hyperglycemia Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

726 genes co-occuring with the disease hyperglycemia in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
INS insulin 4.21581
GCG glucagon 2.86538
GCK glucokinase (hexokinase 4) 2.26534
INSR insulin receptor 2.20576
LEP leptin 2.1608
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 1.97363
SST somatostatin 1.92155
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 1.915
IRS1 insulin receptor substrate 1 1.88898
GIP gastric inhibitory polypeptide 1.82957
DPP4 dipeptidyl-peptidase 4 1.79706
PPARG peroxisome proliferator-activated receptor gamma 1.79616
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.78894
IGF1 insulin-like growth factor 1 (somatomedin C) 1.78714
ALB albumin 1.75641
SOD2 superoxide dismutase 2, mitochondrial 1.72958
IAPP islet amyloid polypeptide 1.67457
G6PC glucose-6-phosphatase, catalytic subunit 1.58582
CAT catalase 1.58448
PRG4 proteoglycan 4 1.56045
PPARA peroxisome proliferator-activated receptor alpha 1.54142
NOS3 nitric oxide synthase 3 (endothelial cell) 1.54054
HMX1 H6 family homeobox 1 1.52688
HK1 hexokinase 1 1.52424
GPX1 glutathione peroxidase 1 1.51984
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 1.51633
GCGR glucagon receptor 1.50711
LEPR leptin receptor 1.49482
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.49438
GPX5 glutathione peroxidase 5 1.48955
GPX4 glutathione peroxidase 4 1.48867
IRS2 insulin receptor substrate 2 1.47901
FOXO1 forkhead box O1 1.47682
GLP1R glucagon-like peptide 1 receptor 1.46276
PYGB phosphorylase, glycogen; brain 1.45133
ACE angiotensin I converting enzyme 1.45133
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 1.45001
PYGL phosphorylase, glycogen, liver 1.44738
RETN resistin 1.43771
CRP C-reactive protein, pentraxin-related 1.43727
POMC proopiomelanocortin 1.42849
PYGM phosphorylase, glycogen, muscle 1.41709
SREBF1 sterol regulatory element binding transcription factor 1 1.40439
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.40307
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 1.36989
HNF1A HNF1 homeobox A 1.36814
PPY pancreatic polypeptide 1.35899
HBA1 hemoglobin, alpha 1 1.32105
NPY neuropeptide Y 1.31624
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.31056
HBA2 hemoglobin, alpha 2 1.31013
PDX1 pancreatic and duodenal homeobox 1 1.29964
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.28654
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 1.26124
GHRL ghrelin/obestatin prepropeptide 1.25689
LPL lipoprotein lipase 1.24776
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 1.24732
FASN fatty acid synthase 1.2395
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.2395
APOB apolipoprotein B 1.22085
TXNIP thioredoxin interacting protein 1.21565
TNF tumor necrosis factor 1.20483
FBP1 fructose-1,6-bisphosphatase 1 1.20353
PTPN1 protein tyrosine phosphatase, non-receptor type 1 1.19877
FN1 fibronectin 1 1.19877
IL6 interleukin 6 1.17164
DNAH8 dynein, axonemal, heavy chain 8 1.17121
TGFB1 transforming growth factor, beta 1 1.16136
IGFBP1 insulin-like growth factor binding protein 1 1.14093
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.1312
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 1.12487
CCL2 chemokine (C-C motif) ligand 2 1.11772
COG2 component of oligomeric golgi complex 2 1.11435
NEUROG3 neurogenin 3 1.11141
MLXIPL MLX interacting protein-like 1.10763
ICAM1 intercellular adhesion molecule 1 1.10594
FGF21 fibroblast growth factor 21 1.09881
AGER advanced glycosylation end product-specific receptor 1.09125
AGRP agouti related neuropeptide 1.08286
SIRT1 sirtuin 1 1.07824
NEUROD1 neuronal differentiation 1 1.0648
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2 1.05639
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.04546
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.04462
JUN jun proto-oncogene 1.0442
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.04251
G6PD glucose-6-phosphate dehydrogenase 1.03956
PKLR pyruvate kinase, liver and RBC 1.03577
VCAM1 vascular cell adhesion molecule 1 1.02692
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 1.01638
LIPE lipase, hormone-sensitive 1.01132
GSR glutathione reductase 1.0109
RBP4 retinol binding protein 4, plasma 1.00837
