hydroxyzine Gene Set

Dataset	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category	transcriptomics
Type	small molecule perturbation
Description	A N-alkylpiperazine that is piperzine in which the nitrogens atoms are substituted by 2-(2-hydroxyethoxy)ethyl and (4-chlorophenyl)(phenyl)methyl groups respectively. (Chemical Entities of Biological Interest Ontology, CHEBI_5818)
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Genes

6 genes differentially expressed following the hydroxyzine small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol	Name	Standardized Value
SNAP25	synaptosomal-associated protein, 25kDa	4.06444
NOS3	nitric oxide synthase 3 (endothelial cell)	3.76621
STUB1	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase	3.67169
FADS3	fatty acid desaturase 3	3.44277
BLTP2	bridge-like lipid transfer protein family member 2	3.24071

decreased expression

Symbol	Name	Standardized Value
YME1L1	YME1-like 1 ATPase	-3.14992