| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the hyoscyamine-1424 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM10 | ADAM metallopeptidase domain 10 |
| AIMP2 | aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 |
| ALDOB | aldolase B, fructose-bisphosphate |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ANKRD12 | ankyrin repeat domain 12 |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
| ARIH2 | ariadne RBR E3 ubiquitin protein ligase 2 |
| ASF1A | anti-silencing function 1A histone chaperone |
| ATAD2B | ATPase family, AAA domain containing 2B |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 |
| AURKA | aurora kinase A |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BAIAP2 | BAI1-associated protein 2 |
| BBIP1 | BBSome interacting protein 1 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C2ORF44 | chromosome 2 open reading frame 44 |
| CA14 | carbonic anhydrase XIV |
| CADM3 | cell adhesion molecule 3 |
| CAND1 | cullin-associated and neddylation-dissociated 1 |
| CARTPT | CART prepropeptide |
| CCDC64 | coiled-coil domain containing 64 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| COX11 | COX11 cytochrome c oxidase copper chaperone |
| COX5B | cytochrome c oxidase subunit Vb |
| CRYBG3 | beta-gamma crystallin domain containing 3 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 |
| CYB561 | cytochrome b561 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
| DHX29 | DEAH (Asp-Glu-Ala-His) box polypeptide 29 |
| DUSP1 | dual specificity phosphatase 1 |
| EDAR | ectodysplasin A receptor |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) |
| EEF1E1 | eukaryotic translation elongation factor 1 epsilon 1 |
| EFHC2 | EF-hand domain (C-terminal) containing 2 |
| EIF5B | eukaryotic translation initiation factor 5B |
| EPHB3 | EPH receptor B3 |
| ERCC4 | excision repair cross-complementation group 4 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 |
| FAM76A | family with sequence similarity 76, member A |
| FOXC1 | forkhead box C1 |
| GRSF1 | G-rich RNA sequence binding factor 1 |
| GYPB | glycophorin B (MNS blood group) |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| HSPA13 | heat shock protein 70kDa family, member 13 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IER3IP1 | immediate early response 3 interacting protein 1 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) |
| KCNQ1 | potassium channel, voltage gated KQT-like subfamily Q, member 1 |
| KRT18 | keratin 18, type I |
| LPAR1 | lysophosphatidic acid receptor 1 |
| MLH3 | mutL homolog 3 |
| MMP25 | matrix metallopeptidase 25 |
| MPPED1 | metallophosphoesterase domain containing 1 |
| MRPS12 | mitochondrial ribosomal protein S12 |
| MTMR3 | myotubularin related protein 3 |
| NDRG2 | NDRG family member 2 |
| NOTCH1 | notch 1 |
| OCRL | oculocerebrorenal syndrome of Lowe |
| OPHN1 | oligophrenin 1 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) |
| PARD6A | par-6 family cell polarity regulator alpha |
| PDCD2 | programmed cell death 2 |
| PGK1 | phosphoglycerate kinase 1 |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PNO1 | partner of NOB1 homolog (S. cerevisiae) |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit |
| PRPH2 | peripherin 2 (retinal degeneration, slow) |
| PRRC2C | proline-rich coiled-coil 2C |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAB2A | RAB2A, member RAS oncogene family |
| RANBP1 | RAN binding protein 1 |
| RBM8A | RNA binding motif protein 8A |
| RHOH | ras homolog family member H |
| RPAIN | RPA interacting protein |
| RPL14 | ribosomal protein L14 |
| RPL27A | ribosomal protein L27a |
| RPL37A | ribosomal protein L37a |
| RPL38 | ribosomal protein L38 |
| RPLP2 | ribosomal protein, large, P2 |
| RPS11 | ribosomal protein S11 |
| S100A13 | S100 calcium binding protein A13 |
| SCARB2 | scavenger receptor class B, member 2 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 |
| TAGLN3 | transgelin 3 |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
| TCL1A | T-cell leukemia/lymphoma 1A |
| TMPRSS6 | transmembrane protease, serine 6 |
| TRAM1 | translocation associated membrane protein 1 |
| TXN | thioredoxin |
| UTP18 | UTP18 small subunit (SSU) processome component homolog (yeast) |
| VDAC3 | voltage-dependent anion channel 3 |
| ZNF337 | zinc finger protein 337 |
| ZNF74 | zinc finger protein 74 |
| ZNF770 | zinc finger protein 770 |
