hypothyroidism Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A deficiency of thyroid hormone. (Experimental Factor Ontology, EFO_0004705)
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Genes

65 genes co-occuring with the biological term hypothyroidism in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ALAD aminolevulinate dehydratase
CGA glycoprotein hormones, alpha polypeptide
CPB2 carboxypeptidase B2 (plasma)
CRP C-reactive protein, pentraxin-related
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL9 chemokine (C-X-C motif) ligand 9
DIO2 deiodinase, iodothyronine, type II
DUOX2 dual oxidase 2
DUOXA2 dual oxidase maturation factor 2
FGF21 fibroblast growth factor 21
FOXE1 forkhead box E1
FSHR follicle stimulating hormone receptor
FTH1 ferritin, heavy polypeptide 1
GHRL ghrelin/obestatin prepropeptide
GNAS GNAS complex locus
GSTO2 glutathione S-transferase omega 2
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP1 insulin-like growth factor binding protein 1
IGFBP3 insulin-like growth factor binding protein 3
IGSF1 immunoglobulin superfamily, member 1
IL4 interleukin 4
INHBB inhibin, beta B
INS insulin
IYD iodotyrosine deiodinase
LEP leptin
LRPAP1 low density lipoprotein receptor-related protein associated protein 1
NAMPT nicotinamide phosphoribosyltransferase
NCOR1 nuclear receptor corepressor 1
NKX2-1 NK2 homeobox 1
NOS2 nitric oxide synthase 2, inducible
PAX8 paired box 8
PDE8B phosphodiesterase 8B
PON1 paraoxonase 1
POU1F1 POU class 1 homeobox 1
PROP1 PROP paired-like homeobox 1
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRJ protein tyrosine phosphatase, receptor type, J
RBP4 retinol binding protein 4, plasma
REN renin
RETN resistin
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
SH2B3 SH2B adaptor protein 3
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFRC transferrin receptor
TG thyroglobulin
TGM1 transglutaminase 1
THBD thrombomodulin
THRA thyroid hormone receptor, alpha
THRB thyroid hormone receptor, beta
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNNT2 troponin T type 2 (cardiac)
TPO thyroid peroxidase
TRH thyrotropin-releasing hormone
TSHB thyroid stimulating hormone, beta
TSHR thyroid stimulating hormone receptor
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VAV3 vav 3 guanine nucleotide exchange factor