| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the hyoscyamine-5099 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ANXA2P1 | annexin A2 pseudogene 1 |
| APC | adenomatous polyposis coli |
| APOE | apolipoprotein E |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 |
| B3GAT1 | beta-1,3-glucuronyltransferase 1 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 |
| BMP1 | bone morphogenetic protein 1 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| CACNA1S | calcium channel, voltage-dependent, L type, alpha 1S subunit |
| CD82 | CD82 molecule |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| CLSTN3 | calsyntenin 3 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNN1 | calponin 1, basic, smooth muscle |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) |
| COL8A1 | collagen, type VIII, alpha 1 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CSPG4 | chondroitin sulfate proteoglycan 4 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 |
| CUL3 | cullin 3 |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DOCK6 | dedicator of cytokinesis 6 |
| DTNB | dystrobrevin, beta |
| ELK4 | ELK4, ETS-domain protein (SRF accessory protein 1) |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM163A | family with sequence similarity 163, member A |
| FOXN3 | forkhead box N3 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
| GGT1 | gamma-glutamyltransferase 1 |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GLYAT | glycine-N-acyltransferase |
| GREM1 | gremlin 1, DAN family BMP antagonist |
| GRIK2 | glutamate receptor, ionotropic, kainate 2 |
| GUCY1A2 | guanylate cyclase 1, soluble, alpha 2 |
| HIC2 | hypermethylated in cancer 2 |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HOMER3 | homer scaffolding protein 3 |
| HOXB5 | homeobox B5 |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| JAG1 | jagged 1 |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| KLHL22 | kelch-like family member 22 |
| LAT2 | linker for activation of T cells family, member 2 |
| LDAH | lipid droplet associated hydrolase |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| LIPG | lipase, endothelial |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LOX | lysyl oxidase |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MTUS1 | microtubule associated tumor suppressor 1 |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NCR1 | natural cytotoxicity triggering receptor 1 |
| NDUFA5 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 |
| NF1 | neurofibromin 1 |
| NGF | nerve growth factor (beta polypeptide) |
| NPR1 | natriuretic peptide receptor 1 |
| PDIA2 | protein disulfide isomerase family A, member 2 |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PLXND1 | plexin D1 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PQBP1 | polyglutamine binding protein 1 |
| PRAMEF11 | PRAME family member 11 |
| PRKX | protein kinase, X-linked |
| PROSER1 | proline and serine rich 1 |
| QPCT | glutaminyl-peptide cyclotransferase |
| RABGAP1 | RAB GTPase activating protein 1 |
| RARG | retinoic acid receptor, gamma |
| RB1 | retinoblastoma 1 |
| RGS12 | regulator of G-protein signaling 12 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| RREB1 | ras responsive element binding protein 1 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| S100A11 | S100 calcium binding protein A11 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SERPINB13 | serpin peptidase inhibitor, clade B (ovalbumin), member 13 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SOX21 | SRY (sex determining region Y)-box 21 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| SPTBN5 | spectrin, beta, non-erythrocytic 5 |
| STON1 | stonin 1 |
| TBC1D30 | TBC1 domain family, member 30 |
| TFEB | transcription factor EB |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| ZIM2 | zinc finger, imprinted 2 |
| ZNF268 | zinc finger protein 268 |
| ZNF334 | zinc finger protein 334 |
| Symbol | Name |
|---|---|
| ABCB8 | ATP-binding cassette, sub-family B (MDR/TAP), member 8 |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ALPK1 | alpha-kinase 1 |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ASCC1 | activating signal cointegrator 1 complex subunit 1 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| B9D2 | B9 protein domain 2 |
| C14ORF105 | chromosome 14 open reading frame 105 |
| CCDC69 | coiled-coil domain containing 69 |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CDIP1 | cell death-inducing p53 target 1 |
| CDK6 | cyclin-dependent kinase 6 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CENPO | centromere protein O |
| CHMP6 | charged multivesicular body protein 6 |
| CIR1 | corepressor interacting with RBPJ, 1 |
| COG7 | component of oligomeric golgi complex 7 |
| CTSF | cathepsin F |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| EDAR | ectodysplasin A receptor |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FAM184A | family with sequence similarity 184, member A |
| FBRS | fibrosin |
| FBXO2 | F-box protein 2 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FKBP5 | FK506 binding protein 5 |
| FMO4 | flavin containing monooxygenase 4 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| HIST1H1T | histone cluster 1, H1t |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H2AM | histone cluster 1, H2am |
| HIST1H3C | histone cluster 1, H3c |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| IL12A | interleukin 12A |
| IQCC | IQ motif containing C |
| KCTD15 | potassium channel tetramerization domain containing 15 |
| KIAA0754 | KIAA0754 |
| KIF13B | kinesin family member 13B |
| KLHL36 | kelch-like family member 36 |
| LOC257152 | uncharacterized LOC257152 |
| LRRC37A4P | leucine rich repeat containing 37, member A4, pseudogene |
| MED15 | mediator complex subunit 15 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MGC12488 | |
| MRPL46 | mitochondrial ribosomal protein L46 |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MUC3B | mucin 3B, cell surface associated |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NXPH4 | neurexophilin 4 |
| ODF2 | outer dense fiber of sperm tails 2 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PARM1 | prostate androgen-regulated mucin-like protein 1 |
| PLD3 | phospholipase D family, member 3 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PRR7 | proline rich 7 (synaptic) |
| PTK6 | protein tyrosine kinase 6 |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| QSER1 | glutamine and serine rich 1 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 |
| ROM1 | retinal outer segment membrane protein 1 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SLC12A8 | solute carrier family 12, member 8 |
| SLN | sarcolipin |
| SMARCB1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| SSBP3 | single stranded DNA binding protein 3 |
| STK25 | serine/threonine kinase 25 |
| THBS3 | thrombospondin 3 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| UNKL | unkempt family zinc finger-like |
| WDR33 | WD repeat domain 33 |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZDHHC18 | zinc finger, DHHC-type containing 18 |
| ZFP30 | ZFP30 zinc finger protein |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF415 | zinc finger protein 415 |
| ZNF446 | zinc finger protein 446 |
| ZNF76 | zinc finger protein 76 |
