hypoxia Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
Description reduced oxygenation of body tissues resulting in the decreased pressure of this component of body gases; commonly due to hypoxemia (Mammalian Phenotype Ontology, MP_0005039)
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Genes

74 proteins co-occuring with the biological term hypoxia in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
ACACA acetyl-CoA carboxylase alpha
AKT1 v-akt murine thymoma viral oncogene homolog 1
ARNT aryl hydrocarbon receptor nuclear translocator
ATM ATM serine/threonine kinase
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
BAD BCL2-associated agonist of cell death
CA9 carbonic anhydrase IX
CASP9 caspase 9, apoptosis-related cysteine peptidase
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHEK1 checkpoint kinase 1
CREB1 cAMP responsive element binding protein 1
CRYAB crystallin, alpha B
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
EIF4E eukaryotic translation initiation factor 4E
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ELAVL1 ELAV like RNA binding protein 1
EPAS1 endothelial PAS domain protein 1
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GCM1 glial cells missing homolog 1 (Drosophila)
GJA1 gap junction protein, alpha 1, 43kDa
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
H2AFX H2A histone family, member X
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HNRNPL heterogeneous nuclear ribonucleoprotein L
IGFBP1 insulin-like growth factor binding protein 1
IRS1 insulin receptor substrate 1
JUN jun proto-oncogene
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
LDHA lactate dehydrogenase A
MAP2K4 mitogen-activated protein kinase kinase 4
MAPK1 mitogen-activated protein kinase 1
MAPK12 mitogen-activated protein kinase 12
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MCM3 minichromosome maintenance complex component 3
MDM4 MDM4, p53 regulator
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYL12B myosin, light chain 12B, regulatory
NFE2L2 nuclear factor, erythroid 2-like 2
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NME1 NME/NM23 nucleoside diphosphate kinase 1
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PML promyelocytic leukemia
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKCQ protein kinase C, theta
PRKCZ protein kinase C, zeta
PTEN phosphatase and tensin homolog
PTK2 protein tyrosine kinase 2
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RNF7 ring finger protein 7
RPS6 ribosomal protein S6
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SIAH2 siah E3 ubiquitin protein ligase 2
SMAD3 SMAD family member 3
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TAL1 T-cell acute lymphocytic leukemia 1
TFEB transcription factor EB
TH tyrosine hydroxylase
TP53 tumor protein p53
TRIM28 tripartite motif containing 28
VCP valosin containing protein