Hyperkeratosis is thickening of the outer layer of the skin, the stratum corneum, which is composed of large, polyhedral, plate-like envelopes filled with keratin which are the dead cells that have migrated up from the stratum granulosum. (Human Phenotype Ontology, HP_0000962)
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8 genes co-occuring with the biological term hyperkeratosis in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.