i-kappab/nf-kappab complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex containing an inhibitory-kappaB (I-kappaB/IKB) protein and one or more copies of an NF-kappaB protein. In the resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm. (Gene Ontology, GO_0033256)
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41 proteins co-occuring with the i-kappab/nf-kappab complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.53952
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.02281
SNRPB2 small nuclear ribonucleoprotein polypeptide B 1.01883
ZBTB24 zinc finger and BTB domain containing 24 0.959268
NEK3 NIMA-related kinase 3 0.955917
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 0.898109
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 0.871346
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.863988
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 0.699543
CHRM3 cholinergic receptor, muscarinic 3 0.694709
BAG4 BCL2-associated athanogene 4 0.69427
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 0.669858
TNF tumor necrosis factor 0.61968
RAD54B RAD54 homolog B (S. cerevisiae) 0.584686
MAPK8 mitogen-activated protein kinase 8 0.573828
JUN jun proto-oncogene 0.573828
TLR5 toll-like receptor 5 0.555559
IL1B interleukin 1, beta 0.54771
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 0.538649
HOXA1 homeobox A1 0.531258
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 0.510418
MAP3K7 mitogen-activated protein kinase kinase kinase 7 0.498231
MUC2 mucin 2, oligomeric mucus/gel-forming 0.492561
REL v-rel avian reticuloendotheliosis viral oncogene homolog 0.466799
TRAF2 TNF receptor-associated factor 2 0.441312
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 0.429072
SELE selectin E 0.418468
ICAM1 intercellular adhesion molecule 1 0.408309
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.370067
TLR6 toll-like receptor 6 0.35899
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.358609
HRH1 histamine receptor H1 0.356324
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 0.332848
VCAM1 vascular cell adhesion molecule 1 0.304399
CCL2 chemokine (C-C motif) ligand 2 0.301797
IRAK1 interleukin-1 receptor-associated kinase 1 0.285507
TLR4 toll-like receptor 4 0.285138
F3 coagulation factor III (thromboplastin, tissue factor) 0.252927
TLR2 toll-like receptor 2 0.194045
AGTR1 angiotensin II receptor, type 1 0.172468
PLIN2 perilipin 2 0.165932