icosanoid biosynthetic process Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The chemical reactions and pathways resulting in the formation of icosanoids, any of a group of C20 polyunsaturated fatty acids. (Gene Ontology, GO_0046456)
External Link http://amigo.geneontology.org/amigo/term/GO:0046456
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Genes

26 genes participating in the icosanoid biosynthetic process biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2
AKR1C3 aldo-keto reductase family 1, member C3
ALOX5 arachidonate 5-lipoxygenase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
CASP1 caspase 1, apoptosis-related cysteine peptidase
CBR1 carbonyl reductase 1
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11
CYP4A22 cytochrome P450, family 4, subfamily A, polypeptide 22
LTA4H leukotriene A4 hydrolase
LTC4S leukotriene C4 synthase
MGST2 microsomal glutathione S-transferase 2
MGST3 microsomal glutathione S-transferase 3
MUSK muscle, skeletal, receptor tyrosine kinase
NAIP NLR family, apoptosis inhibitory protein
NLRC4 NLR family, CARD domain containing 4
PLA2G1B phospholipase A2, group IB (pancreas)
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLA2G5 phospholipase A2, group V
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGES2 prostaglandin E synthase 2
PTGES3 prostaglandin E synthase 3 (cytosolic)
PTGIS prostaglandin I2 (prostacyclin) synthase
PYCARD PYD and CARD domain containing
TBXAS1 thromboxane A synthase 1 (platelet)