idoxuridine-4785 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the idoxuridine-4785 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ACPP acid phosphatase, prostate
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ALOX15B arachidonate 15-lipoxygenase, type B
ALOX5 arachidonate 5-lipoxygenase
ARHGAP4 Rho GTPase activating protein 4
ARMC4 armadillo repeat containing 4
ARNTL aryl hydrocarbon receptor nuclear translocator-like
AXL AXL receptor tyrosine kinase
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BBS9 Bardet-Biedl syndrome 9
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C10ORF10 chromosome 10 open reading frame 10
CAPN9 calpain 9
CARTPT CART prepropeptide
CD209 CD209 molecule
CD47 CD47 molecule
CHML choroideremia-like (Rab escort protein 2)
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CIB2 calcium and integrin binding family member 2
CNTFR ciliary neurotrophic factor receptor
CPEB3 cytoplasmic polyadenylation element binding protein 3
CPNE7 copine VII
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYTH4 cytohesin 4
DHRS2 dehydrogenase/reductase (SDR family) member 2
DRD2 dopamine receptor D2
EFNA3 ephrin-A3
ESR1 estrogen receptor 1
FAM184A family with sequence similarity 184, member A
FILIP1L filamin A interacting protein 1-like
FLRT2 fibronectin leucine rich transmembrane protein 2
GAL galanin/GMAP prepropeptide
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
GPER1 G protein-coupled estrogen receptor 1
GPNMB glycoprotein (transmembrane) nmb
HNF4A hepatocyte nuclear factor 4, alpha
HOXC4 homeobox C4
HOXC5 homeobox C5
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IGFBP3 insulin-like growth factor binding protein 3
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IRS2 insulin receptor substrate 2
ITGA7 integrin, alpha 7
JAG1 jagged 1
KAT8 K(lysine) acetyltransferase 8
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KHK ketohexokinase (fructokinase)
KLF13 Kruppel-like factor 13
MAGEB1 melanoma antigen family B1
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MCF2L MCF.2 cell line derived transforming sequence-like
MERTK MER proto-oncogene, tyrosine kinase
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MST1L macrophage stimulating 1-like
MTA2 metastasis associated 1 family, member 2
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NIPAL2 NIPA-like domain containing 2
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
PADI3 peptidyl arginine deiminase, type III
PDE11A phosphodiesterase 11A
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PER3 period circadian clock 3
PIDD1 p53-induced death domain protein 1
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLAT plasminogen activator, tissue
POM121L2 POM121 transmembrane nucleoporin-like 2
POU5F1B POU class 5 homeobox 1B
PSEN2 presenilin 2
RAD51B RAD51 paralog B
RBBP9 retinoblastoma binding protein 9
RPS3A ribosomal protein S3A
RPS4Y1 ribosomal protein S4, Y-linked 1
RUNX1 runt-related transcription factor 1
SCAMP1 secretory carrier membrane protein 1
SENP5 SUMO1/sentrin specific peptidase 5
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMAD5 SMAD family member 5
SNCG synuclein, gamma (breast cancer-specific protein 1)
SRRT serrate, RNA effector molecule
ST5 suppression of tumorigenicity 5
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STK3 serine/threonine kinase 3
SUGP1 SURP and G patch domain containing 1
TGFBR3 transforming growth factor, beta receptor III
THPO thrombopoietin
TK2 thymidine kinase 2, mitochondrial
TLR2 toll-like receptor 2
TRPM3 transient receptor potential cation channel, subfamily M, member 3
USB1 U6 snRNA biogenesis 1
VARS valyl-tRNA synthetase
WDFY3 WD repeat and FYVE domain containing 3
ZER1 zyg-11 related, cell cycle regulator
ZNF675 zinc finger protein 675

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ATAD5 ATPase family, AAA domain containing 5
BBS10 Bardet-Biedl syndrome 10
BTD biotinidase
C5ORF45 chromosome 5 open reading frame 45
CAMTA2 calmodulin binding transcription activator 2
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC85C coiled-coil domain containing 85C
CCNL2 cyclin L2
CDK3 cyclin-dependent kinase 3
CNGB3 cyclic nucleotide gated channel beta 3
CRIP1 cysteine-rich protein 1 (intestinal)
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DTWD1 DTW domain containing 1
ERN2 endoplasmic reticulum to nucleus signaling 2
EXD3 exonuclease 3'-5' domain containing 3
FBXL2 F-box and leucine-rich repeat protein 2
FBXO22 F-box protein 22
FGD6 FYVE, RhoGEF and PH domain containing 6
FSD1 fibronectin type III and SPRY domain containing 1
GINS4 GINS complex subunit 4 (Sld5 homolog)
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPATCH3 G patch domain containing 3
HELZ helicase with zinc finger
HIST1H2AI histone cluster 1, H2ai
HIST1H2BC histone cluster 1, H2bc
HIST1H4D histone cluster 1, H4d
HYI hydroxypyruvate isomerase (putative)
IDI2-AS1 IDI2 antisense RNA 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
KCTD17 potassium channel tetramerization domain containing 17
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KRT31 keratin 31, type I
KRT8P12 keratin 8 pseudogene 12
LAMB3 laminin, beta 3
LINC00597 long intergenic non-protein coding RNA 597
LMBR1L limb development membrane protein 1-like
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MAP9 microtubule-associated protein 9
METTL2B methyltransferase like 2B
MUC3B mucin 3B, cell surface associated
MVD mevalonate (diphospho) decarboxylase
NCSTN nicastrin
NFE2L3 nuclear factor, erythroid 2-like 3
ODF2 outer dense fiber of sperm tails 2
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PADI2 peptidyl arginine deiminase, type II
PCSK7 proprotein convertase subtilisin/kexin type 7
PDZRN3 PDZ domain containing ring finger 3
PLA2G3 phospholipase A2, group III
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PRICKLE3 prickle homolog 3 (Drosophila)
PRR14L proline rich 14-like
PSKH1 protein serine kinase H1
RPH3AL rabphilin 3A-like (without C2 domains)
RPL10L ribosomal protein L10-like
S100A2 S100 calcium binding protein A2
SDC3 syndecan 3
SETD8 SET domain containing (lysine methyltransferase) 8
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPINK5 serine peptidase inhibitor, Kazal type 5
STAG3 stromal antigen 3
STEAP4 STEAP family member 4
TDRD12 tudor domain containing 12
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMC7 transmembrane channel-like 7
TMEM132A transmembrane protein 132A
TMEM180 transmembrane protein 180
TMEM184C transmembrane protein 184C
TMEM53 transmembrane protein 53
TRAIP TRAF interacting protein
TRIM25 tripartite motif containing 25
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TSPO translocator protein (18kDa)
VAV1 vav 1 guanine nucleotide exchange factor
WDR4 WD repeat domain 4
XK X-linked Kx blood group
XYLT2 xylosyltransferase II
ZBTB22 zinc finger and BTB domain containing 22
ZBTB48 zinc finger and BTB domain containing 48
ZNF205 zinc finger protein 205
ZNF211 zinc finger protein 211
ZNF250 zinc finger protein 250
ZNF35 zinc finger protein 35
ZNF446 zinc finger protein 446
ZNF586 zinc finger protein 586
ZNF652 zinc finger protein 652
ZNF665 zinc finger protein 665