hyperactive renin-angiotensin system Gene Set

Dataset HPO Gene-Disease Associations
Category disease or phenotype associations
Type phenotype
Description An abnormally increased activity of the renin-angiotensin system, causing hypertension by a combination of volume excess and vasoconstrictor mechanisms. (Human Phenotype Ontology, HP_0000841)
External Link http://compbio.charite.de/hpoweb/showterm?id=HP:0000841
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Genes

8 genes associated with the hyperactive renin-angiotensin system phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol Name
CLCNKB chloride channel, voltage-sensitive Kb
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
NR3C2 nuclear receptor subfamily 3, group C, member 2
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SCNN1B sodium channel, non voltage gated 1 beta subunit
SCNN1G sodium channel, non voltage gated 1 gamma subunit
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1
SLC26A3 solute carrier family 26 (anion exchanger), member 3
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