hyperplastic Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description An abnormal increase in the number of cells in an organ or a tissue with consequent enlargement.|An abnormal increase in the number of (otherwise normal) cells in an organ or a tissue with consequent enlargement. (Experimental Factor Ontology, EFO_0000536)
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Genes

109 genes co-occuring with the biological term hyperplastic in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABI1 abl-interactor 1
ACP5 acid phosphatase 5, tartrate resistant
ACPP acid phosphatase, prostate
AIP aryl hydrocarbon receptor interacting protein
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALK anaplastic lymphoma receptor tyrosine kinase
ALOX5 arachidonate 5-lipoxygenase
AQP3 aquaporin 3 (Gill blood group)
AQP4 aquaporin 4
BAD BCL2-associated agonist of cell death
BAG1 BCL2-associated athanogene
BCL2 B-cell CLL/lymphoma 2
BIRC5 baculoviral IAP repeat containing 5
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA2 breast cancer 2, early onset
CALCA calcitonin-related polypeptide alpha
CCL21 chemokine (C-C motif) ligand 21
CD24 CD24 molecule
CD44 CD44 molecule (Indian blood group)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHGA chromogranin A
CLCA1 chloride channel accessory 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSE cathepsin E
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DMBT1 deleted in malignant brain tumors 1
EDN1 endothelin 1
EGFR epidermal growth factor receptor
EPCAM epithelial cell adhesion molecule
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FGF23 fibroblast growth factor 23
FGFR1 fibroblast growth factor receptor 1
FGFR3 fibroblast growth factor receptor 3
FH fumarate hydratase
FLCN folliculin
GAST gastrin
GH1 growth hormone 1
GLP1R glucagon-like peptide 1 receptor
GRM1 glutamate receptor, metabotropic 1
GSTP1 glutathione S-transferase pi 1
HMOX1 heme oxygenase 1
HYAL1 hyaluronoglucosaminidase 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFITM5 interferon induced transmembrane protein 5
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
INHBA inhibin, beta A
INHBB inhibin, beta B
INS insulin
INSL3 insulin-like 3 (Leydig cell)
IRF3 interferon regulatory factor 3
IRF7 interferon regulatory factor 7
KL klotho
KLK3 kallikrein-related peptidase 3
KRAS Kirsten rat sarcoma viral oncogene homolog
LGALS8 lectin, galactoside-binding, soluble, 8
LIPC lipase, hepatic
LTC4S leukotriene C4 synthase
MCL1 myeloid cell leukemia 1
MEN1 multiple endocrine neoplasia I
MIR181B1 microRNA 181b-1
MIR181B2 microRNA 181b-2
MIR21 microRNA 21
MIR375 microRNA 375
MIRLET7A1 microRNA let-7a-1
MKI67 marker of proliferation Ki-67
MLH1 mutL homolog 1
MSH2 mutS homolog 2
MUC1 mucin 1, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC6 mucin 6, oligomeric mucus/gel-forming
MUTYH mutY homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NAPSA napsin A aspartic peptidase
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NKX2-1 NK2 homeobox 1
NOS2 nitric oxide synthase 2, inducible
NR4A2 nuclear receptor subfamily 4, group A, member 2
PADI2 peptidyl arginine deiminase, type II
PADI4 peptidyl arginine deiminase, type IV
PCP4 Purkinje cell protein 4
PDGFB platelet-derived growth factor beta polypeptide
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
SFRP1 secreted frizzled-related protein 1
SHH sonic hedgehog
SMAD4 SMAD family member 4
SOCS2 suppressor of cytokine signaling 2
SUFU suppressor of fused homolog (Drosophila)
TFF1 trefoil factor 1
TFR2 transferrin receptor 2
TGFB1 transforming growth factor, beta 1
TP53 tumor protein p53
TP63 tumor protein p63
TRPM7 transient receptor potential cation channel, subfamily M, member 7
VEGFA vascular endothelial growth factor A
VTCN1 V-set domain containing T cell activation inhibitor 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
YAP1 Yes-associated protein 1
ZBTB7A zinc finger and BTB domain containing 7A