IGF1R insulin-like growth factor 1 receptor 1.00246
NOX4 NADPH oxidase 4 1.00119
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 0.997814
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.994439
REN renin 0.994017
PKM pyruvate kinase, muscle 0.985164
IL1B interleukin 1, beta 0.9839
CRTC2 CREB regulated transcription coactivator 2 0.983057
UCP3 uncoupling protein 3 (mitochondrial, proton carrier) 0.976744
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.97212
NNT nicotinamide nucleotide transhydrogenase 0.966663
NAMPT nicotinamide phosphoribosyltransferase 0.962053
CCK cholecystokinin 0.959123
FOXM1 forkhead box M1 0.950769
HNF4A hepatocyte nuclear factor 4, alpha 0.945354
ADIPOR1 adiponectin receptor 1 0.945354
GLO1 glyoxalase I 0.930414
STAP2 signal transducing adaptor family member 2 0.925039
GHRH growth hormone releasing hormone 0.922149
GLS2 glutaminase 2 (liver, mitochondrial) 0.921736
GIPR gastric inhibitory polypeptide receptor 0.914315
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.913903
MAFA v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A 0.911845
SORD sorbitol dehydrogenase 0.904032
HMOX1 heme oxygenase 1 0.898282
ADIPOR2 adiponectin receptor 2 0.890078
VEGFA vascular endothelial growth factor A 0.889668
FFAR1 free fatty acid receptor 1 0.888438
GCKR glucokinase (hexokinase 4) regulator 0.888438
CD36 CD36 molecule (thrombospondin receptor) 0.886389
ALPL alkaline phosphatase, liver/bone/kidney 0.881472
ALPPL2 alkaline phosphatase, placental-like 2 0.878195
APOE apolipoprotein E 0.877376
ALPP alkaline phosphatase, placental 0.877376
GAL galanin/GMAP prepropeptide 0.861818
HNF1B HNF1 homeobox B 0.861409
IGFBP3 insulin-like growth factor binding protein 3 0.852402
BAX BCL2-associated X protein 0.850354
PAX4 paired box 4 0.840525
GGT1 gamma-glutamyltransferase 1 0.838476
TRH thyrotropin-releasing hormone 0.830689
ASRGL1 asparaginase like 1 0.827409
NR1H4 nuclear receptor subfamily 1, group H, member 4 0.826178
PFKM phosphofructokinase, muscle 0.820026
PYY peptide YY 0.818385
XBP1 X-box binding protein 1 0.817976
SCARB1 scavenger receptor class B, member 1 0.816745
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.816334
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 0.814283
MGAM maltase-glucoamylase 0.80936
CPT1A carnitine palmitoyltransferase 1A (liver) 0.804846
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 0.802385
NPS neuropeptide S 0.800744
TCF7 transcription factor 7 (T-cell specific, HMG-box) 0.799923
SCARB2 scavenger receptor class B, member 2 0.799513
SOCS3 suppressor of cytokine signaling 3 0.798692
MAPK8 mitogen-activated protein kinase 8 0.792541
MTNR1B melatonin receptor 1B 0.783116
CTGF connective tissue growth factor 0.783116
PARP1 poly (ADP-ribose) polymerase 1 0.782707
ZDHHC23 zinc finger, DHHC-type containing 23 0.78066
EDN1 endothelin 1 0.778204
BGLAP bone gamma-carboxyglutamate (gla) protein 0.773705
TLR4 toll-like receptor 4 0.770435
CD4 CD4 molecule 0.768801
NFE2L2 nuclear factor, erythroid 2-like 2 0.768801
DLL1 delta-like 1 (Drosophila) 0.751271
KNG1 kininogen 1 0.750457
SELE selectin E 0.75005
ACE2 angiotensin I converting enzyme 2 0.749237
SHBG sex hormone-binding globulin 0.748424
CRH corticotropin releasing hormone 0.74761
APOA1 apolipoprotein A-I 0.745985
KIAA1919 KIAA1919 0.735027
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.727738
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.724502
HAGH hydroxyacylglutathione hydrolase 0.722886
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.717232
GRP gastrin-releasing peptide 0.716828
AOC2 amine oxidase, copper containing 2 (retina-specific) 0.716425
GAST gastrin 0.714811
TKT transketolase 0.713601
LDLR low density lipoprotein receptor 0.708767
SREBF2 sterol regulatory element binding transcription factor 2 0.700722
FAM3B family with sequence similarity 3, member B 0.699116
NKX2-2 NK2 homeobox 2 0.69751
FN3K fructosamine 3 kinase 0.695905
PLG plasminogen 0.695504
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.693499
HK2 hexokinase 2 0.692697
NPPA natriuretic peptide A 0.690694
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.688692
TRIB3 tribbles pseudokinase 3 0.688692
ISL1 ISL LIM homeobox 1 0.687091
CREB1 cAMP responsive element binding protein 1 0.686291
PNLIP pancreatic lipase 0.684292
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.680697
AKT2 v-akt murine thymoma viral oncogene homolog 2 0.679898
IDE insulin-degrading enzyme 0.6791
AMY2A amylase, alpha 2A (pancreatic) 0.677903
CS citrate synthase 0.671527
ADRB3 adrenoceptor beta 3 0.66914
PC pyruvate carboxylase 0.664769
LAD1 ladinin 1 0.66199
PLAT plasminogen activator, tissue 0.661197
ERN1 endoplasmic reticulum to nucleus signaling 1 0.659215
ATF6 activating transcription factor 6 0.654858
GH1 growth hormone 1 0.654067
GYS2 glycogen synthase 2 (liver) 0.653671
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 0.652484
MC4R melanocortin 4 receptor 0.650113
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.647743
CNR1 cannabinoid receptor 1 (brain) 0.646953
MAPK3 mitogen-activated protein kinase 3 0.643009
TXN thioredoxin 0.640645
BDKRB1 bradykinin receptor B1 0.640251
IGF2 insulin-like growth factor 2 0.639463
ACLY ATP citrate lyase 0.639463
AOC3 amine oxidase, copper containing 3 0.635921
DNM1L dynamin 1-like 0.633563
NIN ninein (GSK3B interacting protein) 0.632777
F3 coagulation factor III (thromboplastin, tissue factor) 0.631205
BTC betacellulin 0.628457
APOC3 apolipoprotein C-III 0.628457
HSH2D hematopoietic SH2 domain containing 0.627672
FOS FBJ murine osteosarcoma viral oncogene homolog 0.626495
GANAB glucosidase, alpha; neutral AB 0.626495
PNPLA2 patatin-like phospholipase domain containing 2 0.623751
FABP4 fatty acid binding protein 4, adipocyte 0.618268
GSTA3 glutathione S-transferase alpha 3 0.612011
GSTA2 glutathione S-transferase alpha 2 0.610448
GSTA4 glutathione S-transferase alpha 4 0.609276
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) 0.608104
PTH parathyroid hormone 0.604201
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 0.60342
GSTA1 glutathione S-transferase alpha 1 0.60342
CHKB choline kinase beta 0.60264
LPA lipoprotein, Lp(a) 0.60108
SLC30A8 solute carrier family 30 (zinc transporter), member 8 0.59913
PTPRN protein tyrosine phosphatase, receptor type, N 0.598351
GJD2 gap junction protein, delta 2, 36kDa 0.594454
CAPN10 calpain 10 0.592895
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.592895
MMP9 matrix metallopeptidase 9 0.591337
DGAT1 diacylglycerol O-acyltransferase 1 0.590948
UNC13A unc-13 homolog A (C. elegans) 0.588222
SH2B1 SH2B adaptor protein 1 0.585108
G6PC2 glucose-6-phosphatase, catalytic, 2 0.584719
GANC glucosidase, alpha; neutral C 0.582384
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) 0.581217
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.579272
ACTB actin, beta 0.578106
CALCA calcitonin-related polypeptide alpha 0.573828
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.573828
CYBA cytochrome b-245, alpha polypeptide 0.573439
STK11 serine/threonine kinase 11 0.57305
SGK1 serum/glucocorticoid regulated kinase 1 0.572662
SIRPA signal-regulatory protein alpha 0.572662
DGKB diacylglycerol kinase, beta 90kDa 0.572273
ANXA5 annexin A5 0.571884
STX4 syntaxin 4 0.571495
VWF von Willebrand factor 0.569941
GHSR growth hormone secretagogue receptor 0.562169
NGF nerve growth factor (beta polypeptide) 0.559839
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 0.55945
GPR83 G protein-coupled receptor 83 0.555956
DDIT3 DNA-damage-inducible transcript 3 0.55518
AVP arginine vasopressin 0.554403
CORT cortistatin 0.554015
THBS1 thrombospondin 1 0.553627
AGMO alkylglycerol monooxygenase 0.552075
ETV3 ets variant 3 0.551686
PCSK1 proprotein convertase subtilisin/kexin type 1 0.550522
ATG7 autophagy related 7 0.550134
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.547032
ACTG1 actin gamma 1 0.547032
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1 0.54393
NTS neurotensin 0.54393
SLC5A4 solute carrier family 5 (glucose activated ion channel), member 4 0.543542
CABIN1 calcineurin binding protein 1 0.541217
TFAM transcription factor A, mitochondrial 0.537344
MMP2 matrix metallopeptidase 2 0.536957
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.534635
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 0.534248
FTH1 ferritin, heavy polypeptide 1 0.526518
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 0.524974
UNC13B unc-13 homolog B (C. elegans) 0.51919
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast) 0.518034
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.516879
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.51611
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 0.51534
FTL ferritin, light polypeptide 0.514956
TBC1D4 TBC1 domain family, member 4 0.513417
VIP vasoactive intestinal peptide 0.509576
MLX MLX, MAX dimerization protein 0.508808
BDNF brain-derived neurotrophic factor 0.508424
PYCR1 pyrroline-5-carboxylate reductase 1 0.507657
PTPRD protein tyrosine phosphatase, receptor type, D 0.503441
RPS6 ribosomal protein S6 0.502292
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.501527
CSN1S1 casein alpha s1 0.501527
ALLC allantoicase 0.500761
PON1 paraoxonase 1 0.498085
FTO fat mass and obesity associated 0.496939
ILDR2 immunoglobulin-like domain containing receptor 2 0.494648
PAX3 paired box 3 0.49274
FURIN furin (paired basic amino acid cleaving enzyme) 0.492359
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 0.490835
PCTP phosphatidylcholine transfer protein 0.490454
SYT7 synaptotagmin VII 0.490072
PAX6 paired box 6 0.487407
PRL prolactin 0.484364
NOS2 nitric oxide synthase 2, inducible 0.483604
NOX1 NADPH oxidase 1 0.483604
FOXP2 forkhead box P2 0.483224
HMGB1 high mobility group box 1 0.482844
TLR2 toll-like receptor 2 0.481325
FADS1 fatty acid desaturase 1 0.480566
CAV1 caveolin 1, caveolae protein, 22kDa 0.478668
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.478289
PRKCE protein kinase C, epsilon 0.476014
SCN2A sodium channel, voltage gated, type II alpha subunit 0.466928
SLC5A11 solute carrier family 5 (sodium/inositol cotransporter), member 11 0.46655
DOC2B double C2-like domains, beta 0.465416
TAC1 tachykinin, precursor 1 0.46466
MLN motilin 0.463149
NR0B2 nuclear receptor subfamily 0, group B, member 2 0.459373
DGAT2 diacylglycerol O-acyltransferase 2 0.459373
NKX6-1 NK6 homeobox 1 0.458996
TF transferrin 0.458996
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae) 0.458619
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.456355
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 0.452208
OCLN occludin 0.450701
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase 0.448064
GHR growth hormone receptor 0.447687
ZFP69 ZFP69 zinc finger protein 0.447311
SIDT2 SID1 transmembrane family, member 2 0.447311
CCDC141 coiled-coil domain containing 141 0.447311
DNTT DNA nucleotidylexotransferase 0.445052
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 0.4443
KCNIP3 Kv channel interacting protein 3, calsenilin 0.443923
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.443171
ACHE acetylcholinesterase (Yt blood group) 0.443171
F2 coagulation factor II (thrombin) 0.441666
GCLC glutamate-cysteine ligase, catalytic subunit 0.44129
PER2 period circadian clock 2 0.439034
GLP2R glucagon-like peptide 2 receptor 0.438658
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 0.438658
HCRT hypocretin (orexin) neuropeptide precursor 0.437906
MC3R melanocortin 3 receptor 0.437906
PTEN phosphatase and tensin homolog 0.437154
IL18 interleukin 18 0.437154
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.436026
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.434148
GPRC6A G protein-coupled receptor, class C, group 6, member A 0.432646
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.430017
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.429266
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.428891
OR1J1 olfactory receptor, family 1, subfamily J, member 1 0.42739
PLIN1 perilipin 1 0.42589
FOXP3 forkhead box P3 0.42589
KEAP1 kelch-like ECH-associated protein 1 0.42589
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.424389
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.424014
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.42364
SYTL4 synaptotagmin-like 4 0.423265
ATF4 activating transcription factor 4 0.420641
HAND2 heart and neural crest derivatives expressed 2 0.420266
HSPA4 heat shock 70kDa protein 4 0.419892
VPREB1 pre-B lymphocyte 1 0.418768
SLC2A12 solute carrier family 2 (facilitated glucose transporter), member 12 0.418019
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.418019
GLIS3 GLIS family zinc finger 3 0.414276
NR3C2 nuclear receptor subfamily 3, group C, member 2 0.413153
PPARD peroxisome proliferator-activated receptor delta 0.409787
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 0.409414
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.408666
MUL1 mitochondrial E3 ubiquitin protein ligase 1 0.407919
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.405678
NRF1 nuclear respiratory factor 1 0.404184
LPIN1 lipin 1 0.403811
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 0.402692
FN3KRP fructosamine 3 kinase related protein 0.400453
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium) 0.399707
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.399334
TCEAL8 transcription elongation factor A (SII)-like 8 0.398216
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.39598
RAB34 RAB34, member RAS oncogene family 0.394491
MNX1 motor neuron and pancreas homeobox 1 0.392257
NFIA nuclear factor I/A 0.391513
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 0.389653
H3F3B H3 histone, family 3B (H3.3B) 0.389281
H3F3A H3 histone, family 3A 0.389281
MTTP microsomal triglyceride transfer protein 0.388538
PRKCD protein kinase C, delta 0.388166
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1 0.387794
TTR transthyretin 0.386308
PLN phospholamban 0.385936
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.385193
MOGAT2 monoacylglycerol O-acyltransferase 2 0.384451
ADM adrenomedullin 0.379997
CCKAR cholecystokinin A receptor 0.379626
CP ceruloplasmin (ferroxidase) 0.378514
NFIB nuclear factor I/B 0.378514
NIT1 nitrilase 1 0.376661
PLA2G1B phospholipase A2, group IB (pancreas) 0.37592
RICTOR RPTOR independent companion of MTOR, complex 2 0.37592
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8 0.374809
LCAT lecithin-cholesterol acyltransferase 0.374809
SDC2 syndecan 2 0.371847
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.370737
MMD monocyte to macrophage differentiation-associated 0.370368
GATA4 GATA binding protein 4 0.369997
SPP1 secreted phosphoprotein 1 0.368888
BCHE butyrylcholinesterase 0.368149
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 0.366301
ADCY2 adenylate cyclase 2 (brain) 0.365932
ANGPTL3 angiopoietin-like 3 0.365562
SIK2 salt-inducible kinase 2 0.363347
LGALS12 lectin, galactoside-binding, soluble, 12 0.363347
FOXA2 forkhead box A2 0.36187
MFN2 mitofusin 2 0.360395
CMKLR1 chemerin chemokine-like receptor 1 0.360026
GYS1 glycogen synthase 1 (muscle) 0.358551
GJA1 gap junction protein, alpha 1, 43kDa 0.356341
CETP cholesteryl ester transfer protein, plasma 0.355972
FOXO6 forkhead box O6 0.355235
TH tyrosine hydroxylase 0.352659
GAN gigaxonin 0.352291
F7 coagulation factor VII (serum prothrombin conversion accelerator) 0.351187
GPR119 G protein-coupled receptor 119 0.35082
STXBP3 syntaxin binding protein 3 0.349717
S100B S100 calcium binding protein B 0.349349
LGALS4 lectin, galactoside-binding, soluble, 4 0.348246
HPSE heparanase 0.345308
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 0.344941
GPX3 glutathione peroxidase 3 0.34384
USF1 upstream transcription factor 1 0.343106
GGT2 gamma-glutamyltransferase 2 0.342372
TJP1 tight junction protein 1 0.341272
NES nestin 0.340906
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.340539
ITLN1 intelectin 1 (galactofuranose binding) 0.338707
TIMP1 TIMP metallopeptidase inhibitor 1 0.338707
PCNA proliferating cell nuclear antigen 0.338341
CD68 CD68 molecule 0.335778
PDPK1 3-phosphoinositide dependent protein kinase 1 0.335778
SP1 Sp1 transcription factor 0.33066
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 0.328105
OSBPL11 oxysterol binding protein-like 11 0.32774
PGF placental growth factor 0.325187
IL10 interleukin 10 0.324823
GPBAR1 G protein-coupled bile acid receptor 1 0.324458
BEND3 BEN domain containing 3 0.321545
SLC25A19 solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 0.318272
RPF2 ribosome production factor 2 homolog (S. cerevisiae) 0.317182
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial 0.316456
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 0.315729
ROCK1P1 Rho-associated, coiled-coil containing protein kinase 1 pseudogene 1 0.313552
FGF2 fibroblast growth factor 2 (basic) 0.313552
CREM cAMP responsive element modulator 0.311014
JAK2 Janus kinase 2 0.31029
AGTR1 angiotensin II receptor, type 1 0.307033
GLB1 galactosidase, beta 1 0.30631
MAPK9 mitogen-activated protein kinase 9 0.304142
G0S2 G0/G1 switch 2 0.300533
AQP7 aquaporin 7 0.298371
ACAT2 acetyl-CoA acetyltransferase 2 0.298371
NPR1 natriuretic peptide receptor 1 0.297651
GUCY2C guanylate cyclase 2C 0.296571
EDNRA endothelin receptor type A 0.295492
GAPT GRB2-binding adaptor protein, transmembrane 0.293694
ANGPT2 angiopoietin 2 0.293694
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 0.291898
LOXL2 lysyl oxidase-like 2 0.290821
MFN1 mitofusin 1 0.290821
TGM4 transglutaminase 4 0.290821
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 0.290462
SMAD2 SMAD family member 2 0.290103
CRY1 cryptochrome circadian clock 1 0.289027
MOGAT1 monoacylglycerol O-acyltransferase 1 0.288668
APOM apolipoprotein M 0.28831
SSTR5 somatostatin receptor 5 0.287952
RUNX2 runt-related transcription factor 2 0.283655
MPV17 MpV17 mitochondrial inner membrane protein 0.282582
ERO1LB ERO1-like beta (S. cerevisiae) 0.280082
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.280082
GSK3B glycogen synthase kinase 3 beta 0.278654
LYPLA1 lysophospholipase I 0.27794
GSK3A glycogen synthase kinase 3 alpha 0.277227
LIPC lipase, hepatic 0.27687
NFIC nuclear factor I/C (CCAAT-binding transcription factor) 0.276158
CANX calnexin 0.274021
NFIX nuclear factor I/X (CCAAT-binding transcription factor) 0.273664
MAPK14 mitogen-activated protein kinase 14 0.273664
CHAD chondroadherin 0.273308
KL klotho 0.272953
CD40LG CD40 ligand 0.271174
LDHA lactate dehydrogenase A 0.270108
MPO myeloperoxidase 0.270108
PTF1A pancreas specific transcription factor, 1a 0.269753
ESR1 estrogen receptor 1 0.268687
EPHX2 epoxide hydrolase 2, cytoplasmic 0.266558
PPP4C protein phosphatase 4, catalytic subunit 0.265494
IGLV2-8 immunoglobulin lambda variable 2-8 0.26514
HSPA1A heat shock 70kDa protein 1A 0.264431
TUBGCP3 tubulin, gamma complex associated protein 3 0.260184
MBOAT4 membrane bound O-acyltransferase domain containing 4 0.259477
MLYCD malonyl-CoA decarboxylase 0.259124
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 0.25877
SUCNR1 succinate receptor 1 0.257711
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 0.257005
DUOX1 dual oxidase 1 0.256299
CREBBP CREB binding protein 0.254536
CPT1C carnitine palmitoyltransferase 1C 0.253479
CDH5 cadherin 5, type 2 (vascular endothelium) 0.253479
SYNPO synaptopodin 0.251718
CYB5RL cytochrome b5 reductase-like 0.250311
F9 coagulation factor IX 0.24715
GLRX glutaredoxin (thioltransferase) 0.246799
ZNF347 zinc finger protein 347 0.245396
CSH2 chorionic somatomammotropin hormone 2 0.244696
MIOX myo-inositol oxygenase 0.243295
SMAD3 SMAD family member 3 0.241895
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium) 0.241196
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 0.239799
TAT tyrosine aminotransferase 0.239101
NMB neuromedin B 0.239101
FAAH fatty acid amide hydrolase 0.237706
DUOX2 dual oxidase 2 0.237357
DOCK7 dedicator of cytokinesis 7 0.237009
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.234573
DUSP6 dual specificity phosphatase 6 0.234225
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta 0.234225
PLSCR4 phospholipid scramblase 4 0.233878
ANGPTL4 angiopoietin-like 4 0.232489
ELANE elastase, neutrophil expressed 0.231448
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.230755
KAT2A K(lysine) acetyltransferase 2A 0.230063
PLTP phospholipid transfer protein 0.229716
INPPL1 inositol polyphosphate phosphatase-like 1 0.229716
SI sucrase-isomaltase (alpha-glucosidase) 0.227988
STXBP1 syntaxin binding protein 1 0.227297
CFD complement factor D (adipsin) 0.227297
PLIN2 perilipin 2 0.225229
WFS1 Wolfram syndrome 1 (wolframin) 0.225229
PTS 6-pyruvoyltetrahydropterin synthase 0.224196
NR1H2 nuclear receptor subfamily 1, group H, member 2 0.223853
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.223165
C2CD4B C2 calcium-dependent domain containing 4B 0.222479
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 0.222479
RAB3A RAB3A, member RAS oncogene family 0.22145
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 0.220424
RNF31 ring finger protein 31 0.220081
NWD1 NACHT and WD repeat domain containing 1 0.217693
CHD4 chromodomain helicase DNA binding protein 4 0.217012
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.217012
CCND2 cyclin D2 0.216332
TBK1 TANK-binding kinase 1 0.216332
