hypopituitarism Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description Diminution or cessation of secretion of one or more hormones from the anterior pituitary gland (including LH; FOLLICLE STIMULATING HORMONE; SOMATOTROPIN; and CORTICOTROPIN). This may result from surgical or radiation ablation, non-secretory PITUITARY NEOPLASMS, metastatic tumors, infarction, PITUITARY APOPLEXY, infiltrative or granulomatous processes, and other conditions.|A condition of diminution or cessation of secretion of one or more hormones from the anterior pituitary gland. This may result from surgical or radiation ablation, non-secretory pituitary neoplasms, metastatic tumors, infarction, pituitary apoplexy, infiltrative or granulomatous processes, and other conditions. (Experimental Factor Ontology, EFO_0001380)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003348
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Genes

3 gene mutations causing the hypopituitarism phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
APOE apolipoprotein E
PROP1 PROP paired-like homeobox 1
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3