hyperinsulinemic hypoglycemia Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A carbohydrate metabolic disorder that involves low blood glucose resulting from an excess of insulin. (Human Disease Ontology, DOID_13317)
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Genes

68 genes co-occuring with the disease hyperinsulinemic hypoglycemia in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 2.26376
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 2.01978
INS insulin 2.01568
GCG glucagon 1.87148
GLUD1 glutamate dehydrogenase 1 1.78714
SST somatostatin 1.7355
PPY pancreatic polypeptide 1.52732
GCK glucokinase (hexokinase 4) 1.46583
GAST gastrin 1.26647
HADH hydroxyacyl-CoA dehydrogenase 1.26429
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12 1.16863
MEN1 multiple endocrine neoplasia I 1.03746
ABCC12 ATP-binding cassette, sub-family C (CFTR/MRP), member 12 0.94078
NRK Nik related kinase 0.936214
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.934556
HNF4A hepatocyte nuclear factor 4, alpha 0.787213
VIP vasoactive intestinal peptide 0.750864
GCKR glucokinase (hexokinase 4) regulator 0.698715
FOXA2 forkhead box A2 0.671527
GLP1R glucagon-like peptide 1 receptor 0.631598
HNF1A HNF1 homeobox A 0.626495
INSR insulin receptor 0.625711
ALG3 ALG3, alpha-1,3- mannosyltransferase 0.615921
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 0.578883
PDX1 pancreatic and duodenal homeobox 1 0.572273
ACAA2 acetyl-CoA acyltransferase 2 0.55518
TBC1D4 TBC1 domain family, member 4 0.543542
SPTA1 spectrin, alpha, erythrocytic 1 0.515725
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11 0.513417
CHGA chromogranin A 0.477909
IGF2 insulin-like growth factor 2 0.452208
IAPP islet amyloid polypeptide 0.42139
ENO2 enolase 2 (gamma, neuronal) 0.416896
PNMT phenylethanolamine N-methyltransferase 0.401945
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 0.39598
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 0.394863
GHRH growth hormone releasing hormone 0.380368
UCN3 urocortin 3 0.37592
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 0.374068
MPI mannose phosphate isomerase 0.365562
INSM2 insulinoma-associated 2 0.359657
GIP gastric inhibitory polypeptide 0.342006
POMC proopiomelanocortin 0.334681
SEL1L sel-1 suppressor of lin-12-like (C. elegans) 0.331391
MEA1 male-enhanced antigen 1 0.323365
SYP synaptophysin 0.307395
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 0.30342
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 0.302698
DGUOK deoxyguanosine kinase 0.297651
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 0.295851
STX8 syntaxin 8 0.283655
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.276514
AKT2 v-akt murine thymoma viral oncogene homolog 2 0.268687
NR0B1 nuclear receptor subfamily 0, group B, member 1 0.266203
GRP gastrin-releasing peptide 0.264785
SCG5 secretogranin V 0.245747
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 0.245046
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.229024
SEPT5 septin 5 0.204593
KMT2B lysine (K)-specific methyltransferase 2B 0.204263
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 0.203275
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 0.201635
CRHR2 corticotropin releasing hormone receptor 2 0.1936
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 0.187719
SNAP23 synaptosomal-associated protein, 23kDa 0.173832
PMM2 phosphomannomutase 2 0.172038
CALCA calcitonin-related polypeptide alpha 0.159838
SSTR1 somatostatin receptor 1 0.158266