| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the hydroxyzine-2024 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD2 | abhydrolase domain containing 2 |
| ABI2 | abl-interactor 2 |
| ADD1 | adducin 1 (alpha) |
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
| APOC1 | apolipoprotein C-I |
| AQP6 | aquaporin 6, kidney specific |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARL1 | ADP-ribosylation factor-like 1 |
| ARRB2 | arrestin, beta 2 |
| ARSB | arylsulfatase B |
| ASPH | aspartate beta-hydroxylase |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| B3GNTL1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 |
| BPIFA1 | BPI fold containing family A, member 1 |
| CAST | calpastatin |
| CCPG1 | cell cycle progression 1 |
| CDHR2 | cadherin-related family member 2 |
| CEP131 | centrosomal protein 131kDa |
| CHGB | chromogranin B |
| CHN2 | chimerin 2 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CLIC4 | chloride intracellular channel 4 |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CTRL | chymotrypsin-like |
| CUL3 | cullin 3 |
| CUL4B | cullin 4B |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| CYB561 | cytochrome b561 |
| DBP | D site of albumin promoter (albumin D-box) binding protein |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DUSP13 | dual specificity phosphatase 13 |
| ELMO2 | engulfment and cell motility 2 |
| ENOX2 | ecto-NOX disulfide-thiol exchanger 2 |
| FAM189A2 | family with sequence similarity 189, member A2 |
| FAM64A | family with sequence similarity 64, member A |
| FLI1 | Fli-1 proto-oncogene, ETS transcription factor |
| GLRA2 | glycine receptor, alpha 2 |
| GLUL | glutamate-ammonia ligase |
| GPX2 | glutathione peroxidase 2 |
| HBB | hemoglobin, beta |
| HOOK2 | hook microtubule-tethering protein 2 |
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| KAT6B | K(lysine) acetyltransferase 6B |
| KAT8 | K(lysine) acetyltransferase 8 |
| KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 |
| KIR2DL5A | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LTB4R | leukotriene B4 receptor |
| MAGOH2P | mago-nashi homolog 2, pseudogene |
| MAGOHB | mago-nashi homolog B (Drosophila) |
| MAP2K4 | mitogen-activated protein kinase kinase 4 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| METRN | meteorin, glial cell differentiation regulator |
| MOB1A | MOB kinase activator 1A |
| MYT1 | myelin transcription factor 1 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| PAK2 | p21 protein (Cdc42/Rac)-activated kinase 2 |
| PAX1 | paired box 1 |
| PC | pyruvate carboxylase |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor |
| PECAM1 | platelet/endothelial cell adhesion molecule 1 |
| PEX14 | peroxisomal biogenesis factor 14 |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| PKP3 | plakophilin 3 |
| PLD2 | phospholipase D2 |
| POFUT1 | protein O-fucosyltransferase 1 |
| RGS14 | regulator of G-protein signaling 14 |
| RIN3 | Ras and Rab interactor 3 |
| RNASE3 | ribonuclease, RNase A family, 3 |
| SCAMP1 | secretory carrier membrane protein 1 |
| SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 |
| SLMO2 | slowmo homolog 2 (Drosophila) |
| SMA4 | glucuronidase, beta pseudogene |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) |
| STBD1 | starch binding domain 1 |
| TES | testin LIM domain protein |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TPR | translocated promoter region, nuclear basket protein |
| UBQLN4 | ubiquilin 4 |
| USF2 | upstream transcription factor 2, c-fos interacting |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| WDR76 | WD repeat domain 76 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZNF117 | zinc finger protein 117 |
| ZNF224 | zinc finger protein 224 |
| ZNF551 | zinc finger protein 551 |
| ZNF79 | zinc finger protein 79 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ABCF3 | ATP-binding cassette, sub-family F (GCN20), member 3 |
| ABHD3 | abhydrolase domain containing 3 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase |
| ASCC1 | activating signal cointegrator 1 complex subunit 1 |
| ATAD2B | ATPase family, AAA domain containing 2B |
