| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the hydroxyzine-1941 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| ACLY | ATP citrate lyase |
| ACOT9 | acyl-CoA thioesterase 9 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ANKRD12 | ankyrin repeat domain 12 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
| AZI2 | 5-azacytidine induced 2 |
| BBIP1 | BBSome interacting protein 1 |
| BCL7C | B-cell CLL/lymphoma 7C |
| BCORL1 | BCL6 corepressor-like 1 |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| BMP2K | BMP2 inducible kinase |
| BNIP1 | BCL2/adenovirus E1B 19kDa interacting protein 1 |
| C17ORF62 | chromosome 17 open reading frame 62 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C20ORF27 | chromosome 20 open reading frame 27 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CD302 | CD302 molecule |
| CD58 | CD58 molecule |
| CER1 | cerberus 1, DAN family BMP antagonist |
| CHML | choroideremia-like (Rab escort protein 2) |
| CIZ1 | CDKN1A interacting zinc finger protein 1 |
| CLCC1 | chloride channel CLIC-like 1 |
| COBL | cordon-bleu WH2 repeat protein |
| CPOX | coproporphyrinogen oxidase |
| CPT2 | carnitine palmitoyltransferase 2 |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 |
| CUL4A | cullin 4A |
| E2F5 | E2F transcription factor 5, p130-binding |
| EID1 | EP300 interacting inhibitor of differentiation 1 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| EPS8L1 | EPS8-like 1 |
| EVI5 | ecotropic viral integration site 5 |
| F11R | F11 receptor |
| F2R | coagulation factor II (thrombin) receptor |
| FAM149B1 | family with sequence similarity 149, member B1 |
| FH | fumarate hydratase |
| GLRX | glutaredoxin (thioltransferase) |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GSK3A | glycogen synthase kinase 3 alpha |
| H2AFY | H2A histone family, member Y |
| HAND1 | heart and neural crest derivatives expressed 1 |
| HMGN5 | high mobility group nucleosome binding domain 5 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| INHBC | inhibin, beta C |
| IQCG | IQ motif containing G |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
| KANK1 | KN motif and ankyrin repeat domains 1 |
| KAZALD1 | Kazal-type serine peptidase inhibitor domain 1 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 |
| KLHL23 | kelch-like family member 23 |
| KLHL7 | kelch-like family member 7 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) |
| KRIT1 | KRIT1, ankyrin repeat containing |
| KRT86 | keratin 86, type II |
| LIMK2 | LIM domain kinase 2 |
| LPP | LIM domain containing preferred translocation partner in lipoma |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MCM4 | minichromosome maintenance complex component 4 |
| MED14 | mediator complex subunit 14 |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MTF2 | metal response element binding transcription factor 2 |
| NBR1 | neighbor of BRCA1 gene 1 |
| NT5C2 | 5'-nucleotidase, cytosolic II |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 |
| NUPL2 | nucleoporin like 2 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PGRMC2 | progesterone receptor membrane component 2 |
| PIDD1 | p53-induced death domain protein 1 |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) |
| PKP2 | plakophilin 2 |
| PLCE1 | phospholipase C, epsilon 1 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 |
| RAD1 | RAD1 checkpoint DNA exonuclease |
| RAD17 | RAD17 homolog (S. pombe) |
| RANBP3 | RAN binding protein 3 |
| RIOK3 | RIO kinase 3 |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) |
| RPL7 | ribosomal protein L7 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 |
| SEC23B | Sec23 homolog B (S. cerevisiae) |
| SFTPB | surfactant protein B |
| SLK | STE20-like kinase |
| SNX10 | sorting nexin 10 |
| SOAT1 | sterol O-acyltransferase 1 |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
| TIA1 | TIA1 cytotoxic granule-associated RNA binding protein |
| TMEM194A | transmembrane protein 194A |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TPT1 | tumor protein, translationally-controlled 1 |
| TTC37 | tetratricopeptide repeat domain 37 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| ZNF3 | zinc finger protein 3 |
| ZNF652 | zinc finger protein 652 |
| Symbol | Name |
|---|---|
| ADGRF1 | adhesion G protein-coupled receptor F1 |
| BCKDHA | branched chain keto acid dehydrogenase E1, alpha polypeptide |
| BLMH | bleomycin hydrolase |
| C3ORF18 | chromosome 3 open reading frame 18 |
| CCDC47 | coiled-coil domain containing 47 |
| CCNL1 | cyclin L1 |
| CEP70 | centrosomal protein 70kDa |
| CEP85 | centrosomal protein 85kDa |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CIDEC | cell death-inducing DFFA-like effector c |
| CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) |
| DCP1A | decapping mRNA 1A |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| EPS8L2 | EPS8-like 2 |
| ETV4 | ets variant 4 |
| EVPL | envoplakin |
| FAM131A | family with sequence similarity 131, member A |
| FAM134C | family with sequence similarity 134, member C |
| FAM188A | family with sequence similarity 188, member A |
| FAM193B | family with sequence similarity 193, member B |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| G6PD | glucose-6-phosphate dehydrogenase |
| GATA6 | GATA binding protein 6 |
| GPRC5D | G protein-coupled receptor, class C, group 5, member D |
| GPX2 | glutathione peroxidase 2 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| GSDMD | gasdermin D |
| HIRA | histone cell cycle regulator |
| HIST3H2A | histone cluster 3, H2a |
| HS1BP3 | HCLS1 binding protein 3 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| IL24 | interleukin 24 |
| KIAA0753 | KIAA0753 |
| KIF20B | kinesin family member 20B |
| KLHL26 | kelch-like family member 26 |
| LAMB2 | laminin, beta 2 (laminin S) |
| LMBR1L | limb development membrane protein 1-like |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| METTL1 | methyltransferase like 1 |
| MICALL2 | MICAL-like 2 |
| MITF | microphthalmia-associated transcription factor |
| MPV17 | MpV17 mitochondrial inner membrane protein |
| MRPL12 | mitochondrial ribosomal protein L12 |
| MRPS34 | mitochondrial ribosomal protein S34 |
| MSX1 | msh homeobox 1 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MX1 | MX dynamin-like GTPase 1 |
| MYO19 | myosin XIX |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NUBP1 | nucleotide binding protein 1 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| PADI1 | peptidyl arginine deiminase, type I |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PI4KA | phosphatidylinositol 4-kinase, catalytic, alpha |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) |
| PYCR1 | pyrroline-5-carboxylate reductase 1 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
| RAB36 | RAB36, member RAS oncogene family |
| RABL3 | RAB, member of RAS oncogene family-like 3 |
| RAF1 | Raf-1 proto-oncogene, serine/threonine kinase |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RHOB | ras homolog family member B |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RNF122 | ring finger protein 122 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SALL2 | spalt-like transcription factor 2 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC27A5 | solute carrier family 27 (fatty acid transporter), member 5 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC36A1 | solute carrier family 36 (proton/amino acid symporter), member 1 |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 |
| SOD3 | superoxide dismutase 3, extracellular |
| SPX | spexin hormone |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 |
| TMEM164 | transmembrane protein 164 |
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TOMM22 | translocase of outer mitochondrial membrane 22 homolog (yeast) |
| TPCN1 | two pore segment channel 1 |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| ZIM2 | zinc finger, imprinted 2 |
| ZNF136 | zinc finger protein 136 |
| ZNF358 | zinc finger protein 358 |
| ZNF552 | zinc finger protein 552 |
| ZNF580 | zinc finger protein 580 |
| ZSCAN9 | zinc finger and SCAN domain containing 9 |
