hyperpigmentation Gene Set

Dataset	MPO Gene-Phenotype Associations
Category	disease or phenotype associations
Type	phenotype
Description	excess of pigment in any or all tissues or a part of a tissue (Mammalian Phenotype Ontology, MP_0001188)
External Link	http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0001188
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Genes

21 gene mutations causing the hyperpigmentation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol	Name
ACD	adrenocortical dysplasia homolog (mouse)
CBL	Cbl proto-oncogene, E3 ubiquitin protein ligase
DRD2	dopamine receptor D2
EGFR	epidermal growth factor receptor
GNA11	guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNAQ	guanine nucleotide binding protein (G protein), q polypeptide
GRM1	glutamate receptor, metabotropic 1
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG	KIT ligand
KRT1	keratin 1, type II
KRT2	keratin 2, type II
KRT9	keratin 9, type I
MC1R	melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MDM2	MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4	MDM4, p53 regulator
PRKDC	protein kinase, DNA-activated, catalytic polypeptide
RPL27A	ribosomal protein L27a
RPS19	ribosomal protein S19
RPS20	ribosomal protein S20
RUNDC1	RUN domain containing 1
TP53	tumor protein p53