| ATXN2 | ataxin 2 |
| AVEN | apoptosis, caspase activation inhibitor |
| BAG3 | BCL2-associated athanogene 3 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BCCIP | BRCA2 and CDKN1A interacting protein |
| BCL7C | B-cell CLL/lymphoma 7C |
| C10ORF2 | chromosome 10 open reading frame 2 |
| C12ORF29 | chromosome 12 open reading frame 29 |
| CAAP1 | caspase activity and apoptosis inhibitor 1 |
| CCDC6 | coiled-coil domain containing 6 |
| CCDC86 | coiled-coil domain containing 86 |
| CD320 | CD320 molecule |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CPOX | coproporphyrinogen oxidase |
| CRYL1 | crystallin, lambda 1 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CXORF40A | chromosome X open reading frame 40A |
| CYCS | cytochrome c, somatic |
| CYTH2 | cytohesin 2 |
| DCAF6 | DDB1 and CUL4 associated factor 6 |
| DCUN1D2 | DCN1, defective in cullin neddylation 1, domain containing 2 |
| DDX39A | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A |
| DEAF1 | DEAF1 transcription factor |
| DUSP12 | dual specificity phosphatase 12 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FAM136A | family with sequence similarity 136, member A |
| FAM206A | family with sequence similarity 206, member A |
| FANCF | Fanconi anemia, complementation group F |
| FANCL | Fanconi anemia, complementation group L |
| FBXL4 | F-box and leucine-rich repeat protein 4 |
| FTO | fat mass and obesity associated |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GPATCH2 | G patch domain containing 2 |
| GPN2 | GPN-loop GTPase 2 |
| GRINA | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) |
| GSR | glutathione reductase |
| GTPBP6 | GTP binding protein 6 (putative) |
| HMGB3P1 | high mobility group box 3 pseudogene 1 |
| KIFC1 | kinesin family member C1 |
| LIMA1 | LIM domain and actin binding 1 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MCM10 | minichromosome maintenance complex component 10 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MRPL19 | mitochondrial ribosomal protein L19 |
| MRPL33 | mitochondrial ribosomal protein L33 |
| MTERF3 | mitochondrial transcription termination factor 3 |
| MTHFD1 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase |
| NDEL1 | nudE neurodevelopment protein 1-like 1 |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| NEK11 | NIMA-related kinase 11 |
| NFU1 | NFU1 iron-sulfur cluster scaffold |
| NRBP1 | nuclear receptor binding protein 1 |
| NRIP3 | nuclear receptor interacting protein 3 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PABPC3 | poly(A) binding protein, cytoplasmic 3 |
| PCNA | proliferating cell nuclear antigen |
| PEMT | phosphatidylethanolamine N-methyltransferase |
| PEPD | peptidase D |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
| POLI | polymerase (DNA directed) iota |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PWP2 | PWP2 periodic tryptophan protein homolog (yeast) |
| RAP1A | RAP1A, member of RAS oncogene family |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RPS14P3 | ribosomal protein S14 pseudogene 3 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 |
| SMAD7 | SMAD family member 7 |
| SMCO4 | single-pass membrane protein with coiled-coil domains 4 |
| SMNDC1 | survival motor neuron domain containing 1 |
| SP3 | Sp3 transcription factor |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TCTN2 | tectonic family member 2 |
| TK1 | thymidine kinase 1, soluble |
| TMPRSS6 | transmembrane protease, serine 6 |
| TRAPPC11 | trafficking protein particle complex 11 |
| TRIM26 | tripartite motif containing 26 |
| TRIM8 | tripartite motif containing 8 |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| UNKL | unkempt family zinc finger-like |
| UROS | uroporphyrinogen III synthase |
| USB1 | U6 snRNA biogenesis 1 |
| WDR3 | WD repeat domain 3 |
| WDR82 | WD repeat domain 82 |
| WT1-AS | WT1 antisense RNA |
| XBP1 | X-box binding protein 1 |
| ZCCHC8 | zinc finger, CCHC domain containing 8 |
| ZFAND3 | zinc finger, AN1-type domain 3 |
| ZNF14 | zinc finger protein 14 |
| ZNF32 | zinc finger protein 32 |
| ZNF652 | zinc finger protein 652 |
