| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the idazoxan-5347 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AK1 | adenylate kinase 1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ANGPTL2 | angiopoietin-like 2 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| CC2D1A | coiled-coil and C2 domain containing 1A |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CD1A | CD1a molecule |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DOCK6 | dedicator of cytokinesis 6 |
| DSTYK | dual serine/threonine and tyrosine protein kinase |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| FAM46C | family with sequence similarity 46, member C |
| FBXO31 | F-box protein 31 |
| FECH | ferrochelatase |
| FERMT2 | fermitin family member 2 |
| FGF12 | fibroblast growth factor 12 |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GPR27 | G protein-coupled receptor 27 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) |
| HSPB11 | heat shock protein family B (small), member 11 |
| ICAM1 | intercellular adhesion molecule 1 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IL1B | interleukin 1, beta |
| INO80B | INO80 complex subunit B |
| INO80D | INO80 complex subunit D |
| INSR | insulin receptor |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| ITPK1 | inositol-tetrakisphosphate 1-kinase |
| KCNK10 | potassium channel, two pore domain subfamily K, member 10 |
| KIF3C | kinesin family member 3C |
| KLF3 | Kruppel-like factor 3 (basic) |
| KLHL22 | kelch-like family member 22 |
| KLHL24 | kelch-like family member 24 |
| LBX1 | ladybird homeobox 1 |
| LIMK2 | LIM domain kinase 2 |
| LMNA | lamin A/C |
| LPIN1 | lipin 1 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MGC12488 | |
| MID1 | midline 1 |
| MITF | microphthalmia-associated transcription factor |
| MPPE1 | metallophosphoesterase 1 |
| MTERF4 | mitochondrial transcription termination factor 4 |
| NACA | nascent polypeptide-associated complex alpha subunit |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NEK1 | NIMA-related kinase 1 |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NKTR | natural killer cell triggering receptor |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 |
| ONECUT2 | one cut homeobox 2 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PDCD6 | programmed cell death 6 |
| POLH | polymerase (DNA directed), eta |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 |
| QKI | QKI, KH domain containing, RNA binding |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 |
| RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) |
| RER1 | retention in endoplasmic reticulum sorting receptor 1 |
| RGS10 | regulator of G-protein signaling 10 |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase |
| RPL23 | ribosomal protein L23 |
| S100A9 | S100 calcium binding protein A9 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SETD1A | SET domain containing 1A |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| TAOK2 | TAO kinase 2 |
| TAZ | tafazzin |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TMEM212 | transmembrane protein 212 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TUBA3C | tubulin, alpha 3c |
| TUBA4B | tubulin, alpha 4b |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked |
| WTAP | Wilms tumor 1 associated protein |
| ZBTB43 | zinc finger and BTB domain containing 43 |
| ZDHHC17 | zinc finger, DHHC-type containing 17 |
| ZNF205 | zinc finger protein 205 |
| ZNF589 | zinc finger protein 589 |
| ZNF74 | zinc finger protein 74 |
| ZNF79 | zinc finger protein 79 |
| Symbol | Name |
|---|---|
| ADRA2C | adrenoceptor alpha 2C |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ARMCX1 | armadillo repeat containing, X-linked 1 |
| BBS10 | Bardet-Biedl syndrome 10 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BCL2L2 | BCL2-like 2 |
| BRIX1 | BRX1, biogenesis of ribosomes |
| C21ORF91 | chromosome 21 open reading frame 91 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CBX7 | chromobox homolog 7 |
| CHML | choroideremia-like (Rab escort protein 2) |
| COBL | cordon-bleu WH2 repeat protein |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DCP1A | decapping mRNA 1A |
| DNA2 | DNA replication helicase/nuclease 2 |
| DUSP5 | dual specificity phosphatase 5 |
| DVL1 | dishevelled segment polarity protein 1 |
| EDC4 | enhancer of mRNA decapping 4 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FBXL14 | F-box and leucine-rich repeat protein 14 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FKBP2 | FK506 binding protein 2, 13kDa |
| FOXC1 | forkhead box C1 |
| FRAT1 | frequently rearranged in advanced T-cell lymphomas 1 |
| GAREM | GRB2 associated, regulator of MAPK1 |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GPR87 | G protein-coupled receptor 87 |
| GSTT1 | glutathione S-transferase theta 1 |
| GTPBP2 | GTP binding protein 2 |
| HGSNAT | heparan-alpha-glucosaminide N-acetyltransferase |
| HHLA3 | HERV-H LTR-associating 3 |
| HOXC11 | homeobox C11 |
| KLC2 | kinesin light chain 2 |
| KLHL26 | kelch-like family member 26 |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LMNB1 | lamin B1 |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MPI | mannose phosphate isomerase |
| MRPL35 | mitochondrial ribosomal protein L35 |
| MXRA7 | matrix-remodelling associated 7 |
| NAA38 | N(alpha)-acetyltransferase 38, NatC auxiliary subunit |
| NABP2 | nucleic acid binding protein 2 |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NDE1 | nudE neurodevelopment protein 1 |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| OCEL1 | occludin/ELL domain containing 1 |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PCID2 | PCI domain containing 2 |
| PHACTR4 | phosphatase and actin regulator 4 |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PP14571 | uncharacterized LOC100130449 |
| PPAN | peter pan homolog (Drosophila) |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PTDSS2 | phosphatidylserine synthase 2 |
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RBM42 | RNA binding motif protein 42 |
| RETSAT | retinol saturase (all-trans-retinol 13,14-reductase) |
| RNF121 | ring finger protein 121 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SIRAL2 | SIR2 antiphage like 2 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 |
| SOX3 | SRY (sex determining region Y)-box 3 |
| SYT17 | synaptotagmin XVII |
| THBS3 | thrombospondin 3 |
| THOP1 | thimet oligopeptidase 1 |
| THUMPD2 | THUMP domain containing 2 |
| TIMM10B | translocase of inner mitochondrial membrane 10 homolog B (yeast) |
| TMEM168 | transmembrane protein 168 |
| TMEM50B | transmembrane protein 50B |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TOMM22 | translocase of outer mitochondrial membrane 22 homolog (yeast) |
| TP53I3 | tumor protein p53 inducible protein 3 |
| TPCN1 | two pore segment channel 1 |
| TRIM66 | tripartite motif containing 66 |
| TSPYL2 | TSPY-like 2 |
| TUBG2 | tubulin, gamma 2 |
| USP18 | ubiquitin specific peptidase 18 |
| VGF | VGF nerve growth factor inducible |
| WDR70 | WD repeat domain 70 |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZHX2 | zinc fingers and homeoboxes 2 |
| ZNF211 | zinc finger protein 211 |
| ZNF280D | zinc finger protein 280D |
| ZNF571 | zinc finger protein 571 |
