hypoxia Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description reduced oxygenation of body tissues resulting in the decreased pressure of this component of body gases; commonly due to hypoxemia (Mammalian Phenotype Ontology, MP_0005039)
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Genes

724 genes co-occuring with the biological term hypoxia in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACAN aggrecan
ACE2 angiotensin I converting enzyme 2
ACKR3 atypical chemokine receptor 3
ACO1 aconitase 1, soluble
ACO2 aconitase 2, mitochondrial
ACPP acid phosphatase, prostate
ACSS2 acyl-CoA synthetase short-chain family member 2
ADA adenosine deaminase
ADAM12 ADAM metallopeptidase domain 12
ADAM17 ADAM metallopeptidase domain 17
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADK adenosine kinase
ADM adrenomedullin
ADORA2A adenosine A2a receptor
ADORA2B adenosine A2b receptor
ADRB2 adrenoceptor beta 2, surface
AFP alpha-fetoprotein
AGGF1 angiogenic factor with G patch and FHA domains 1
AGO2 argonaute RISC catalytic component 2
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AHR aryl hydrocarbon receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALAS2 5'-aminolevulinate synthase 2
ALK anaplastic lymphoma receptor tyrosine kinase
ALKBH5 AlkB family member 5, RNA demethylase
ALOX15 arachidonate 15-lipoxygenase
ALOX15B arachidonate 15-lipoxygenase, type B
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANG angiogenin, ribonuclease, RNase A family, 5
ANGPT1 angiopoietin 1
ANGPT2 angiopoietin 2
ANGPT4 angiopoietin 4
ANGPTL4 angiopoietin-like 4
ANKRD37 ankyrin repeat domain 37
ANXA1 annexin A1
APC adenomatous polyposis coli
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APIP APAF1 interacting protein
APLN apelin
APLNR apelin receptor
APP amyloid beta (A4) precursor protein
AQP1 aquaporin 1 (Colton blood group)
AQP4 aquaporin 4
AR androgen receptor
AREG amphiregulin
ARG1 arginase 1
ARG2 arginase 2
ARNT aryl hydrocarbon receptor nuclear translocator
ARSB arylsulfatase B
ASCL1 achaete-scute family bHLH transcription factor 1
ASCL2 achaete-scute family bHLH transcription factor 2
ASPH aspartate beta-hydroxylase
ATF4 activating transcription factor 4
ATG5 autophagy related 5
ATM ATM serine/threonine kinase
ATP13A2 ATPase type 13A2
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATR ATR serine/threonine kinase
ATRIP ATR interacting protein
AURKA aurora kinase A
BAD BCL2-associated agonist of cell death
BAK1 BCL2-antagonist/killer 1
BARD1 BRCA1 associated RING domain 1
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BDKRB2 bradykinin receptor B2
BDNF brain-derived neurotrophic factor
BECN1 beclin 1, autophagy related
BHLHE40 basic helix-loop-helix family, member e40
BHLHE41 basic helix-loop-helix family, member e41
BIRC3 baculoviral IAP repeat containing 3
BIRC5 baculoviral IAP repeat containing 5
BLVRA biliverdin reductase A
BMP2 bone morphogenetic protein 2
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
BSG basigin (Ok blood group)
CA9 carbonic anhydrase IX
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CADM1 cell adhesion molecule 1
CALCRL calcitonin receptor-like
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CAPN1 calpain 1, (mu/I) large subunit
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP5 caspase 5, apoptosis-related cysteine peptidase
CASP6 caspase 6, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCL2 chemokine (C-C motif) ligand 2
CCL28 chemokine (C-C motif) ligand 28
CCL5 chemokine (C-C motif) ligand 5
CCND1 cyclin D1
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR7 chemokine (C-C motif) receptor 7
CD24 CD24 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD44 CD44 molecule (Indian blood group)
CD59 CD59 molecule, complement regulatory protein
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDC25A cell division cycle 25A
CDCA5 cell division cycle associated 5
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH5 cadherin 5, type 2 (vascular endothelium)
CDK2 cyclin-dependent kinase 2
CDK5 cyclin-dependent kinase 5
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDR2 cerebellar degeneration-related protein 2, 62kDa
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CECR1 cat eye syndrome chromosome region, candidate 1
CFH complement factor H
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHEK1 checkpoint kinase 1
CHEK2P2 checkpoint kinase 2 pseudogene 2
CHRM1 cholinergic receptor, muscarinic 1
CHRM2 cholinergic receptor, muscarinic 2
CIRBP cold inducible RNA binding protein
CLU clusterin
