| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the hydroxyzine-6660 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCG4 | ATP-binding cassette, sub-family G (WHITE), member 4 |
| ACAN | aggrecan |
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| APOB | apolipoprotein B |
| ASPN | asporin |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 |
| AURKC | aurora kinase C |
| BCL2 | B-cell CLL/lymphoma 2 |
| BMP7 | bone morphogenetic protein 7 |
| C11ORF21 | chromosome 11 open reading frame 21 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CALCR | calcitonin receptor |
| CALD1 | caldesmon 1 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCL24 | chemokine (C-C motif) ligand 24 |
| CDKL1 | cyclin-dependent kinase-like 1 (CDC2-related kinase) |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| COL1A2 | collagen, type I, alpha 2 |
| CSDC2 | cold shock domain containing C2, RNA binding |
| DACH1 | dachshund family transcription factor 1 |
| DBF4B | DBF4 zinc finger B |
| DEFA4 | defensin, alpha 4, corticostatin |
| DIAPH2-AS1 | DIAPH2 antisense RNA 1 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DZIP1 | DAZ interacting zinc finger protein 1 |
| EPS8L1 | EPS8-like 1 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ETV1 | ets variant 1 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FLI1 | Fli-1 proto-oncogene, ETS transcription factor |
| GAB1 | GRB2-associated binding protein 1 |
| GABRG3 | gamma-aminobutyric acid (GABA) A receptor, gamma 3 |
| GAD2 | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) |
| GATA3 | GATA binding protein 3 |
| GPLD1 | glycosylphosphatidylinositol specific phospholipase D1 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| HCN2 | hyperpolarization activated cyclic nucleotide gated potassium channel 2 |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 |
| HIST1H2BM | histone cluster 1, H2bm |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| IGL | immunoglobulin lambda locus |
| ITM2A | integral membrane protein 2A |
| JAM2 | junctional adhesion molecule 2 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| LAT2 | linker for activation of T cells family, member 2 |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| LY6H | lymphocyte antigen 6 complex, locus H |
| MAPK10 | mitogen-activated protein kinase 10 |
| MED18 | mediator complex subunit 18 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MR1 | major histocompatibility complex, class I-related |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| NCAM1 | neural cell adhesion molecule 1 |
| NDNF | neuron-derived neurotrophic factor |
| NUP214 | nucleoporin 214kDa |
| OLFM1 | olfactomedin 1 |
| OMD | osteomodulin |
| ONECUT2 | one cut homeobox 2 |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| PCDHB3 | protocadherin beta 3 |
| PCDHGB6 | protocadherin gamma subfamily B, 6 |
| PDGFB | platelet-derived growth factor beta polypeptide |
| POU6F1 | POU class 6 homeobox 1 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PRDM10 | PR domain containing 10 |
| PRKG1 | protein kinase, cGMP-dependent, type I |
| PTPRF | protein tyrosine phosphatase, receptor type, F |
| PVR | poliovirus receptor |
| RABGAP1 | RAB GTPase activating protein 1 |
| RALGPS1 | Ral GEF with PH domain and SH3 binding motif 1 |
| RDH5 | retinol dehydrogenase 5 (11-cis/9-cis) |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase |
| RORA | RAR-related orphan receptor A |
| RPL13 | ribosomal protein L13 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SCN11A | sodium channel, voltage gated, type XI alpha subunit |
| SCNN1B | sodium channel, non voltage gated 1 beta subunit |
| SLA | Src-like-adaptor |
| SLC25A30 | solute carrier family 25, member 30 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SPRYD7 | SPRY domain containing 7 |
| TBR1 | T-box, brain, 1 |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TEP1 | telomerase-associated protein 1 |
| TFEC | transcription factor EC |
| TLN2 | talin 2 |
| TLX2 | T-cell leukemia homeobox 2 |
| TNIK | TRAF2 and NCK interacting kinase |
| TP53 | tumor protein p53 |
| TPM2 | tropomyosin 2 (beta) |
| WNK1 | WNK lysine deficient protein kinase 1 |
| ZNF225 | zinc finger protein 225 |
| ZNF287 | zinc finger protein 287 |
| ZNRF4 | zinc and ring finger 4 |
| ZXDB | zinc finger, X-linked, duplicated B |
| Symbol | Name |
|---|---|
| AMT | aminomethyltransferase |
| ANKRD36 | ankyrin repeat domain 36 |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ARSB | arylsulfatase B |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BBC3 | BCL2 binding component 3 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| C5ORF42 | chromosome 5 open reading frame 42 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CAPN15 | calpain 15 |
| CASP5 | caspase 5, apoptosis-related cysteine peptidase |
| CD101 | CD101 molecule |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
| CD82 | CD82 molecule |
| CDON | cell adhesion associated, oncogene regulated |
| CELSR3 | cadherin, EGF LAG seven-pass G-type receptor 3 |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CPNE7 | copine VII |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FGF23 | fibroblast growth factor 23 |
| FLJ21369 | uncharacterized protein FLJ21369 |
| FOXN2 | forkhead box N2 |
| GALT | galactose-1-phosphate uridylyltransferase |
| GAS8 | growth arrest-specific 8 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H2AK | histone cluster 1, H2ak |
| HIST1H2BN | histone cluster 1, H2bn |
| HIST1H3F | histone cluster 1, H3f |
| HIST1H4E | histone cluster 1, H4e |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HOXC10 | homeobox C10 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IFNA14 | interferon, alpha 14 |
| IFT54 | intraflagellar transport 54 |
| IL36RN | interleukin 36 receptor antagonist |
| JMJD4 | jumonji domain containing 4 |
| KCNK15 | potassium channel, two pore domain subfamily K, member 15 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| LIPG | lipase, endothelial |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MMP3 | matrix metallopeptidase 3 |
| MMRN2 | multimerin 2 |
| MTSS1L | metastasis suppressor 1-like |
| MYL5 | myosin, light chain 5, regulatory |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| OSBP2 | oxysterol binding protein 2 |
| PDE8B | phosphodiesterase 8B |
| PLA1A | phospholipase A1 member A |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRSS53 | protease, serine, 53 |
| PTPRH | protein tyrosine phosphatase, receptor type, H |
| RAB3A | RAB3A, member RAS oncogene family |
| RAB40A | RAB40A, member RAS oncogene family |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RAI2 | retinoic acid induced 2 |
| RNF2 | ring finger protein 2 |
| RPH3A | rabphilin 3A |
| SCIN | scinderin |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SP1 | Sp1 transcription factor |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| THBS3 | thrombospondin 3 |
| TIGD6 | tigger transposable element derived 6 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TMEM180 | transmembrane protein 180 |
| TMSB15A | thymosin beta 15a |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| TNFSF12 | tumor necrosis factor (ligand) superfamily, member 12 |
| TTLL7 | tubulin tyrosine ligase-like family member 7 |
| VGF | VGF nerve growth factor inducible |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| ZNF205 | zinc finger protein 205 |
| ZNF215 | zinc finger protein 215 |
| ZNF254 | zinc finger protein 254 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF528 | zinc finger protein 528 |
