
| WNK1 | WNK lysine deficient protein kinase 1 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF287 | zinc finger protein 287 |
| ZNF473 | zinc finger protein 473 |
| ZNF79 | zinc finger protein 79 |
| Symbol | Name |
|---|---|
| ABLIM3 | actin binding LIM protein family, member 3 |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ARMC4 | armadillo repeat containing 4 |
| ART1 | ADP-ribosyltransferase 1 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C3 | complement component 3 |
| CAPN15 | calpain 15 |
| CCDC121 | coiled-coil domain containing 121 |
| CCDC186 | coiled-coil domain containing 186 |
| CCDC69 | coiled-coil domain containing 69 |
| CCDC88C | coiled-coil domain containing 88C |
| CD83 | CD83 molecule |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CTSF | cathepsin F |
| DCLRE1A | DNA cross-link repair 1A |
| ENO3 | enolase 3 (beta, muscle) |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| F2R | coagulation factor II (thrombin) receptor |
| FAM155B | family with sequence similarity 155, member B |
| FBXO31 | F-box protein 31 |
| FMOD | fibromodulin |
| FOSL1 | FOS-like antigen 1 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| GMPR | guanosine monophosphate reductase |
| HIRA | histone cell cycle regulator |
| HIST1H2BJ | histone cluster 1, H2bj |
| HOOK1 | hook microtubule-tethering protein 1 |
| HOXC10 | homeobox C10 |
| HYI | hydroxypyruvate isomerase (putative) |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| INO80D | INO80 complex subunit D |
| IRF1 | interferon regulatory factor 1 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITGA10 | integrin, alpha 10 |
| KLF2 | Kruppel-like factor 2 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LIN7A | lin-7 homolog A (C. elegans) |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| MICALL2 | MICAL-like 2 |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MSI1 | musashi RNA-binding protein 1 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MVP | major vault protein |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NCS1 | neuronal calcium sensor 1 |
| NEK11 | NIMA-related kinase 11 |
| NIPAL2 | NIPA-like domain containing 2 |
| NKX3-2 | NK3 homeobox 2 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NT5C | 5', 3'-nucleotidase, cytosolic |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PRR14L | proline rich 14-like |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PRSS22 | protease, serine, 22 |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| RAB30 | RAB30, member RAS oncogene family |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SFT2D2 | SFT2 domain containing 2 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SSBP3 | single stranded DNA binding protein 3 |
| TCTN2 | tectonic family member 2 |
| TESC | tescalcin |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| THBS3 | thrombospondin 3 |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TMEM120B | transmembrane protein 120B |
| TMEM121 | transmembrane protein 121 |
| TMEM180 | transmembrane protein 180 |
| TMEM184C | transmembrane protein 184C |
| TRAIP | TRAF interacting protein |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VEGFC | vascular endothelial growth factor C |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| ZNF141 | zinc finger protein 141 |
| ZNF211 | zinc finger protein 211 |
| ZNF428 | zinc finger protein 428 |
| ZNF484 | zinc finger protein 484 |
| ZNF76 | zinc finger protein 76 |
| ZNF770 | zinc finger protein 770 |
| ZNF8 | zinc finger protein 8 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |