hypertensive Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

204 genes co-occuring with the biological term hypertensive in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ACE2 angiotensin I converting enzyme 2
ACKR3 atypical chemokine receptor 3
ADA adenosine deaminase
ADD1 adducin 1 (alpha)
ADD2 adducin 2 (beta)
ADIPOQ adiponectin, C1Q and collagen domain containing
ADM adrenomedullin
ADRA1A adrenoceptor alpha 1A
ADRB1 adrenoceptor beta 1
ADRB2 adrenoceptor beta 2, surface
ADRB3 adrenoceptor beta 3
ADRBK1 adrenergic, beta, receptor kinase 1
AGER advanced glycosylation end product-specific receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AGTR2 angiotensin II receptor, type 2
ALPL alkaline phosphatase, liver/bone/kidney
ANXA5 annexin A5
APLN apelin
APLNR apelin receptor
APOB apolipoprotein B
APOC3 apolipoprotein C-III
APOE apolipoprotein E
AQP2 aquaporin 2 (collecting duct)
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
AVP arginine vasopressin
B2M beta-2-microglobulin
BBC3 BCL2 binding component 3
BDKRB2 bradykinin receptor B2
BMP4 bone morphogenetic protein 4
BMP5 bone morphogenetic protein 5
BMP7 bone morphogenetic protein 7
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
C1QTNF1 C1q and tumor necrosis factor related protein 1
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CAT catalase
CCL2 chemokine (C-C motif) ligand 2
CCL4 chemokine (C-C motif) ligand 4
CCR2 chemokine (C-C motif) receptor 2
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CETP cholesteryl ester transfer protein, plasma
CHGA chromogranin A
CLU clusterin
COL3A1 collagen, type III, alpha 1
CPB2 carboxypeptidase B2 (plasma)
CRP C-reactive protein, pentraxin-related
CTF1 cardiotrophin 1
CTGF connective tissue growth factor
CXCL12 chemokine (C-X-C motif) ligand 12
CYBA cytochrome b-245, alpha polypeptide
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1
DDAH1 dimethylarginine dimethylaminohydrolase 1
EDN1 endothelin 1
EDNRA endothelin receptor type A
EDNRB endothelin receptor type B
ENPEP glutamyl aminopeptidase (aminopeptidase A)
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
F3 coagulation factor III (thromboplastin, tissue factor)
F5 coagulation factor V (proaccelerin, labile factor)
FAAH fatty acid amide hydrolase
FAS Fas cell surface death receptor
FASN fatty acid synthase
FGF1 fibroblast growth factor 1 (acidic)
FGF23 fibroblast growth factor 23
FLT1 fms-related tyrosine kinase 1
GCH1 GTP cyclohydrolase 1
GDF15 growth differentiation factor 15
GGT1 gamma-glutamyltransferase 1
GHRL ghrelin/obestatin prepropeptide
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GPX1 glutathione peroxidase 1
GRK4 G protein-coupled receptor kinase 4
GSTM1 glutathione S-transferase mu 1
HAVCR1 hepatitis A virus cellular receptor 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMGA1 high mobility group AT-hook 1
HMOX1 heme oxygenase 1
HOXA9 homeobox A9
HP haptoglobin
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HSPA8 heat shock 70kDa protein 8
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
ICAM1 intercellular adhesion molecule 1
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IL1B interleukin 1, beta
IL6 interleukin 6
IL6ST interleukin 6 signal transducer
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KYNU kynureninase
LCN2 lipocalin 2
LEP leptin
LEPR leptin receptor
LOX lysyl oxidase
LPA lipoprotein, Lp(a)
LPL lipoprotein lipase
LRP6 low density lipoprotein receptor-related protein 6
MAPK14 mitogen-activated protein kinase 14
MBL2 mannose-binding lectin (protein C) 2, soluble
MGP matrix Gla protein
MIR126 microRNA 126
MIR9-2 microRNA 9-2
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTNR1A melatonin receptor 1A
MYH9 myosin, heavy chain 9, non-muscle
NAMPT nicotinamide phosphoribosyltransferase
NCAM1 neural cell adhesion molecule 1
NLRP6 NLR family, pyrin domain containing 6
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOX4 NADPH oxidase 4
NPFF neuropeptide FF-amide peptide precursor
NPPA natriuretic peptide A
NPPB natriuretic peptide B
NPR1 natriuretic peptide receptor 1
NPR3 natriuretic peptide receptor 3
NPY neuropeptide Y
NR3C2 nuclear receptor subfamily 3, group C, member 2
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OSM oncostatin M
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PCSK9 proprotein convertase subtilisin/kexin type 9
PGF placental growth factor
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLAT plasminogen activator, tissue
PON1 paraoxonase 1
POSTN periostin, osteoblast specific factor
PPARG peroxisome proliferator-activated receptor gamma
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme
PRCP prolylcarboxypeptidase (angiotensinase C)
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PTGFR prostaglandin F receptor (FP)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH parathyroid hormone
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RBP4 retinol binding protein 4, plasma
REN renin
RETN resistin
RGS2 regulator of G-protein signaling 2
RHOA ras homolog family member A
RLN1 relaxin 1
RLN2 relaxin 2
RNLS renalase, FAD-dependent amine oxidase
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SCNN1B sodium channel, non voltage gated 1 beta subunit
SCNN1G sodium channel, non voltage gated 1 gamma subunit
SELE selectin E
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SGK1 serum/glucocorticoid regulated kinase 1
SLC22A12 solute carrier family 22 (organic anion/urate transporter), member 12
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SOD1 superoxide dismutase 1, soluble
SPP1 secreted phosphoprotein 1
ST2 suppression of tumorigenicity 2
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TERT telomerase reverse transcriptase
TGFB1 transforming growth factor, beta 1
THBD thrombomodulin
THBS2 thrombospondin 2
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TLR4 toll-like receptor 4
TLR6 toll-like receptor 6
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TOR2A torsin family 2, member A
TRPC3 transient receptor potential cation channel, subfamily C, member 3
UTS2 urotensin 2
VASH1 vasohibin 1
VCAM1 vascular cell adhesion molecule 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VIPR2 vasoactive intestinal peptide receptor 2
VWF von Willebrand factor
WNK4 WNK lysine deficient protein kinase 4
XDH xanthine dehydrogenase