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| ACD | adrenocortical dysplasia homolog (mouse) |
| ACP2 | acid phosphatase 2, lysosomal |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| ANAPC2 | anaphase promoting complex subunit 2 |
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit |
| APEH | acylaminoacyl-peptide hydrolase |
| APEX2 | APEX nuclease (apurinic/apyrimidinic endonuclease) 2 |
| ARAF | A-Raf proto-oncogene, serine/threonine kinase |
| ASB6 | ankyrin repeat and SOCS box containing 6 |
| ASL | argininosuccinate lyase |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| AZU1 | azurocidin 1 |
| BANP | BTG3 associated nuclear protein |
| BCL7C | B-cell CLL/lymphoma 7C |
| BRD9 | bromodomain containing 9 |
| BYSL | bystin-like |
| C11ORF68 | chromosome 11 open reading frame 68 |
| C1D | C1D nuclear receptor corepressor |
| C1ORF216 | chromosome 1 open reading frame 216 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CDK8 | cyclin-dependent kinase 8 |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CFL1 | cofilin 1 (non-muscle) |
| CLDN15 | claudin 15 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CLPB | ClpB homolog, mitochondrial AAA ATPase chaperonin |
| CYC1 | cytochrome c-1 |
| DIXDC1 | DIX domain containing 1 |
| DNM1 | dynamin 1 |
| DPP3 | dipeptidyl-peptidase 3 |
| E2F8 | E2F transcription factor 8 |
| EDC4 | enhancer of mRNA decapping 4 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 |
| ELANE | elastase, neutrophil expressed |
| ERI3 | ERI1 exoribonuclease family member 3 |
| EXOC3 | exocyst complex component 3 |
| FAM189B | family with sequence similarity 189, member B |
| FES | FES proto-oncogene, tyrosine kinase |
| GMIP | GEM interacting protein |
| GPS2 | G protein pathway suppressor 2 |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa |
| H1FX | H1 histone family, member X |
| HPCAL1 | hippocalcin-like 1 |
| HSPBP1 | HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 |
| IFITM3 | interferon induced transmembrane protein 3 |
| KLHL21 | kelch-like family member 21 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MACROD1 | MACRO domain containing 1 |
| MFSD10 | major facilitator superfamily domain containing 10 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 |
| MLF2 | myeloid leukemia factor 2 |
| MLST8 | MTOR associated protein, LST8 homolog (S. cerevisiae) |
| MPG | N-methylpurine-DNA glycosylase |
| MRPL12 | mitochondrial ribosomal protein L12 |
| NAGPA | N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase |
| NELFB | negative elongation factor complex member B |
| NELFE | negative elongation factor complex member E |
| NINJ1 | ninjurin 1 |
| PFN1 | profilin 1 |
| PGS1 | phosphatidylglycerophosphate synthase 1 |
| PLK1 | polo-like kinase 1 |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PPA1 | pyrophosphatase (inorganic) 1 |
| PPP1R14B | protein phosphatase 1, regulatory (inhibitor) subunit 14B |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) |
| PRTN3 | proteinase 3 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 |
| RAB4B | RAB4B, member RAS oncogene family |
| RHOG | ras homolog family member G |
| RPL36 | ribosomal protein L36 |
| RPS6KB2 | ribosomal protein S6 kinase, 70kDa, polypeptide 2 |
| RRP1 | ribosomal RNA processing 1 |
| SAC3D1 | SAC3 domain containing 1 |
| SEC61B | Sec61 beta subunit |
| SF3B4 | splicing factor 3b, subunit 4, 49kDa |
| SH3GL1 | SH3-domain GRB2-like 1 |
| SIGMAR1 | sigma non-opioid intracellular receptor 1 |
| SLC38A10 | solute carrier family 38, member 10 |
| SNAP29 | synaptosomal-associated protein, 29kDa |
| SNX6 | sorting nexin 6 |
| SSNA1 | Sjogren syndrome nuclear autoantigen 1 |
| TAF12 | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa |
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 |
| TECR | trans-2,3-enoyl-CoA reductase |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| THAP4 | THAP domain containing 4 |
| THOC6 | THO complex 6 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) |
| TMEM39B | transmembrane protein 39B |
| TRIM28 | tripartite motif containing 28 |
| TTC31 | tetratricopeptide repeat domain 31 |
| TYK2 | tyrosine kinase 2 |
| UBE2M | ubiquitin-conjugating enzyme E2M |
| USP20 | ubiquitin specific peptidase 20 |
| YIF1A | Yip1 interacting factor homolog A (S. cerevisiae) |
| YIPF3 | Yip1 domain family, member 3 |
| ZEB2 | zinc finger E-box binding homeobox 2 |
