| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the hyoscyamine-2271 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACBD4 | acyl-CoA binding domain containing 4 |
| ACTN2 | actinin, alpha 2 |
| ADAMTS7 | ADAM metallopeptidase with thrombospondin type 1 motif, 7 |
| AHSG | alpha-2-HS-glycoprotein |
| AP2A2 | adaptor-related protein complex 2, alpha 2 subunit |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 |
| ASIC4 | acid sensing (proton gated) ion channel family member 4 |
| ATF5 | activating transcription factor 5 |
| ATP10A | ATPase, class V, type 10A |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CCDC64 | coiled-coil domain containing 64 |
| CDON | cell adhesion associated, oncogene regulated |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 |
| CRMP1 | collapsin response mediator protein 1 |
| CRYAA | crystallin, alpha A |
| CSF1 | colony stimulating factor 1 (macrophage) |
| DCN | decorin |
| DDN | dendrin |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
| DOK4 | docking protein 4 |
| ELN | elastin |
| FABP3 | fatty acid binding protein 3, muscle and heart |
| FGF3 | fibroblast growth factor 3 |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GAS2 | growth arrest-specific 2 |
| GAS7 | growth arrest-specific 7 |
| GP5 | glycoprotein V (platelet) |
| GPR182 | G protein-coupled receptor 182 |
| GRM7 | glutamate receptor, metabotropic 7 |
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
| HRG | histidine-rich glycoprotein |
| IFT54 | intraflagellar transport 54 |
| IL1RN | interleukin 1 receptor antagonist |
| IL22 | interleukin 22 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KLF8 | Kruppel-like factor 8 |
| KLHL20 | kelch-like family member 20 |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| LAMC2 | laminin, gamma 2 |
| LRP12 | low density lipoprotein receptor-related protein 12 |
| LSP1 | lymphocyte-specific protein 1 |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| MAGEA3 | melanoma antigen family A3 |
| MAOB | monoamine oxidase B |
| MARK2 | MAP/microtubule affinity-regulating kinase 2 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MED18 | mediator complex subunit 18 |
| MID1 | midline 1 |
| MMP25 | matrix metallopeptidase 25 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NDOR1 | NADPH dependent diflavin oxidoreductase 1 |
| NDUFA2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa |
| NPR1 | natriuretic peptide receptor 1 |
| NTF3 | neurotrophin 3 |
| ONECUT2 | one cut homeobox 2 |
| OPCML | opioid binding protein/cell adhesion molecule-like |
| OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
| PCDH9 | protocadherin 9 |
| PDLIM4 | PDZ and LIM domain 4 |
| PGR | progesterone receptor |
| PNPLA3 | patatin-like phospholipase domain containing 3 |
| PROZ | protein Z, vitamin K-dependent plasma glycoprotein |
| PSMB1 | proteasome (prosome, macropain) subunit, beta type, 1 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 |
| RIN3 | Ras and Rab interactor 3 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RUNX1 | runt-related transcription factor 1 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) |
| SCARA3 | scavenger receptor class A, member 3 |
| SDC2 | syndecan 2 |
| SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SKAP1 | src kinase associated phosphoprotein 1 |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 |
| SLC52A1 | solute carrier family 52 (riboflavin transporter), member 1 |
| SLC6A9 | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| SRGN | serglycin |
| TBX2 | T-box 2 |
| TCEAL2 | transcription elongation factor A (SII)-like 2 |
| THEMIS2 | thymocyte selection associated family member 2 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TNN | tenascin N |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TRBC1 | T cell receptor beta constant 1 |
| TRIM10 | tripartite motif containing 10 |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) |
| ZNF384 | zinc finger protein 384 |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| ALPK1 | alpha-kinase 1 |
| ANKRD36 | ankyrin repeat domain 36 |
| ARRB1 | arrestin, beta 1 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| B9D2 | B9 protein domain 2 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CA11 | carbonic anhydrase XI |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CBR4 | carbonyl reductase 4 |
| CCNT1 | cyclin T1 |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CD34 | CD34 molecule |
| CDK18 | cyclin-dependent kinase 18 |
| CNTN1 | contactin 1 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CORO7 | coronin 7 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DNAL4 | dynein, axonemal, light chain 4 |
| ERCC6 | excision repair cross-complementation group 6 |
| FCHSD2 | FCH and double SH3 domains 2 |
| FLJ11710 | uncharacterized protein FLJ11710 |
| FRK | fyn-related Src family tyrosine kinase |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GRINA | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) |
| GRPR | gastrin-releasing peptide receptor |
| HIST1H2AL | histone cluster 1, H2al |
| HIST1H2AM | histone cluster 1, H2am |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IGSF1 | immunoglobulin superfamily, member 1 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IRF1 | interferon regulatory factor 1 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KDM4C | lysine (K)-specific demethylase 4C |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIAA0232 | KIAA0232 |
| KIAA0319L | KIAA0319-like |
| KLHL21 | kelch-like family member 21 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| NDE1 | nudE neurodevelopment protein 1 |
| NMU | neuromedin U |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PIBF1 | progesterone immunomodulatory binding factor 1 |
| PIGH | phosphatidylinositol glycan anchor biosynthesis, class H |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PLAC1 | placenta-specific 1 |
| PLCD1 | phospholipase C, delta 1 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PROS1 | protein S (alpha) |
| RAB30 | RAB30, member RAS oncogene family |
| RGS19 | regulator of G-protein signaling 19 |
| RNF43 | ring finger protein 43 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) |
| SECISBP2L | SECIS binding protein 2-like |
| SECTM1 | secreted and transmembrane 1 |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SIK1 | salt-inducible kinase 1 |
| SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 |
| SLC16A2 | solute carrier family 16, member 2 (thyroid hormone transporter) |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 |
| SOWAHC | sosondowah ankyrin repeat domain family member C |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| THBS3 | thrombospondin 3 |
| TMEM2 | transmembrane protein 2 |
| TMEM242 | transmembrane protein 242 |
| TNS2 | tensin 2 |
| TRIM5 | tripartite motif containing 5 |
| TSC22D4 | TSC22 domain family, member 4 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| USP20 | ubiquitin specific peptidase 20 |
| YY2 | YY2 transcription factor |
| ZNF10 | zinc finger protein 10 |
| ZNF205 | zinc finger protein 205 |
| ZNF236 | zinc finger protein 236 |
| ZNF365 | zinc finger protein 365 |
| ZNF696 | zinc finger protein 696 |
| ZNF747 | zinc finger protein 747 |
| ZNF862 | zinc finger protein 862 |
