hyperhidrosis Gene Set

Dataset HPO Gene-Disease Associations
Category disease or phenotype associations
Type phenotype
Description Abnormal excessive perspiration (sweating). (Human Phenotype Ontology, HP_0000975)
External Link http://compbio.charite.de/hpoweb/showterm?id=HP:0000975
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Genes

88 genes associated with the hyperhidrosis phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol Name
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AIP aryl hydrocarbon receptor interacting protein
ASCL1 achaete-scute family bHLH transcription factor 1
BCL2 B-cell CLL/lymphoma 2
BCL6 B-cell CLL/lymphoma 6
BDNF brain-derived neurotrophic factor
BIRC3 baculoviral IAP repeat containing 3
BLM Bloom syndrome, RecQ helicase-like
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
CAV1 caveolin 1, caveolae protein, 22kDa
CLCF1 cardiotrophin-like cytokine factor 1
COL17A1 collagen, type XVII, alpha 1
COL6A1 collagen, type VI, alpha 1
COL6A2 collagen, type VI, alpha 2
COL6A3 collagen, type VI, alpha 3
CRLF1 cytokine receptor-like factor 1
CTC1 CTS telomere maintenance complex component 1
CUL4B cullin 4B
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DKC1 dyskeratosis congenita 1, dyskerin
DSG1 desmoglein 1
DST dystonin
EDN3 endothelin 3
FAM134B family with sequence similarity 134, member B
FGFR3 fibroblast growth factor receptor 3
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXP1 forkhead box P1
FUCA1 fucosidase, alpha-L- 1, tissue
GDNF glial cell derived neurotrophic factor
HEXB hexosaminidase B (beta polypeptide)
HINT1 histidine triad nucleotide binding protein 1
HLA-B major histocompatibility complex, class I, B
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMBS hydroxymethylbilane synthase
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IGHMBP2 immunoglobulin mu binding protein 2
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL12B interleukin 12B
ITGB4 integrin, beta 4
JAK2 Janus kinase 2
JUP junction plakoglobin
KIF1A kinesin family member 1A
KIF1B kinesin family member 1B
KRT1 keratin 1, type II
KRT14 keratin 14, type I
KRT16 keratin 16, type I
KRT17 keratin 17, type I
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
KRT9 keratin 9, type I
LAMA3 laminin, alpha 3
LAMB3 laminin, beta 3
LAMC2 laminin, gamma 2
LIFR leukemia inhibitory factor receptor alpha
MALT1 MALT1 paracaspase
MLX MLX, MAX dimerization protein
MPL MPL proto-oncogene, thrombopoietin receptor
NHP2 NHP2 ribonucleoprotein
NLRP3 NLR family, pyrin domain containing 3
NOP10 NOP10 ribonucleoprotein
PHOX2B paired-like homeobox 2b
PRNP prion protein
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RET ret proto-oncogene
RTEL1 regulator of telomere elongation helicase 1
SCN11A sodium channel, voltage gated, type XI alpha subunit
SCN9A sodium channel, voltage gated, type IX alpha subunit
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SLURP1 secreted LY6/PLAUR domain containing 1
SUCLG1 succinate-CoA ligase, alpha subunit
TAT tyrosine aminotransferase
TERC telomerase RNA component
TERT telomerase reverse transcriptase
THPO thrombopoietin
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TRPV3 transient receptor potential cation channel, subfamily V, member 3
USB1 U6 snRNA biogenesis 1
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
WNK1 WNK lysine deficient protein kinase 1
WNT10A wingless-type MMTV integration site family, member 10A
WRAP53 WD repeat containing, antisense to TP53