hypersensitivity Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description An immune system disease that is an exaggerated immune response to allergens, such as insect venom, dust mites, pollen, pet dander, drugs or some foods. (Human Disease Ontology, DOID_1205)
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Genes

37 genes associated with the disease hypersensitivity in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ACP1 acid phosphatase 1, soluble
ADRB2 adrenoceptor beta 2, surface
CCL2 chemokine (C-C motif) ligand 2
CCR2 chemokine (C-C motif) receptor 2
CD14 CD14 molecule
CYSLTR1 cysteinyl leukotriene receptor 1
FLG filaggrin
FNDC3A fibronectin type III domain containing 3A
GATA3 GATA binding protein 3
HCP5 HLA complex P5 (non-protein coding)
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
ICOS inducible T-cell co-stimulator
IL10 interleukin 10
IL10RA interleukin 10 receptor, alpha
IL18 interleukin 18
IL1B interleukin 1, beta
IRAK4 interleukin-1 receptor-associated kinase 4
IRF1 interferon regulatory factor 1
LY96 lymphocyte antigen 96
MBL2 mannose-binding lectin (protein C) 2, soluble
MYD88 myeloid differentiation primary response 88
NOD2 nucleotide-binding oligomerization domain containing 2
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
TGFB1 transforming growth factor, beta 1
TLR1 toll-like receptor 1
TLR10 toll-like receptor 10
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR6 toll-like receptor 6
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase