hyperactivity Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0001399
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Genes

288 gene mutations causing the hyperactivity phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AADAT aminoadipate aminotransferase
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABHD12 abhydrolase domain containing 12
ACP2 acid phosphatase 2, lysosomal
ACTL6B actin-like 6B
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
ADGRL3 adhesion G protein-coupled receptor L3
ADIPOR2 adiponectin receptor 2
AGRP agouti related neuropeptide
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B
AP3B2 adaptor-related protein complex 3, beta 2 subunit
AP3D1 adaptor-related protein complex 3, delta 1 subunit
APAF1 apoptotic peptidase activating factor 1
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
ARRDC3 arrestin domain containing 3
ARSA arylsulfatase A
ARX aristaless related homeobox
ATF2 activating transcription factor 2
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
ATPIF1 ATPase inhibitory factor 1
ATRN attractin
ATXN2 ataxin 2
B3GALT2 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
BACE1 beta-site APP-cleaving enzyme 1
BASP1 brain abundant, membrane attached signal protein 1
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BDNF brain-derived neurotrophic factor
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRPF1 bromodomain and PHD finger containing, 1
BTBD9 BTB (POZ) domain containing 9
C1QBP complement component 1, q subcomponent binding protein
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3
CACNG2 calcium channel, voltage-dependent, gamma subunit 2
CADPS2 Ca++-dependent secretion activator 2
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative)
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC101 coiled-coil domain containing 101
CCDC120 coiled-coil domain containing 120
CCDC7 coiled-coil domain containing 7
CCKAR cholecystokinin A receptor
CCKBR cholecystokinin B receptor
CDH23 cadherin-related 23
CDK4 cyclin-dependent kinase 4
CDKL5 cyclin-dependent kinase-like 5
CELF4 CUGBP, Elav-like family member 4
CERS1 ceramide synthase 1
CERS6 ceramide synthase 6
CES1 carboxylesterase 1
CHAT choline O-acetyltransferase
CHD7 chromodomain helicase DNA binding protein 7
CHRD chordin
CHRM1 cholinergic receptor, muscarinic 1
CHRM4 cholinergic receptor, muscarinic 4
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
CLCN3 chloride channel, voltage-sensitive 3
CLOCK clock circadian regulator
CNR1 cannabinoid receptor 1 (brain)
CNTNAP2 contactin associated protein-like 2
COQ9 coenzyme Q9
COX4I1 cytochrome c oxidase subunit IV isoform 1
CPLX2 complexin 2
CREM cAMP responsive element modulator
CRTC1 CREB regulated transcription coactivator 1
CSMD1 CUB and Sushi multiple domains 1
DCR Down syndrome chromosome region
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DFNB31 deafness, autosomal recessive 31
DGAT1 diacylglycerol O-acyltransferase 1
DISC1 disrupted in schizophrenia 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
DLL1 delta-like 1 (Drosophila)
DMBX1 diencephalon/mesencephalon homeobox 1
DRD1 dopamine receptor D1
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
DRD5 dopamine receptor D5
EIF4H eukaryotic translation initiation factor 4H
ELFN1 extracellular leucine-rich repeat and fibronectin type III domain containing 1
ELMOD1 ELMO/CED-12 domain containing 1
EN1 engrailed homeobox 1
EN2 engrailed homeobox 2
EPHB2 EPH receptor B2
ERBB4 erb-b2 receptor tyrosine kinase 4
ESR1 estrogen receptor 1
ESRP1 epithelial splicing regulatory protein 1
FABP7 fatty acid binding protein 7, brain
FAM117B family with sequence similarity 117, member B
FBXO11 F-box protein 11
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FEZF2 FEZ family zinc finger 2
FGF3 fibroblast growth factor 3
FHL1 four and a half LIM domains 1
FMR1 fragile X mental retardation 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXA2 forkhead box A2
FOXI1 forkhead box I1
FXR2 fragile X mental retardation, autosomal homolog 2
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GFI1 growth factor independent 1 transcription repressor
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLRA1 glycine receptor, alpha 1
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GNAS GNAS complex locus
GNG2 guanine nucleotide binding protein (G protein), gamma 2
GPR21 G protein-coupled receptor 21
GPR50 G protein-coupled receptor 50
GPR83 G protein-coupled receptor 83
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIA2 glutamate receptor, ionotropic, AMPA 2
GRIA4 glutamate receptor, ionotropic, AMPA 4
GRID2 glutamate receptor, ionotropic, delta 2
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRK6 G protein-coupled receptor kinase 6
GRM2 glutamate receptor, metabotropic 2
GRPR gastrin-releasing peptide receptor
GSE1 Gse1 coiled-coil protein
GSTM5 glutathione S-transferase mu 5
GTF2IRD1 GTF2I repeat domain containing 1
HDAC4 histone deacetylase 4
