hyperglycemia Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0001559
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Genes

79 gene mutations causing the hyperglycemia phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADIPOQ adiponectin, C1Q and collagen domain containing
ADIPOR1 adiponectin receptor 1
ADIPOR2 adiponectin receptor 2
ADRA1B adrenoceptor alpha 1B
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALMS1 Alstrom syndrome protein 1
ANGPTL6 angiopoietin-like 6
ASIP agouti signaling protein
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit
CAV1 caveolin 1, caveolae protein, 22kDa
CDK4 cyclin-dependent kinase 4
CLOCK clock circadian regulator
COL5A3 collagen, type V, alpha 3
CPE carboxypeptidase E
CRH corticotropin releasing hormone
CRTC1 CREB regulated transcription coactivator 1
CTF1 cardiotrophin 1
CTSB cathepsin B
CTSS cathepsin S
CTSV cathepsin V
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
FGL1 fibrinogen-like 1
GCK glucokinase (hexokinase 4)
GHR growth hormone receptor
GIPR gastric inhibitory polypeptide receptor
GLIS3 GLIS family zinc finger 3
HNF1A HNF1 homeobox A
HPRT1 hypoxanthine phosphoribosyltransferase 1
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
IDE insulin-degrading enzyme
ILDR2 immunoglobulin-like domain containing receptor 2
INS insulin
INSL5 insulin-like 5
INSR insulin receptor
IRS2 insulin receptor substrate 2
LDLR low density lipoprotein receptor
LEP leptin
LEPR leptin receptor
LIPE lipase, hormone-sensitive
MC4R melanocortin 4 receptor
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MIR375 microRNA 375
MYD88 myeloid differentiation primary response 88
NCOA3 nuclear receptor coactivator 3
NEUROD1 neuronal differentiation 1
NKX2-2 NK2 homeobox 2
NMU neuromedin U
NPBWR1 neuropeptides B/W receptor 1
NPY1R neuropeptide Y receptor Y1
OCA2 oculocutaneous albinism II
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDCD1LG2 programmed cell death 1 ligand 2
PDX1 pancreatic and duodenal homeobox 1
PLSCR3 phospholipid scramblase 3
PPARG peroxisome proliferator-activated receptor gamma
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PTTG1 pituitary tumor-transforming 1
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RBM4 RNA binding motif protein 4
RBM4B RNA binding motif protein 4B
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SGMS1 sphingomyelin synthase 1
SH2B1 SH2B adaptor protein 1
SIM1 single-minded family bHLH transcription factor 1
SIRT3 sirtuin 3
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SQSTM1 sequestosome 1
STXBP3 syntaxin binding protein 3
TGM2 transglutaminase 2
TLR3 toll-like receptor 3
TRH thyrotropin-releasing hormone
WRN Werner syndrome, RecQ helicase-like