hypertriglyceridemia Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A condition of elevated levels of TRIGLYCERIDES in the blood. (Experimental Factor Ontology, EFO_0004211)
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Genes

74 genes co-occuring with the biological term hypertriglyceridemia in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACACA acetyl-CoA carboxylase alpha
ACAT1 acetyl-CoA acetyltransferase 1
ACE angiotensin I converting enzyme
ADRB2 adrenoceptor beta 2, surface
ANGPTL3 angiopoietin-like 3
ANGPTL4 angiopoietin-like 4
APOA1 apolipoprotein A-I
APOA2 apolipoprotein A-II
APOA5 apolipoprotein A-V
APOC1 apolipoprotein C-I
APOC2 apolipoprotein C-II
APOC3 apolipoprotein C-III
APOE apolipoprotein E
APOL1 apolipoprotein L, 1
BMP7 bone morphogenetic protein 7
C3 complement component 3
CAT catalase
CAV1 caveolin 1, caveolae protein, 22kDa
CD36 CD36 molecule (thrombospondin receptor)
CETP cholesteryl ester transfer protein, plasma
COL18A1 collagen, type XVIII, alpha 1
CREB3L3 cAMP responsive element binding protein 3-like 3
CRP C-reactive protein, pentraxin-related
CRTC3 CREB regulated transcription coactivator 3
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
F8 coagulation factor VIII, procoagulant component
FABP2 fatty acid binding protein 2, intestinal
FABP4 fatty acid binding protein 4, adipocyte
FOXO1 forkhead box O1
GAL galanin/GMAP prepropeptide
GCKR glucokinase (hexokinase 4) regulator
GK glycerol kinase
GPIHBP1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
GPX1 glutathione peroxidase 1
GSTM1 glutathione S-transferase mu 1
GSTT1 glutathione S-transferase theta 1
HFE hemochromatosis
ICAM1 intercellular adhesion molecule 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IL6 interleukin 6
INS insulin
INSIG1 insulin induced gene 1
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITLN1 intelectin 1 (galactofuranose binding)
LDLR low density lipoprotein receptor
LIPH lipase, member H
LMF1 lipase maturation factor 1
LPL lipoprotein lipase
MC4R melanocortin 4 receptor
MLXIPL MLX interacting protein-like
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTTP microsomal triglyceride transfer protein
NR0B1 nuclear receptor subfamily 0, group B, member 1
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
PLTP phospholipid transfer protein
PON1 paraoxonase 1
PPARA peroxisome proliferator-activated receptor alpha
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
RBP4 retinol binding protein 4, plasma
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SDC1 syndecan 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2
SLC25A40 solute carrier family 25, member 40
SOD2 superoxide dismutase 2, mitochondrial
SREBF1 sterol regulatory element binding transcription factor 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TIMD4 T-cell immunoglobulin and mucin domain containing 4
TRIB3 tribbles pseudokinase 3
VCAM1 vascular cell adhesion molecule 1
VWF von Willebrand factor