hyperprolactinemia Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description An acquired metabolic disease that has_material_basis_in the presence of abnormally-high levels of prolactin in the blood. (Human Disease Ontology, DOID_12700)
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Genes

85 genes co-occuring with the disease hyperprolactinemia in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
PRL prolactin 3.86286
TRH thyrotropin-releasing hormone 2.48317
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 2.15924
PRLR prolactin receptor 1.7709
POMC proopiomelanocortin 1.76185
CNTN5 contactin 5 1.6624
DRD2 dopamine receptor D2 1.52512
IGF1 insulin-like growth factor 1 (somatomedin C) 1.44694
GHRH growth hormone releasing hormone 1.32934
SHBG sex hormone-binding globulin 1.28654
VIP vasoactive intestinal peptide 1.16179
TH tyrosine hydroxylase 1.15198
INS insulin 1.10804
SST somatostatin 1.0362
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 0.927932
MEN1 multiple endocrine neoplasia I 0.91308
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 0.911022
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 0.843392
CLEC17A C-type lectin domain family 17, member A 0.813462
SHFM1 split hand/foot malformation (ectrodactyly) type 1 0.718846
PTH parathyroid hormone 0.718443
CRH corticotropin releasing hormone 0.690293
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 0.633956
CSH2 chorionic somatomammotropin hormone 2 0.613183
STAT5B signal transducer and activator of transcription 5B 0.607714
SMR3A submaxillary gland androgen regulated protein 3A 0.562558
UFC1 ubiquitin-fold modifier conjugating enzyme 1 0.558285
LEP leptin 0.549359
OXT oxytocin/neurophysin I prepropeptide 0.547807
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 0.534635
GNRHR gonadotropin-releasing hormone receptor 0.509576
AVP arginine vasopressin 0.508808
MCEE methylmalonyl CoA epimerase 0.50689
GAL galanin/GMAP prepropeptide 0.501527
GH1 growth hormone 1 0.472225
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 0.46655
BGLAP bone gamma-carboxyglutamate (gla) protein 0.465038
ANKRD54 ankyrin repeat domain 54 0.421016
GAST gastrin 0.404557
TRPC6 transient receptor potential cation channel, subfamily C, member 6 0.401945
DACT2 dishevelled-binding antagonist of beta-catenin 2 0.395235
MEA1 male-enhanced antigen 1 0.389281
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 0.379256
TSHB thyroid stimulating hormone, beta 0.37629
PRLH prolactin releasing hormone 0.373328
MGP matrix Gla protein 0.36704
RAB3D RAB3D, member RAS oncogene family 0.356341
AR androgen receptor 0.355972
ABAT 4-aminobutyrate aminotransferase 0.355972
CYP2D7 cytochrome P450, family 2, subfamily D, polypeptide 7 (gene/pseudogene) 0.350084
LALBA lactalbumin, alpha- 0.346777
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 0.340173
C11ORF31 chromosome 11 open reading frame 31 0.338707
GCG glucagon 0.333583
MUL1 mitochondrial E3 ubiquitin protein ligase 1 0.331025
SOCS3 suppressor of cytokine signaling 3 0.326281
NPY neuropeptide Y 0.326281
TAC1 tachykinin, precursor 1 0.318635
JAK2 Janus kinase 2 0.318272
TNP2 transition protein 2 (during histone to protamine replacement) 0.31464
DRD3 dopamine receptor D3 0.306672
HRH2 histamine receptor H2 0.301254
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.298011
IRF1 interferon regulatory factor 1 0.28831
ESR1 estrogen receptor 1 0.283297
NPEPPS aminopeptidase puromycin sensitive 0.264785
GRHL1 grainyhead-like 1 (Drosophila) 0.261599
FOSL2 FOS-like antigen 2 0.245046
TNP1 transition protein 1 (during histone to protamine replacement) 0.245046
FSHR follicle stimulating hormone receptor 0.240497
NPS neuropeptide S 0.237009
CROCC ciliary rootlet coiled-coil, rootletin 0.232836
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 0.231102
PTHLH parathyroid hormone-like hormone 0.231102
TGOLN2 trans-golgi network protein 2 0.227988
PROP1 PROP paired-like homeobox 1 0.227642
CALCA calcitonin-related polypeptide alpha 0.22145
TXNL4B thioredoxin-like 4B 0.215314
CNOT1 CCR4-NOT transcription complex, subunit 1 0.189859
IGFBP3 insulin-like growth factor binding protein 3 0.188326
CNOT2 CCR4-NOT transcription complex, subunit 2 0.185612
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 0.185313
DBT dihydrolipoamide branched chain transacylase E2 0.174881
GRM2 glutamate receptor, metabotropic 2 0.165655
WDHD1 WD repeat and HMG-box DNA binding protein 1 0.160574