hydroxyzine-1524 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

196 genes differentially expressed following the hydroxyzine-1524 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTC1 actin, alpha, cardiac muscle 1
ADAM17 ADAM metallopeptidase domain 17
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
AHNAK2 AHNAK nucleoprotein 2
AK2 adenylate kinase 2
APOC1 apolipoprotein C-I
ARHGAP33 Rho GTPase activating protein 33
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ASIC3 acid sensing (proton gated) ion channel 3
ATF6B activating transcription factor 6 beta
BMP5 bone morphogenetic protein 5
C19ORF73 chromosome 19 open reading frame 73
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CD200 CD200 molecule
CDH8 cadherin 8, type 2
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CEP97 centrosomal protein 97kDa
CERS4 ceramide synthase 4
CNTNAP2 contactin associated protein-like 2
COL4A6 collagen, type IV, alpha 6
COL8A1 collagen, type VIII, alpha 1
COLEC10 collectin sub-family member 10 (C-type lectin)
DBF4B DBF4 zinc finger B
DFNB31 deafness, autosomal recessive 31
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DOCK4 dedicator of cytokinesis 4
DOCK5 dedicator of cytokinesis 5
EFNB3 ephrin-B3
EGFR epidermal growth factor receptor
EHBP1L1 EH domain binding protein 1-like 1
ERCC2 excision repair cross-complementation group 2
EZR ezrin
FBXO9 F-box protein 9
FKBP8 FK506 binding protein 8, 38kDa
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GK2 glycerol kinase 2
GRIK5 glutamate receptor, ionotropic, kainate 5
GSDMD gasdermin D
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HBS1L HBS1-like translational GTPase
HNMT histamine N-methyltransferase
HOMER3 homer scaffolding protein 3
HOXC4 homeobox C4
HSF2 heat shock transcription factor 2
ITSN1 intersectin 1 (SH3 domain protein)
KCNK2 potassium channel, two pore domain subfamily K, member 2
KIAA0319L KIAA0319-like
KRT24 keratin 24, type I
KRT83 keratin 83, type II
LTB lymphotoxin beta (TNF superfamily, member 3)
LTB4R leukotriene B4 receptor
MAP4 microtubule-associated protein 4
MFAP3L microfibrillar-associated protein 3-like
MPPE1 metallophosphoesterase 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTA1 metastasis associated 1
MYH6 myosin, heavy chain 6, cardiac muscle, alpha
MYL10 myosin, light chain 10, regulatory
NPTX2 neuronal pentraxin II
NPY6R neuropeptide Y receptor Y6 (pseudogene)
NRP2 neuropilin 2
PBX2 pre-B-cell leukemia homeobox 2
PCDH1 protocadherin 1
PLK3 polo-like kinase 3
PRPH peripherin
PRSS53 protease, serine, 53
RAD52 RAD52 homolog (S. cerevisiae)
RFPL1S RFPL1 antisense RNA 1
RHBG Rh family, B glycoprotein (gene/pseudogene)
RNF126P1 ring finger protein 126 pseudogene 1
S100A8 S100 calcium binding protein A8
SAFB scaffold attachment factor B
SCAI suppressor of cancer cell invasion
SIRT5 sirtuin 5
SLC12A8 solute carrier family 12, member 8
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SMIM14 small integral membrane protein 14
SPRR1B small proline-rich protein 1B
SPTBN1 spectrin, beta, non-erythrocytic 1
SYNJ2 synaptojanin 2
TM4SF1 transmembrane 4 L six family member 1
TMEM242 transmembrane protein 242
TMPRSS15 transmembrane protease, serine 15
TNS1 tensin 1
TSPAN9 tetraspanin 9
TUBA3C tubulin, alpha 3c
VAC14 Vac14 homolog (S. cerevisiae)
VASH2 vasohibin 2
VIPR1 vasoactive intestinal peptide receptor 1
VWA5A von Willebrand factor A domain containing 5A
WNK1 WNK lysine deficient protein kinase 1
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF287 zinc finger protein 287
ZNF473 zinc finger protein 473
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ARC activity-regulated cytoskeleton-associated protein
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARMC4 armadillo repeat containing 4
ART1 ADP-ribosyltransferase 1
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATHL1 ATH1, acid trehalase-like 1 (yeast)
C1ORF105 chromosome 1 open reading frame 105
C3 complement component 3
CAPN15 calpain 15
CCDC121 coiled-coil domain containing 121
CCDC186 coiled-coil domain containing 186
CCDC69 coiled-coil domain containing 69
CCDC88C coiled-coil domain containing 88C
CD83 CD83 molecule
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CIDEC cell death-inducing DFFA-like effector c
CNGB3 cyclic nucleotide gated channel beta 3
CTSF cathepsin F
DCLRE1A DNA cross-link repair 1A
ENO3 enolase 3 (beta, muscle)
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERN2 endoplasmic reticulum to nucleus signaling 2
F2R coagulation factor II (thrombin) receptor
FAM155B family with sequence similarity 155, member B
FBXO31 F-box protein 31
FMOD fibromodulin
FOSL1 FOS-like antigen 1
FRS2 fibroblast growth factor receptor substrate 2
GMPR guanosine monophosphate reductase
HIRA histone cell cycle regulator
HIST1H2BJ histone cluster 1, H2bj
HOOK1 hook microtubule-tethering protein 1
HOXC10 homeobox C10
HYI hydroxypyruvate isomerase (putative)
IL12RB1 interleukin 12 receptor, beta 1
INO80D INO80 complex subunit D
IRF1 interferon regulatory factor 1
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGA10 integrin, alpha 10
KLF2 Kruppel-like factor 2
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LIN7A lin-7 homolog A (C. elegans)
LINC00115 long intergenic non-protein coding RNA 115
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MICALL2 MICAL-like 2
MNX1 motor neuron and pancreas homeobox 1
MSI1 musashi RNA-binding protein 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MVP major vault protein
NAT6 N-acetyltransferase 6 (GCN5-related)
NCS1 neuronal calcium sensor 1
NEK11 NIMA-related kinase 11
NIPAL2 NIPA-like domain containing 2
NKX3-2 NK3 homeobox 2
NPFFR1 neuropeptide FF receptor 1
NT5C 5', 3'-nucleotidase, cytosolic
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PRR14L proline rich 14-like
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PRSS22 protease, serine, 22
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RAB30 RAB30, member RAS oncogene family
RASAL1 RAS protein activator like 1 (GAP1 like)
RP2 retinitis pigmentosa 2 (X-linked recessive)
SAYSD1 SAYSVFN motif domain containing 1
SFT2D2 SFT2 domain containing 2
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SPINK5 serine peptidase inhibitor, Kazal type 5
SSBP3 single stranded DNA binding protein 3
TCTN2 tectonic family member 2
TESC tescalcin
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
THBS3 thrombospondin 3
TMCC2 transmembrane and coiled-coil domain family 2
TMEM120B transmembrane protein 120B
TMEM121 transmembrane protein 121
TMEM180 transmembrane protein 180
TMEM184C transmembrane protein 184C
TRAIP TRAF interacting protein
TWSG1 twisted gastrulation BMP signaling modulator 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VEGFC vascular endothelial growth factor C
WNT10B wingless-type MMTV integration site family, member 10B
ZNF141 zinc finger protein 141
ZNF211 zinc finger protein 211
ZNF428 zinc finger protein 428
ZNF484 zinc finger protein 484
ZNF76 zinc finger protein 76
ZNF770 zinc finger protein 770
ZNF8 zinc finger protein 8
ZSCAN31 zinc finger and SCAN domain containing 31