idazoxan-3088 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the idazoxan-3088 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ADAM12 ADAM metallopeptidase domain 12
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
AMPH amphiphysin
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
BLZF1 basic leucine zipper nuclear factor 1
BTBD18 BTB (POZ) domain containing 18
C11ORF16 chromosome 11 open reading frame 16
CBX7 chromobox homolog 7
CD59 CD59 molecule, complement regulatory protein
CD84 CD84 molecule
CDC14B cell division cycle 14B
CDKN2A cyclin-dependent kinase inhibitor 2A
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CFAP70 cilia and flagella associated protein 70
CHMP6 charged multivesicular body protein 6
COBLL1 cordon-bleu WH2 repeat protein-like 1
CREM cAMP responsive element modulator
CSNK1G1 casein kinase 1, gamma 1
CYFIP2 cytoplasmic FMR1 interacting protein 2
DPEP2 dipeptidase 2
EDRF1 erythroid differentiation regulatory factor 1
EPB41 erythrocyte membrane protein band 4.1
ERN1 endoplasmic reticulum to nucleus signaling 1
FAM3A family with sequence similarity 3, member A
FAM50B family with sequence similarity 50, member B
FBXO31 F-box protein 31
FKRP fukutin related protein
GAREM GRB2 associated, regulator of MAPK1
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GOSR2 golgi SNAP receptor complex member 2
GPR35 G protein-coupled receptor 35
GSG1 germ cell associated 1
HNF1B HNF1 homeobox B
HPR haptoglobin-related protein
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFNA17 interferon, alpha 17
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
INO80B INO80 complex subunit B
ITGB4 integrin, beta 4
KCNK5 potassium channel, two pore domain subfamily K, member 5
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KDM8 lysine (K)-specific demethylase 8
KLF4 Kruppel-like factor 4 (gut)
MAOA monoamine oxidase A
MAP1A microtubule-associated protein 1A
MAPT microtubule-associated protein tau
MET MET proto-oncogene, receptor tyrosine kinase
MPZL1 myelin protein zero-like 1
MTHFSD methenyltetrahydrofolate synthetase domain containing
MUC5B mucin 5B, oligomeric mucus/gel-forming
MUC6 mucin 6, oligomeric mucus/gel-forming
NABP1 nucleic acid binding protein 1
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NLRP3 NLR family, pyrin domain containing 3
NOP16 NOP16 nucleolar protein
NQO1 NAD(P)H dehydrogenase, quinone 1
NTN3 netrin 3
ONECUT2 one cut homeobox 2
OR2H2 olfactory receptor, family 2, subfamily H, member 2
PACS1 phosphofurin acidic cluster sorting protein 1
PHC3 polyhomeotic homolog 3 (Drosophila)
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
POU2F2 POU class 2 homeobox 2
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PSG7 pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene)
PTGES prostaglandin E synthase
PVT1 Pvt1 oncogene (non-protein coding)
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RBBP9 retinoblastoma binding protein 9
RUNX1 runt-related transcription factor 1
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SLC22A17 solute carrier family 22, member 17
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC35F5 solute carrier family 35, member F5
SNPH syntaphilin
SOCS7 suppressor of cytokine signaling 7
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SRF serum response factor (c-fos serum response element-binding transcription factor)
STS steroid sulfatase (microsomal), isozyme S
SYN3 synapsin III
TAGLN3 transgelin 3
THAP9 THAP domain containing 9
THRB thyroid hormone receptor, beta
TM4SF4 transmembrane 4 L six family member 4
TNS1 tensin 1
TPMT thiopurine S-methyltransferase
TSPAN9 tetraspanin 9
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
XDH xanthine dehydrogenase
XYLB xylulokinase homolog (H. influenzae)
ZFPL1 zinc finger protein-like 1
ZNF219 zinc finger protein 219
ZNF668 zinc finger protein 668
ZNF702P zinc finger protein 702, pseudogene
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ALPK1 alpha-kinase 1
ALS2CL ALS2 C-terminal like
ANXA2P3 annexin A2 pseudogene 3
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ATG9A autophagy related 9A
BIRC3 baculoviral IAP repeat containing 3
CAMK4 calcium/calmodulin-dependent protein kinase IV
CCDC176 coiled-coil domain containing 176
CCDC9 coiled-coil domain containing 9
CD320 CD320 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CHPF chondroitin polymerizing factor
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CIDEB cell death-inducing DFFA-like effector b
CLCN6 chloride channel, voltage-sensitive 6
COL9A2 collagen, type IX, alpha 2
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CPNE1 copine I
CTAGE9 CTAGE family, member 9
DCSTAMP dendrocyte expressed seven transmembrane protein
DNM3 dynamin 3
DNMBP dynamin binding protein
DPY19L1P1 DPY19L1 pseudogene 1
DUSP8 dual specificity phosphatase 8
EDAR ectodysplasin A receptor
ELSPBP1 epididymal sperm binding protein 1
ERI3 ERI1 exoribonuclease family member 3
FAM160B2 family with sequence similarity 160, member B2
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGF9 fibroblast growth factor 9
FGGY FGGY carbohydrate kinase domain containing
FRMD1 FERM domain containing 1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GDAP1 ganglioside induced differentiation associated protein 1
GJA1 gap junction protein, alpha 1, 43kDa
GK3P glycerol kinase 3 pseudogene
GLTSCR1 glioma tumor suppressor candidate region gene 1
GTF2IRD1 GTF2I repeat domain containing 1
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLA-DMB major histocompatibility complex, class II, DM beta
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
INF2 inverted formin, FH2 and WH2 domain containing
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
JAM2 junctional adhesion molecule 2
KLF3 Kruppel-like factor 3 (basic)
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LINS lines homolog (Drosophila)
LOC730101 uncharacterized LOC730101
LRP3 low density lipoprotein receptor-related protein 3
MAST3 microtubule associated serine/threonine kinase 3
MILR1 mast cell immunoglobulin-like receptor 1
MIR22HG MIR22 host gene
MLPH melanophilin
MREG melanoregulin
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MVD mevalonate (diphospho) decarboxylase
MYO1E myosin IE
NAG18 NAG18 mRNA
NCS1 neuronal calcium sensor 1
NDE1 nudE neurodevelopment protein 1
NOL10 nucleolar protein 10
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PITX2 paired-like homeodomain 2
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLTP phospholipid transfer protein
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RNF122 ring finger protein 122
S1PR4 sphingosine-1-phosphate receptor 4
SALL2 spalt-like transcription factor 2
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SOX12 SRY (sex determining region Y)-box 12
SPHK1 sphingosine kinase 1
SPINT1 serine peptidase inhibitor, Kunitz type 1
STBD1 starch binding domain 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
THAP10 THAP domain containing 10
THEM6 thioesterase superfamily member 6
TIGD6 tigger transposable element derived 6
TMEM120B transmembrane protein 120B
TMEM140 transmembrane protein 140
TMEM212 transmembrane protein 212
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TPM3 tropomyosin 3
TRPS1 trichorhinophalangeal syndrome I
TRPV1 transient receptor potential cation channel, subfamily V, member 1
UBE2O ubiquitin-conjugating enzyme E2O
UPP1 uridine phosphorylase 1
USB1 U6 snRNA biogenesis 1
ZBTB25 zinc finger and BTB domain containing 25
ZNF492 zinc finger protein 492
ZNF671 zinc finger protein 671
ZNF813 zinc finger protein 813