| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the hydroxyzine-5006 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ABHD17B | abhydrolase domain containing 17B |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ACPP | acid phosphatase, prostate |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CARD14 | caspase recruitment domain family, member 14 |
| CDC14B | cell division cycle 14B |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CFAP69 | cilia and flagella associated protein 69 |
| CIC | capicua transcriptional repressor |
| CLTA | clathrin, light chain A |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) |
| CPB1 | carboxypeptidase B1 (tissue) |
| CREBZF | CREB/ATF bZIP transcription factor |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like |
| CTSF | cathepsin F |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CYLC1 | cylicin, basic protein of sperm head cytoskeleton 1 |
| DEFB4A | defensin, beta 4A |
| DMPK | dystrophia myotonica-protein kinase |
| DPF1 | D4, zinc and double PHD fingers family 1 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa |
| EPHB2 | EPH receptor B2 |
| ERCC2 | excision repair cross-complementation group 2 |
| FAM212B | family with sequence similarity 212, member B |
| FCGBP | Fc fragment of IgG binding protein |
| FSCN1 | fascin actin-bundling protein 1 |
| FUS | FUS RNA binding protein |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GJA4 | gap junction protein, alpha 4, 37kDa |
| GPR3 | G protein-coupled receptor 3 |
| GPRC5D | G protein-coupled receptor, class C, group 5, member D |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HIPK2 | homeodomain interacting protein kinase 2 |
| HNF1A | HNF1 homeobox A |
| HOMER3 | homer scaffolding protein 3 |
| HYMAI | hydatidiform mole associated and imprinted (non-protein coding) |
| IL1B | interleukin 1, beta |
| INHBA | inhibin, beta A |
| INHBE | inhibin, beta E |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| KANSL3 | KAT8 regulatory NSL complex subunit 3 |
| KIDINS220 | kinase D-interacting substrate, 220kDa |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 |
| LENEP | lens epithelial protein |
| LIF | leukemia inhibitory factor |
| LOC100127972 | uncharacterized LOC100127972 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MAGOH2P | mago-nashi homolog 2, pseudogene |
| MAPK8 | mitogen-activated protein kinase 8 |
| MCTP1 | multiple C2 domains, transmembrane 1 |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MTCP1 | mature T-cell proliferation 1 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NDST1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NIPAL2 | NIPA-like domain containing 2 |
| PAX8 | paired box 8 |
| PHTF2 | putative homeodomain transcription factor 2 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLLP | plasmolipin |
| POU5F1B | POU class 5 homeobox 1B |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| PURG | purine-rich element binding protein G |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| RGS14 | regulator of G-protein signaling 14 |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RNF39 | ring finger protein 39 |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SIDT2 | SID1 transmembrane family, member 2 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SLC1A7 | solute carrier family 1 (glutamate transporter), member 7 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SP1 | Sp1 transcription factor |
| STAB2 | stabilin 2 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TBL2 | transducin (beta)-like 2 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TOP3B | topoisomerase (DNA) III beta |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| TTLL3 | tubulin tyrosine ligase-like family member 3 |
| TUBA3C | tubulin, alpha 3c |
| WAPAL | wings apart-like homolog (Drosophila) |
| WSCD1 | WSC domain containing 1 |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| Symbol | Name |
|---|---|
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ADAP1 | ArfGAP with dual PH domains 1 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| CARD8 | caspase recruitment domain family, member 8 |
| CCDC68 | coiled-coil domain containing 68 |
| CCDC85C | coiled-coil domain containing 85C |
| CD302 | CD302 molecule |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| CPTP | ceramide-1-phosphate transfer protein |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| DNAL4 | dynein, axonemal, light chain 4 |
| EFNA3 | ephrin-A3 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| ELMO3 | engulfment and cell motility 3 |
| ERCC4 | excision repair cross-complementation group 4 |
| FAM155A | family with sequence similarity 155, member A |
| FAM188A | family with sequence similarity 188, member A |
| FANCE | Fanconi anemia, complementation group E |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
| GLB1L2 | galactosidase, beta 1-like 2 |
| GLI3 | GLI family zinc finger 3 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFT54 | intraflagellar transport 54 |
| INO80D | INO80 complex subunit D |
| ISG15 | ISG15 ubiquitin-like modifier |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA0556 | KIAA0556 |
| KLC2 | kinesin light chain 2 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| L2HGDH | L-2-hydroxyglutarate dehydrogenase |
| LAMB3 | laminin, beta 3 |
| LHX6 | LIM homeobox 6 |
| LRRC16A | leucine rich repeat containing 16A |
| LRRC61 | leucine rich repeat containing 61 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| METTL2B | methyltransferase like 2B |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| NABP2 | nucleic acid binding protein 2 |
| NDE1 | nudE neurodevelopment protein 1 |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| NECAP2 | NECAP endocytosis associated 2 |
| NME5 | NME/NM23 family member 5 |
| NPY1R | neuropeptide Y receptor Y1 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PER3 | period circadian clock 3 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PTGES | prostaglandin E synthase |
| RAD54L | RAD54-like (S. cerevisiae) |
| RFTN1 | raftlin, lipid raft linker 1 |
| RNF122 | ring finger protein 122 |
| RPGRIP1L | RPGRIP1-like |
| S100A9 | S100 calcium binding protein A9 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SH2D4A | SH2 domain containing 4A |
| SIX1 | SIX homeobox 1 |
| SLC10A3 | solute carrier family 10, member 3 |
| SNIP1 | Smad nuclear interacting protein 1 |
| SRPX | sushi-repeat containing protein, X-linked |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TMEM180 | transmembrane protein 180 |
| TP53BP1 | tumor protein p53 binding protein 1 |
| TRAPPC2 | trafficking protein particle complex 2 |
| TRIM21 | tripartite motif containing 21 |
| TTBK2 | tau tubulin kinase 2 |
| UBE2O | ubiquitin-conjugating enzyme E2O |
| ULBP2 | UL16 binding protein 2 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| VGF | VGF nerve growth factor inducible |
| WDR25 | WD repeat domain 25 |
| ZNF211 | zinc finger protein 211 |
| ZNF219 | zinc finger protein 219 |
| ZNF35 | zinc finger protein 35 |
| ZNF350 | zinc finger protein 350 |
| ZNF639 | zinc finger protein 639 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