NPC1L1 NPC1-like 1 0.214975
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) 0.214636
PTPN9 protein tyrosine phosphatase, non-receptor type 9 0.214636
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial 0.214297
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 0.211261
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 0.210253
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2 0.209248
C21ORF2 chromosome 21 open reading frame 2 0.20658
B2M beta-2-microglobulin 0.205585
BECN1 beclin 1, autophagy related 0.204263
THY1 Thy-1 cell surface antigen 0.203604
SLC30A10 solute carrier family 30, member 10 0.203604
RAP1B RAP1B, member of RAS oncogene family 0.203275
C6ORF25 chromosome 6 open reading frame 25 0.202618
MEX3C mex-3 RNA binding family member C 0.200656
IARS isoleucyl-tRNA synthetase 0.200656
OPA1 optic atrophy 1 (autosomal dominant) 0.199681
FBXL20 F-box and leucine-rich repeat protein 20 0.199033
CST3 cystatin C 0.199033
PLEK pleckstrin 0.198709
ACACA acetyl-CoA carboxylase alpha 0.198709
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 0.198709
EXOG endo/exonuclease (5'-3'), endonuclease G-like 0.198064
MMP1 matrix metallopeptidase 1 0.197742
GPR1 G protein-coupled receptor 1 0.19742
ADA adenosine deaminase 0.197099
HAS2 hyaluronan synthase 2 0.19582
CCR2 chemokine (C-C motif) receptor 2 0.1936
RHOQ ras homolog family member Q 0.1936
CAPNS1 calpain, small subunit 1 0.193285
MYO5A myosin VA (heavy chain 12, myoxin) 0.193285
PER1 period circadian clock 1 0.192031
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.191719
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.190476
DOC2A double C2-like domains, alpha 0.189244
RPTOR regulatory associated protein of MTOR, complex 1 0.187719
CCND1 cyclin D1 0.187719
GPR26 G protein-coupled receptor 26 0.187113
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.186811
BARHL2 BarH-like homeobox 2 0.185612
SETD7 SET domain containing (lysine methyltransferase) 7 0.182957
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.182957
MED1 mediator complex subunit 1 0.182086
AMY1C amylase, alpha 1C (salivary) 0.180652
AMY1B amylase, alpha 1B (salivary) 0.180652
AMY1A amylase, alpha 1A (salivary) 0.180652
CERS1 ceramide synthase 1 0.179802
KDR kinase insert domain receptor 0.179802
SPTA1 spectrin, alpha, erythrocytic 1 0.179239
CHGA chromogranin A 0.179239
TALDO1 transaldolase 1 0.17896
PIR pirin (iron-binding nuclear protein) 0.177851
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1 0.177301
CD59 CD59 molecule, complement regulatory protein 0.175947
TP53 tumor protein p53 0.175411
ATF2 activating transcription factor 2 0.175411
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 0.174093
CNOT2 CCR4-NOT transcription complex, subunit 2 0.174093
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 0.173057
OR2D2 olfactory receptor, family 2, subfamily D, member 2 0.172544
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.171785
SCG5 secretogranin V 0.171286
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.171286
CLIC2 chloride intracellular channel 2 0.171036
PLSCR3 phospholipid scramblase 3 0.171036
NEIL3 nei endonuclease VIII-like 3 (E. coli) 0.170054
IL1RN interleukin 1 receptor antagonist 0.169812
SLC27A1 solute carrier family 27 (fatty acid transporter), member 1 0.169812
SIRT6 sirtuin 6 0.169812
TRPV1 transient receptor potential cation channel, subfamily V, member 1 0.169571
RNF24 ring finger protein 24 0.168617
RTN4R reticulon 4 receptor 0.168617
ACPP acid phosphatase, prostate 0.168381
HPR haptoglobin-related protein 0.166319
YME1L1 YME1-like 1 ATPase 0.166319
SPHK1 sphingosine kinase 1 0.165435
HSDL1 hydroxysteroid dehydrogenase like 1 0.165435
GPR39 G protein-coupled receptor 39 0.165217
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) 0.164786
NMUR2 neuromedin U receptor 2 0.163938
DGKA diacylglycerol kinase, alpha 80kDa 0.163111
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 0.163111
SAR1A secretion associated, Ras related GTPase 1A 0.162707
SOX17 SRY (sex determining region Y)-box 17 0.162707
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) 0.162306
ADAM17 ADAM metallopeptidase domain 17 0.162109
BCL2L1 BCL2-like 1 0.161523
ELOVL6 ELOVL fatty acid elongase 6 0.161331
