| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the hyoscyamine-5524 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACRV1 | acrosomal vesicle protein 1 |
| ACVR1B | activin A receptor, type IB |
| ADGRL1 | adhesion G protein-coupled receptor L1 |
| APOE | apolipoprotein E |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BTG3 | BTG family, member 3 |
| C1QB | complement component 1, q subcomponent, B chain |
| C21ORF2 | chromosome 21 open reading frame 2 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
| CCDC71 | coiled-coil domain containing 71 |
| CD300C | CD300c molecule |
| CD53 | CD53 molecule |
| CNKSR2 | connector enhancer of kinase suppressor of Ras 2 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) |
| CPA4 | carboxypeptidase A4 |
| CST6 | cystatin E/M |
| CUL7 | cullin 7 |
| CYB561 | cytochrome b561 |
| CYP2W1 | cytochrome P450, family 2, subfamily W, polypeptide 1 |
| DIEXF | digestive organ expansion factor homolog (zebrafish) |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| DPP4 | dipeptidyl-peptidase 4 |
| EDNRA | endothelin receptor type A |
| ELOVL2 | ELOVL fatty acid elongase 2 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 |
| ERC2-IT1 | ERC2 intronic transcript 1 |
| FETUB | fetuin B |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FN1 | fibronectin 1 |
| FOXF1 | forkhead box F1 |
| FSCN3 | fascin actin-bundling protein 3, testicular |
| GGT1 | gamma-glutamyltransferase 1 |
| GLT8D2 | glycosyltransferase 8 domain containing 2 |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| GRIP2 | glutamate receptor interacting protein 2 |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HOXA2 | homeobox A2 |
| ICA1 | islet cell autoantigen 1, 69kDa |
| ICAM1 | intercellular adhesion molecule 1 |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| IRS2 | insulin receptor substrate 2 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| LATS1 | large tumor suppressor kinase 1 |
| LBX1 | ladybird homeobox 1 |
| LRP6 | low density lipoprotein receptor-related protein 6 |
| LUZP4 | leucine zipper protein 4 |
| MAPK8 | mitogen-activated protein kinase 8 |
| MDM4 | MDM4, p53 regulator |
| MED27 | mediator complex subunit 27 |
| MFAP2 | microfibrillar-associated protein 2 |
| MMP7 | matrix metallopeptidase 7 |
| MSR1 | macrophage scavenger receptor 1 |
| MTSS1L | metastasis suppressor 1-like |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NRN1 | neuritin 1 |
| NRSN2 | neurensin 2 |
| PCDHB3 | protocadherin beta 3 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PLSCR2 | phospholipid scramblase 2 |
| PON1 | paraoxonase 1 |
| POU5F1B | POU class 5 homeobox 1B |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PRKCH | protein kinase C, eta |
| PSG9 | pregnancy specific beta-1-glycoprotein 9 |
| PTCH2 | patched 2 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 |
| R3HDM1 | R3H domain containing 1 |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| REC8 | REC8 meiotic recombination protein |
| RPL10L | ribosomal protein L10-like |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| SELP | selectin P (granule membrane protein 140kDa, antigen CD62) |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SFTPB | surfactant protein B |
| SLC25A16 | solute carrier family 25 (mitochondrial carrier), member 16 |
| SPAG8 | sperm associated antigen 8 |
| SPG21 | spastic paraplegia 21 (autosomal recessive, Mast syndrome) |
| STRN3 | striatin, calmodulin binding protein 3 |
| STYK1 | serine/threonine/tyrosine kinase 1 |
| SYN2 | synapsin II |
| SYT11 | synaptotagmin XI |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TGFB2 | transforming growth factor, beta 2 |
| THRB | thyroid hormone receptor, beta |
| TMEM63A | transmembrane protein 63A |
| USP46 | ubiquitin specific peptidase 46 |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| VCAN | versican |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF516 | zinc finger protein 516 |
| ZNF747 | zinc finger protein 747 |
| ZYX | zyxin |
| Symbol | Name |
|---|---|
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) |
| ASCC2 | activating signal cointegrator 1 complex subunit 2 |
| ASTN2 | astrotactin 2 |
| AXIN1 | axin 1 |
| BCL9 | B-cell CLL/lymphoma 9 |
| BIRC7 | baculoviral IAP repeat containing 7 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CAPN5 | calpain 5 |
| CBX4 | chromobox homolog 4 |
| CDK20 | cyclin-dependent kinase 20 |
| CDON | cell adhesion associated, oncogene regulated |
| CHKB | choline kinase beta |
| CLDN9 | claudin 9 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CPSF3L | cleavage and polyadenylation specific factor 3-like |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| EFCAB2 | EF-hand calcium binding domain 2 |
| EFNA3 | ephrin-A3 |
| EPN3 | epsin 3 |
| EPPK1 | epiplakin 1 |
| ETNK2 | ethanolamine kinase 2 |
| EXOC5 | exocyst complex component 5 |
| F2R | coagulation factor II (thrombin) receptor |
| FAM110B | family with sequence similarity 110, member B |
| FUZ | fuzzy planar cell polarity protein |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HELZ | helicase with zinc finger |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2AL | histone cluster 1, H2al |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| INCENP | inner centromere protein antigens 135/155kDa |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LSR | lipolysis stimulated lipoprotein receptor |
| MAMLD1 | mastermind-like domain containing 1 |
| MANBA | mannosidase, beta A, lysosomal |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| NDRG1 | N-myc downstream regulated 1 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NHEJ1 | nonhomologous end-joining factor 1 |
| NLRX1 | NLR family member X1 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PCDHA9 | protocadherin alpha 9 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| PISD | phosphatidylserine decarboxylase |
| PLA2G3 | phospholipase A2, group III |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PTK6 | protein tyrosine kinase 6 |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RECQL4 | RecQ protein-like 4 |
| RFTN1 | raftlin, lipid raft linker 1 |
| ROM1 | retinal outer segment membrane protein 1 |
| SCAMP3 | secretory carrier membrane protein 3 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SPIDR | scaffolding protein involved in DNA repair |
| SRPX | sushi-repeat containing protein, X-linked |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STAG3 | stromal antigen 3 |
| SUSD4 | sushi domain containing 4 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TSC1 | tuberous sclerosis 1 |
| TSPAN1 | tetraspanin 1 |
| TSPAN15 | tetraspanin 15 |
| TTC30A | tetratricopeptide repeat domain 30A |
| TUBA3C | tubulin, alpha 3c |
| TUBA3D | tubulin, alpha 3d |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| XAB2 | XPA binding protein 2 |
| ZDHHC18 | zinc finger, DHHC-type containing 18 |
| ZDHHC24 | zinc finger, DHHC-type containing 24 |
| ZNF205 | zinc finger protein 205 |
| ZNF408 | zinc finger protein 408 |
| ZNF446 | zinc finger protein 446 |
| ZNF767P | zinc finger family member 767, pseudogene |
