hypermethylated Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

104 genes co-occuring with the biological term hypermethylated in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
APC adenomatous polyposis coli
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
CAV1 caveolin 1, caveolae protein, 22kDa
CCND1 cyclin D1
CCND2 cyclin D2
CD44 CD44 molecule (Indian blood group)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CHD4 chromodomain helicase DNA binding protein 4
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
CRABP1 cellular retinoic acid binding protein 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DACH1 dachshund family transcription factor 1
DAPK1 death-associated protein kinase 1
DDAH2 dimethylarginine dimethylaminohydrolase 2
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DUSP1 dual specificity phosphatase 1
E2F1 E2F transcription factor 1
EDA ectodysplasin A
EGFR epidermal growth factor receptor
EMP3 epithelial membrane protein 3
ENSA endosulfine alpha
ERBB2 erb-b2 receptor tyrosine kinase 2
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FBN1 fibrillin 1
FGF12 fibroblast growth factor 12
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GPC1 glypican 1
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GSTP1 glutathione S-transferase pi 1
HDAC1 histone deacetylase 1
HES5 hes family bHLH transcription factor 5
HOXA5 homeobox A5
HOXA6 homeobox A6
HOXA9 homeobox A9
HOXB5 homeobox B5
HRAS Harvey rat sarcoma viral oncogene homolog
IGF2 insulin-like growth factor 2
IGFBP3 insulin-like growth factor binding protein 3
IHH indian hedgehog
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KLF6 Kruppel-like factor 6
KMT2A lysine (K)-specific methyltransferase 2A
LARP1B La ribonucleoprotein domain family, member 1B
LRP1B low density lipoprotein receptor-related protein 1B
MBD2 methyl-CpG binding domain protein 2
MBD4 methyl-CpG binding domain protein 4
MGMT O-6-methylguanine-DNA methyltransferase
MIR125B1 microRNA 125b-1
MIR224 microRNA 224
MIR34A microRNA 34a
MIR34C microRNA 34c
MIR452 microRNA 452
MIR9-1 microRNA 9-1
MIR9-3 microRNA 9-3
MLH1 mutL homolog 1
MSH2 mutS homolog 2
MT1G metallothionein 1G
MYLK myosin light chain kinase
NEFL neurofilament, light polypeptide
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOTCH3 notch 3
PDGFA platelet-derived growth factor alpha polypeptide
PHOX2B paired-like homeobox 2b
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PRMT1 protein arginine methyltransferase 1
PROX1 prospero homeobox 1
PTEN phosphatase and tensin homolog
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRO protein tyrosine phosphatase, receptor type, O
RARB retinoic acid receptor, beta
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RASSF10 Ras association (RalGDS/AF-6) domain family (N-terminal) member 10
SALL2 spalt-like transcription factor 2
SCGB3A1 secretoglobin, family 3A, member 1
SCNN1B sodium channel, non voltage gated 1 beta subunit
SDC2 syndecan 2
SFN stratifin
SFRP1 secreted frizzled-related protein 1
SIRT1 sirtuin 1
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SNCG synuclein, gamma (breast cancer-specific protein 1)
SOCS1 suppressor of cytokine signaling 1
SPINT2 serine peptidase inhibitor, Kunitz type, 2
STC2 stanniocalcin 2
SYT6 synaptotagmin VI
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFAP2E transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)
TFPI2 tissue factor pathway inhibitor 2
TGM2 transglutaminase 2
TIMP2 TIMP metallopeptidase inhibitor 2
TJP1 tight junction protein 1
TMEFF2 transmembrane protein with EGF-like and two follistatin-like domains 2
TOX2 TOX high mobility group box family member 2
TP53 tumor protein p53
TTC12 tetratricopeptide repeat domain 12
VIM vimentin