ATP1B4 ATPase, Na+/K+ transporting, beta 4 polypeptide 0.161139
LMNA lamin A/C 0.161139
RAP2B RAP2B, member of RAS oncogene family 0.160948
CDC5L cell division cycle 5-like 0.160021
FBXO32 F-box protein 32 0.160021
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 0.160021
HLA-C major histocompatibility complex, class I, C 0.159658
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.15948
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled 0.159302
RAB1B RAB1B, member RAS oncogene family 0.159124
SH2B2 SH2B adaptor protein 2 0.158434
NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit 0.158434
GIMAP5 GTPase, IMAP family member 5 0.158097
CD47 CD47 molecule 0.157929
BOK BCL2-related ovarian killer 0.157765
CISH cytokine inducible SH2-containing protein 0.157602
SCLY selenocysteine lyase 0.153006
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6 0.152594
COX6B2 cytochrome c oxidase subunit VIb polypeptide 2 (testis) 0.152536
NCOA5 nuclear receptor coactivator 5 0.151244
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 0.150754
ASIC3 acid sensing (proton gated) ion channel 3 0.150032
ADGRF5 adhesion G protein-coupled receptor F5 0.149947
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 0.146567
FAM64A family with sequence similarity 64, member A 0.146099
GFM2 G elongation factor, mitochondrial 2 0.145902
CCDC80 coiled-coil domain containing 80 0.145863
ARNTL aryl hydrocarbon receptor nuclear translocator-like 0.145537
TAS1R2 taste receptor, type 1, member 2 0.145372
IRG1 immunoresponsive 1 homolog (mouse) 0.145327
KIF12 kinesin family member 12 0.14531
RFX3 regulatory factor X, 3 (influences HLA class II expression) 0.145142
CHIA chitinase, acidic 0.145121
MTMR9 myotubularin related protein 9 0.145113
BRS3 bombesin-like receptor 3 0.144918
KLF3 Kruppel-like factor 3 (basic) 0.144906
PDE3B phosphodiesterase 3B, cGMP-inhibited 0.144686
RIMS2 regulating synaptic membrane exocytosis 2 0.144589
NR2C2 nuclear receptor subfamily 2, group C, member 2 0.144585
BRD2 bromodomain containing 2 0.144477
GGCT gamma-glutamylcyclotransferase 0.144443
SESN3 sestrin 3 0.144324
NAGK N-acetylglucosamine kinase 0.144193
NR1H3 nuclear receptor subfamily 1, group H, member 3 0.14404
NPAT nuclear protein, ataxia-telangiectasia locus 0.143919
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene 0.143896
RXFP4 relaxin/insulin-like family peptide receptor 4 0.143831
TPCN2 two pore segment channel 2 0.143807
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.143768
NSF N-ethylmaleimide-sensitive factor 0.143758
ACOX1 acyl-CoA oxidase 1, palmitoyl 0.143683
FNDC5 fibronectin type III domain containing 5 0.143637
INSL5 insulin-like 5 0.143637
TCF19 transcription factor 19 0.143574
ERO1L ERO1-like (S. cerevisiae) 0.143558
CERS6 ceramide synthase 6 0.143536
FGF16 fibroblast growth factor 16 0.143349
GFPT2 glutamine-fructose-6-phosphate transaminase 2 0.143343
ALX3 ALX homeobox 3 0.143314
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 0.143271
PRKX protein kinase, X-linked 0.143153
GUCA2B guanylate cyclase activator 2B (uroguanylin) 0.14314
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) 0.143022
USP2 ubiquitin specific peptidase 2 0.142878
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular) 0.142733
OXR1 oxidation resistance 1 0.142718
RGN regucalcin 0.142658
OXT oxytocin/neurophysin I prepropeptide 0.142596
DUSP9 dual specificity phosphatase 9 0.142493
REL v-rel avian reticuloendotheliosis viral oncogene homolog 0.142485
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 0.142477
RANBP3 RAN binding protein 3 0.142328
SFRP5 secreted frizzled-related protein 5 0.142234
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 0.142225
ACADL acyl-CoA dehydrogenase, long chain 0.142216
PLA2G16 phospholipase A2, group XVI 0.142172
GGTLC2 gamma-glutamyltransferase light chain 2 0.141749
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.141749
FOXD3 forkhead box D3 0.141729
MAP3K14 mitogen-activated protein kinase kinase kinase 14 0.141668
GPAM glycerol-3-phosphate acyltransferase, mitochondrial 0.141555
AFF2 AF4/FMR2 family, member 2 0.141513
TIPE2 TNF alpha induced protein 8 like 2 0.141513
MTF1 metal-regulatory transcription factor 1 0.141217
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled 0.141183