hyperlipidemia Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Abnormally high level of lipids in blood.|Conditions with excess LIPIDS in the blood. (Experimental Factor Ontology, EFO_0003774)
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Genes

73 genes co-occuring with the biological term hyperlipidemia in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACSL3 acyl-CoA synthetase long-chain family member 3
ACSL5 acyl-CoA synthetase long-chain family member 5
ADIPOQ adiponectin, C1Q and collagen domain containing
ADRB3 adrenoceptor beta 3
AGER advanced glycosylation end product-specific receptor
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
APOA1 apolipoprotein A-I
APOA2 apolipoprotein A-II
APOA5 apolipoprotein A-V
APOB apolipoprotein B
APOC3 apolipoprotein C-III
APOE apolipoprotein E
AS3MT arsenite methyltransferase
C3 complement component 3
C5AR2 complement component 5a receptor 2
CCL2 chemokine (C-C motif) ligand 2
CCL5 chemokine (C-C motif) ligand 5
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD36 CD36 molecule (thrombospondin receptor)
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDH5 cadherin 5, type 2 (vascular endothelium)
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CETP cholesteryl ester transfer protein, plasma
CP ceruloplasmin (ferroxidase)
CPE carboxypeptidase E
CXCL12 chemokine (C-X-C motif) ligand 12
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ESR1 estrogen receptor 1
FABP2 fatty acid binding protein 2, intestinal
FABP4 fatty acid binding protein 4, adipocyte
FADS3 fatty acid desaturase 3
FN1 fibronectin 1
HAMP hepcidin antimicrobial peptide
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
IGF1 insulin-like growth factor 1 (somatomedin C)
IRS1 insulin receptor substrate 1
LCAT lecithin-cholesterol acyltransferase
LDLR low density lipoprotein receptor
LEP leptin
LPL lipoprotein lipase
MIR122 microRNA 122
MIR24-1 microRNA 24-1
MIR370 microRNA 370
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP3 matrix metallopeptidase 3
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
NAMPT nicotinamide phosphoribosyltransferase
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
OSBPL10 oxysterol binding protein-like 10
OSM oncostatin M
PCSK9 proprotein convertase subtilisin/kexin type 9
PNPLA2 patatin-like phospholipase domain containing 2
PON1 paraoxonase 1
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
REN renin
RETN resistin
RXRG retinoid X receptor, gamma
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SELE selectin E
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SREBF1 sterol regulatory element binding transcription factor 1
TNF tumor necrosis factor
TXNIP thioredoxin interacting protein
USF1 upstream transcription factor 1
VEGFA vascular endothelial growth factor A
VEGFB vascular endothelial growth factor B
XDH xanthine dehydrogenase