|Dataset||GO Biological Process Annotations|
|Category||structural or functional annotations|
|Description||A series of molecular signals mediated by hypoxia-inducible factor (HIF1) in response to lowered oxygen levels (hypoxia). Under hypoxic conditions, the oxygen-sensitive alpha-subunit of hypoxia-inducible factor (HIF)-1 dimerizes with a HIF1-beta subunit (also called ARNT or aryl-hydrocarbon-receptor nuclear translocator), translocates to the nucleus and activates transcription of genes whose products participate in responding to hypoxia. (Gene Ontology, GO_0097411)|
|Downloads & Tools|
2 genes participating in the hypoxia-inducible factor-1alpha signaling pathway biological process from the curated GO Biological Process Annotations dataset.