HFE hemochromatosis
HMX2 H6 family homeobox 2
HMX3 H6 family homeobox 3
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
HTT huntingtin
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IL6 interleukin 6
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1
KALRN kalirin, RhoGEF kinase
KANSL1 KAT8 regulatory NSL complex subunit 1
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KCNIP3 Kv channel interacting protein 3, calsenilin
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KLC2 kinesin light chain 2
LCLAT1 lysocardiolipin acyltransferase 1
LDLR low density lipoprotein receptor
LGALS8 lectin, galactoside-binding, soluble, 8
LIMK1 LIM domain kinase 1
LMO4 LIM domain only 4
LMX1A LIM homeobox transcription factor 1, alpha
LOC102723475 putative uncharacterized protein LOC388820
LPAR5 lysophosphatidic acid receptor 5
LRRC4 leucine rich repeat containing 4
LRRC7 leucine rich repeat containing 7
LRTOMT leucine rich transmembrane and O-methyltransferase domain containing
LSAMP limbic system-associated membrane protein
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAOB monoamine oxidase B
MAP6 microtubule-associated protein 6
MAPK3 mitogen-activated protein kinase 3
MAPT microtubule-associated protein tau
MARK4 MAP/microtubule affinity-regulating kinase 4
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MCHR1 melanin-concentrating hormone receptor 1
MCOLN3 mucolipin 3
MECP2 methyl CpG binding protein 2
MFSD2A major facilitator superfamily domain containing 2A
MGLL monoglyceride lipase
MID1 midline 1
MIR128-2 microRNA 128-2
MYO6 myosin VI
MYO7A myosin VIIA
NEUROD1 neuronal differentiation 1
NLGN3 neuroligin 3
NOX3 NADPH oxidase 3
NPAS3 neuronal PAS domain protein 3
NPAS4 neuronal PAS domain protein 4
NPY1R neuropeptide Y receptor Y1
NPY6R neuropeptide Y receptor Y6 (pseudogene)
NR1D2 nuclear receptor subfamily 1, group D, member 2
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
NRG1 neuregulin 1
NSUN2 NOP2/Sun RNA methyltransferase family, member 2
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OCA2 oculocutaneous albinism II
OPHN1 oligophrenin 1
OPRD1 opioid receptor, delta 1
OPRM1 opioid receptor, mu 1
OTC ornithine carbamoyltransferase
OTOG otogelin
OXTR oxytocin receptor
PCDH15 protocadherin-related 15
PDE11A phosphodiesterase 11A
PDE1B phosphodiesterase 1B, calmodulin-dependent
PITX3 paired-like homeodomain 3
PKD2L2 polycystic kidney disease 2-like 2
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLIN2 perilipin 2
PLIN5 perilipin 5
PNPLA6 patatin-like phospholipase domain containing 6
POMC proopiomelanocortin
POU4F3 POU class 4 homeobox 3
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PSAP prosaposin
PTPRF protein tyrosine phosphatase, receptor type, F
PTPRG protein tyrosine phosphatase, receptor type, G
RAD18 RAD18 E3 ubiquitin protein ligase
RGS4 regulator of G-protein signaling 4
RYR3 ryanodine receptor 3
SEPP1 selenoprotein P, plasma, 1
SETMAR SET domain and mariner transposase fusion gene
SH3KBP1 SH3-domain kinase binding protein 1
SHANK2 SH3 and multiple ankyrin repeat domains 2
SHANK3 SH3 and multiple ankyrin repeat domains 3
SIRT2 sirtuin 2
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC13A5 solute carrier family 13 (sodium-dependent citrate transporter), member 5
SLC17A8 solute carrier family 17 (vesicular glutamate transporter), member 8
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3
SLC25A38 solute carrier family 25, member 38
SLC45A2 solute carrier family 45, member 2
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 5
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6
SLITRK6 SLIT and NTRK-like family, member 6
SNAI2 snail family zinc finger 2
SNAP25 synaptosomal-associated protein, 25kDa
SOBP sine oculis binding protein homolog (Drosophila)
SP4 Sp4 transcription factor
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
SRR serine racemase
SSFA2 sperm specific antigen 2
STON2 stonin 2
STX1A syntaxin 1A (brain)
SYNGAP1 synaptic Ras GTPase activating protein 1
TAAR1 trace amine associated receptor 1
TACR1 tachykinin receptor 1
TBX10 T-box 10
TGFB1 transforming growth factor, beta 1
THRB thyroid hormone receptor, beta
TMEM189 transmembrane protein 189
TMOD2 tropomodulin 2 (neuronal)
TMUB1 transmembrane and ubiquitin-like domain containing 1
TNC tenascin C
TNIK TRAF2 and NCK interacting kinase
TOM1L2 target of myb1-like 2 (chicken)
TOR1A torsin family 1, member A (torsin A)
TPH2 tryptophan hydroxylase 2
TUBA1A tubulin, alpha 1a
TUBB2B tubulin, beta 2B class IIb
UNC5C unc-5 homolog C (C. elegans)
UNC79 unc-79 homolog (C. elegans)
USH1C Usher syndrome 1C (autosomal recessive, severe)
USH1G Usher syndrome 1G (autosomal recessive)
USP2 ubiquitin specific peptidase 2
USP42 ubiquitin specific peptidase 42
VGF VGF nerve growth factor inducible
VIM vimentin
VLDLR very low density lipoprotein receptor
WFS1 Wolfram syndrome 1 (wolframin)
ZDHHC17 zinc finger, DHHC-type containing 17
ZEB1 zinc finger E-box binding homeobox 1
ZIC2 Zic family member 2