COL18A1 collagen, type XVIII, alpha 1
COL2A1 collagen, type II, alpha 1
CREB1 cAMP responsive element binding protein 1
CSF1 colony stimulating factor 1 (macrophage)
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CTBP1 C-terminal binding protein 1
CTF1 cardiotrophin 1
CTGF connective tissue growth factor
CTH cystathionine gamma-lyase
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNNBIP1 catenin, beta interacting protein 1
CX3CL1 chemokine (C-X3-C motif) ligand 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
CXCR6 chemokine (C-X-C motif) receptor 6
CYBB cytochrome b-245, beta polypeptide
CYGB cytoglobin
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DCK deoxycytidine kinase
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DEGS1 delta(4)-desaturase, sphingolipid 1
DEGS2 delta(4)-desaturase, sphingolipid 2
DICER1 dicer 1, ribonuclease type III
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLK1 delta-like 1 homolog (Drosophila)
DLL4 delta-like 4 (Drosophila)
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DNM2 dynamin 2
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DPP4 dipeptidyl-peptidase 4
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha)
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
DUSP1 dual specificity phosphatase 1
E2F3 E2F transcription factor 3
E2F4 E2F transcription factor 4, p107/p130-binding
EDN1 endothelin 1
EDN2 endothelin 2
EDNRB endothelin receptor type B
EEF2 eukaryotic translation elongation factor 2
EFNA3 ephrin-A3
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EGLN1 egl-9 family hypoxia-inducible factor 1
EGLN2 egl-9 family hypoxia-inducible factor 2
EGLN3 egl-9 family hypoxia-inducible factor 3
EGR1 early growth response 1
EHMT2 euchromatic histone-lysine N-methyltransferase 2
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF4E eukaryotic translation initiation factor 4E
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ELAVL1 ELAV like RNA binding protein 1
ELL elongation factor RNA polymerase II
ENG endoglin
ENO1 enolase 1, (alpha)
EP300 E1A binding protein p300
EPAS1 endothelial PAS domain protein 1
EPO erythropoietin
EPOR erythropoietin receptor
ERBB2 erb-b2 receptor tyrosine kinase 2
ERCC6 excision repair cross-complementation group 6
ERO1L ERO1-like (S. cerevisiae)
ERRFI1 ERBB receptor feedback inhibitor 1
ERVW-1 endogenous retrovirus group W, member 1
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ESRRA estrogen-related receptor alpha
ESRRB estrogen-related receptor beta
ESRRG estrogen-related receptor gamma
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
F2 coagulation factor II (thrombin)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FABP1 fatty acid binding protein 1, liver
FABP3 fatty acid binding protein 3, muscle and heart
FABP4 fatty acid binding protein 4, adipocyte
FADD Fas (TNFRSF6)-associated via death domain
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FASN fatty acid synthase
FBLN5 fibulin 5
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGF2 fibroblast growth factor 2 (basic)
FGF9 fibroblast growth factor 9
FGFR3 fibroblast growth factor receptor 3
FH fumarate hydratase
FHL2 four and a half LIM domains 2
FIGF c-fos induced growth factor (vascular endothelial growth factor D)
FLT1 fms-related tyrosine kinase 1
FLT4 fms-related tyrosine kinase 4
FLVCR1 feline leukemia virus subgroup C cellular receptor 1
FN1 fibronectin 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FOXO4 forkhead box O4
FOXP1 forkhead box P1
FOXP3 forkhead box P3
FSTL3 follistatin-like 3 (secreted glycoprotein)
FURIN furin (paired basic amino acid cleaving enzyme)
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GAST gastrin
GBE1 glucan (1,4-alpha-), branching enzyme 1
GCM1 glial cells missing homolog 1 (Drosophila)
GDF10 growth differentiation factor 10
GDF15 growth differentiation factor 15
GJA1 gap junction protein, alpha 1, 43kDa
GJB1 gap junction protein, beta 1, 32kDa
GLG1 golgi glycoprotein 1
GLIPR2 GLI pathogenesis-related 2
GLTSCR2 glioma tumor suppressor candidate region gene 2
GRB2 growth factor receptor-bound protein 2
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
GYS1 glycogen synthase 1 (muscle)
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HAMP hepcidin antimicrobial peptide
HBEGF heparin-binding EGF-like growth factor
HCRTR1 hypocretin (orexin) receptor 1
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HDAC4 histone deacetylase 4
HDAC7 histone deacetylase 7
HDC histidine decarboxylase
HES1 hes family bHLH transcription factor 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HGFAC HGF activator
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIF3A hypoxia inducible factor 3, alpha subunit
HILPDA hypoxia inducible lipid droplet-associated
HIST4H4 histone cluster 4, H4
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-G major histocompatibility complex, class I, G
HMBS hydroxymethylbilane synthase
HMGA1 high mobility group AT-hook 1
HMGB1 high mobility group box 1
HMOX1 heme oxygenase 1
HMOX2 heme oxygenase 2
HNF1B HNF1 homeobox B
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPL heterogeneous nuclear ribonucleoprotein L
HPSE heparanase
HRK harakiri, BCL2 interacting protein
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA1B heat shock 70kDa protein 1B
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA9 heat shock 70kDa protein 9 (mortalin)
HSPB1 heat shock 27kDa protein 1
HYOU1 hypoxia up-regulated 1
ICAM1 intercellular adhesion molecule 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IFNG interferon, gamma
IFT88 intraflagellar transport 88
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGFBP1 insulin-like growth factor binding protein 1
IGFBP3 insulin-like growth factor binding protein 3
IGFBP6 insulin-like growth factor binding protein 6
IGFBP7 insulin-like growth factor binding protein 7
IHH indian hedgehog
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL10 interleukin 10
IL11 interleukin 11
IL15 interleukin 15
IL17A interleukin 17A
IL18 interleukin 18
IL1B interleukin 1, beta
IL2 interleukin 2
IL20 interleukin 20
IL6 interleukin 6
ILK integrin-linked kinase
ING4 inhibitor of growth family, member 4
INHBA inhibin, beta A
IREB2 iron-responsive element binding protein 2
ISCU iron-sulfur cluster assembly enzyme
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB3BP integrin beta 3 binding protein (beta3-endonexin)
JAK1 Janus kinase 1
JAK2 Janus kinase 2
JUN jun proto-oncogene
JUND jun D proto-oncogene
KAT2B K(lysine) acetyltransferase 2B
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNK13 potassium channel, two pore domain subfamily K, member 13
KCNK2 potassium channel, two pore domain subfamily K, member 2
KCNK9 potassium channel, two pore domain subfamily K, member 9
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KDM1A lysine (K)-specific demethylase 1A
KDM3A lysine (K)-specific demethylase 3A
KDM4B lysine (K)-specific demethylase 4B
KDM4C lysine (K)-specific demethylase 4C
KDR kinase insert domain receptor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
KLF6 Kruppel-like factor 6
KLHL20 kelch-like family member 20
KMT2A lysine (K)-specific methyltransferase 2A
KRAS Kirsten rat sarcoma viral oncogene homolog
LAMA3 laminin, alpha 3
LAMP3 lysosomal-associated membrane protein 3
LCK LCK proto-oncogene, Src family tyrosine kinase
LCN2 lipocalin 2
LDHA lactate dehydrogenase A
LDHB lactate dehydrogenase B
LDLR low density lipoprotein receptor
LECT1 leukocyte cell derived chemotaxin 1
LEP leptin
LEPR leptin receptor
LGALS1 lectin, galactoside-binding, soluble, 1
LOX lysyl oxidase
LOXL2 lysyl oxidase-like 2
LPIN1 lipin 1
LRP1 low density lipoprotein receptor-related protein 1
LUC7L3 LUC7-like 3 (S. cerevisiae)
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAGED1 melanoma antigen family D1
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAX MYC associated factor X
MB myoglobin
MCAM melanoma cell adhesion molecule
MCL1 myeloid cell leukemia 1
MCM6 minichromosome maintenance complex component 6
MDK midkine (neurite growth-promoting factor 2)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MEF2C myocyte enhancer factor 2C
MET MET proto-oncogene, receptor tyrosine kinase
MGARP mitochondria-localized glutamic acid-rich protein
MICA MHC class I polypeptide-related sequence A
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR100 microRNA 100
MIR106B microRNA 106b
MIR138-1 microRNA 138-1
MIR138-2 microRNA 138-2
MIR155 microRNA 155
MIR20A microRNA 20a
MIR21 microRNA 21
MIR210 microRNA 210
MIR23B microRNA 23b
MIR27A microRNA 27a
MIR302A microRNA 302a
MIR30C1 microRNA 30c-1
MIR30C2 microRNA 30c-2
MIR361 microRNA 361
MIR424 microRNA 424
MIR494 microRNA 494
MIR497 microRNA 497
MITF microphthalmia-associated transcription factor
MLH1 mutL homolog 1
MME membrane metallo-endopeptidase
MMP1 matrix metallopeptidase 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MNS1 meiosis-specific nuclear structural 1
MPO myeloperoxidase
MSH2 mutS homolog 2
MSH3 mutS homolog 3
MST1R macrophage stimulating 1 receptor
MT-ND3 NADH dehydrogenase, subunit 3 (complex I)
MT-ND5 NADH dehydrogenase, subunit 5 (complex I)
MT2A metallothionein 2A
MTDH metadherin
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC1 mucin 1, cell surface associated
MUC17 mucin 17, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MVP major vault protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit
NANOG Nanog homeobox
NCAM1 neural cell adhesion molecule 1
NDRG1 N-myc downstream regulated 1
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NGB neuroglobin
NGF nerve growth factor (beta polypeptide)
NMBR neuromedin B receptor
NOLC1 nucleolar and coiled-body phosphoprotein 1
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NOX1 NADPH oxidase 1
NOX4 NADPH oxidase 4
NPPB natriuretic peptide B
NPPC natriuretic peptide C
NPTN-IT1 NPTN intronic transcript 1
NPTX1 neuronal pentraxin I
NR2E1 nuclear receptor subfamily 2, group E, member 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR4A3 nuclear receptor subfamily 4, group A, member 3
NRP1 neuropilin 1
NRP2 neuropilin 2
OPTC opticin
ORAI1 ORAI calcium release-activated calcium modulator 1
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PAPPA2 pappalysin 2
PARK7 parkinson protein 7
PCNA proliferating cell nuclear antigen
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDCD5 programmed cell death 5
PDE3A phosphodiesterase 3A, cGMP-inhibited
PDGFB platelet-derived growth factor beta polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDIA2 protein disulfide isomerase family A, member 2
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PER2 period circadian clock 2
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PGF placental growth factor
PHF8 PHD finger protein 8
PHLDA2 pleckstrin homology-like domain, family A, member 2
PIAS4 protein inhibitor of activated STAT, 4
PIGF phosphatidylinositol glycan anchor biosynthesis, class F
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLAC4 placenta-specific 4
PLAT plasminogen activator, tissue
PLAUR plasminogen activator, urokinase receptor
PLD2 phospholipase D2
PLIN2 perilipin 2
PLK2 polo-like kinase 2
PLK3 polo-like kinase 3
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POLI polymerase (DNA directed) iota
POSTN periostin, osteoblast specific factor
POU5F1 POU class 5 homeobox 1
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPIAL4E peptidylprolyl isomerase A (cyclophilin A)-like 4E
PPIB peptidylprolyl isomerase B (cyclophilin B)
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP1R10 protein phosphatase 1, regulatory subunit 10
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PPP1R8 protein phosphatase 1, regulatory subunit 8
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PRDX1 peroxiredoxin 1
PRDX3 peroxiredoxin 3
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
PRKCD protein kinase C, delta
PRKCE protein kinase C, epsilon
PRKCZ protein kinase C, zeta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRKG1 protein kinase, cGMP-dependent, type I
PRMT1 protein arginine methyltransferase 1
PRMT5 protein arginine methyltransferase 5
PRNP prion protein
PROM1 prominin 1
PROX1 prospero homeobox 1
PSEN1 presenilin 1
PTEN phosphatase and tensin homolog
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGES prostaglandin E synthase
PTGIS prostaglandin I2 (prostacyclin) synthase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTHLH parathyroid hormone-like hormone
PTK2 protein tyrosine kinase 2
PURA purine-rich element binding protein A
PXN paxillin
RAB22A RAB22A, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RAD51 RAD51 recombinase
RBM3 RNA binding motif (RNP1, RRM) protein 3
RDH12 retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REST RE1-silencing transcription factor
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RHOA ras homolog family member A
RHOB ras homolog family member B
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROR1 receptor tyrosine kinase-like orphan receptor 1
ROR2 receptor tyrosine kinase-like orphan receptor 2
RORA RAR-related orphan receptor A
RPA1 replication protein A1, 70kDa
RTN4 reticulon 4
RUNX2 runt-related transcription factor 2
RUNX3 runt-related transcription factor 3
S100A12 S100 calcium binding protein A12
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
S100B S100 calcium binding protein B
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCN5A sodium channel, voltage gated, type V alpha subunit
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SENP1 SUMO1/sentrin specific peptidase 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SGK1 serum/glucocorticoid regulated kinase 1
SHH sonic hedgehog
SIAH1 siah E3 ubiquitin protein ligase 1
SIAH2 siah E3 ubiquitin protein ligase 2
SIRT1 sirtuin 1
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC16A4 solute carrier family 16, member 4
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC31A1 solute carrier family 31 (copper transporter), member 1
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SLCO1B3 solute carrier organic anion transporter family, member 1B3
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SMAD7 SMAD family member 7
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SMN2 survival of motor neuron 2, centromeric
SMO smoothened, frizzled class receptor
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SNAI1 snail family zinc finger 1
SNAI2 snail family zinc finger 2
SND1 staphylococcal nuclease and tudor domain containing 1
SOAT1 sterol O-acyltransferase 1
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SOD3 superoxide dismutase 3, extracellular
SOST sclerostin
SOX9 SRY (sex determining region Y)-box 9
SP1 Sp1 transcription factor
SP3 Sp3 transcription factor
SPHK1 sphingosine kinase 1
SPHKAP SPHK1 interactor, AKAP domain containing
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SPP1 secreted phosphoprotein 1
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
SQSTM1 sequestosome 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SREBF1 sterol regulatory element binding transcription factor 1
SREBF2 sterol regulatory element binding transcription factor 2
SST somatostatin
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
STAR steroidogenic acute regulatory protein
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STC1 stanniocalcin 1
STC2 stanniocalcin 2
STIM2 stromal interaction molecule 2
STK4 serine/threonine kinase 4
STOM stomatin
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SUMO1 small ubiquitin-like modifier 1
TAGLN transgelin
TAL1 T-cell acute lymphocytic leukemia 1
TAZ tafazzin
TBXA2R thromboxane A2 receptor
TEK TEK tyrosine kinase, endothelial
TERC telomerase RNA component
TERT telomerase reverse transcriptase
TFF3 trefoil factor 3 (intestinal)
TFRC transferrin receptor
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFB3 transforming growth factor, beta 3
TGFBI transforming growth factor, beta-induced, 68kDa
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGM2 transglutaminase 2
TH tyrosine hydroxylase
THBS1 thrombospondin 1
THPO thrombopoietin
TIA1 TIA1 cytotoxic granule-associated RNA binding protein
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TIMP3 TIMP metallopeptidase inhibitor 3
TLL1 tolloid-like 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR6 toll-like receptor 6
TMPRSS4 transmembrane protease, serine 4
TMPRSS6 transmembrane protease, serine 6
TMSB4X thymosin beta 4, X-linked
TNC tenascin C
TNF tumor necrosis factor
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNNT1 troponin T type 1 (skeletal, slow)
TP53 tumor protein p53
TP53BP2 tumor protein p53 binding protein 2
TPM1 tropomyosin 1 (alpha)
TRIB3 tribbles pseudokinase 3
TRPA1 transient receptor potential cation channel, subfamily A, member 1
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TTR transthyretin
TUBB3 tubulin, beta 3 class III
TWIST1 twist family bHLH transcription factor 1
TWIST2 twist family bHLH transcription factor 2
TXN thioredoxin
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum)
TXNIP thioredoxin interacting protein
TYMP thymidine phosphorylase
UBE2I ubiquitin-conjugating enzyme E2I
UCN2 urocortin 2
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UGP2 UDP-glucose pyrophosphorylase 2
ULK1 unc-51 like autophagy activating kinase 1
UROS uroporphyrinogen III synthase
USF1 upstream transcription factor 1
USF2 upstream transcription factor 2, c-fos interacting
USP19 ubiquitin specific peptidase 19
VASH1 vasohibin 1
VASH2 vasohibin 2
VAV3 vav 3 guanine nucleotide exchange factor
VCAM1 vascular cell adhesion molecule 1
VDAC1 voltage-dependent anion channel 1
VEGFA vascular endothelial growth factor A
VEGFB vascular endothelial growth factor B
VEGFC vascular endothelial growth factor C
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VMP1 vacuole membrane protein 1
VRK2 vaccinia related kinase 2
WARS tryptophanyl-tRNA synthetase
WT1 Wilms tumor 1
XDH xanthine dehydrogenase
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YAP1 Yes-associated protein 1
YBX3 Y box binding protein 3
YTHDC1 YTH domain containing 1
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZEB1 zinc finger E-box binding homeobox 1
ZEB2 zinc finger E-box binding homeobox 2
ZFP36 ZFP36 ring finger protein
ZFP36L1 ZFP36 ring finger protein-like 1