ifenprodil-5044 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the ifenprodil-5044 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAN aggrecan
ADCY2 adenylate cyclase 2 (brain)
AGXT alanine-glyoxylate aminotransferase
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APOB apolipoprotein B
ARPIN actin-related protein 2/3 complex inhibitor
ASPHD1 aspartate beta-hydroxylase domain containing 1
BGN biglycan
BHMT2 betaine--homocysteine S-methyltransferase 2
C11ORF16 chromosome 11 open reading frame 16
CA9 carbonic anhydrase IX
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CARD10 caspase recruitment domain family, member 10
CASP5 caspase 5, apoptosis-related cysteine peptidase
CASS4 Cas scaffolding protein family member 4
CCL23 chemokine (C-C motif) ligand 23
CD40LG CD40 ligand
CD79A CD79a molecule, immunoglobulin-associated alpha
CDH8 cadherin 8, type 2
CDRT1 CMT1A duplicated region transcript 1
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CNGB3 cyclic nucleotide gated channel beta 3
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CRLF1 cytokine receptor-like factor 1
CSHL1 chorionic somatomammotropin hormone-like 1
CTAG2 cancer/testis antigen 2
CTSS cathepsin S
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DHRS12 dehydrogenase/reductase (SDR family) member 12
EPX eosinophil peroxidase
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
GAS1 growth arrest-specific 1
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GREM2 gremlin 2, DAN family BMP antagonist
HOXB6 homeobox B6
HRG histidine-rich glycoprotein
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
JUND jun D proto-oncogene
KALRN kalirin, RhoGEF kinase
KCTD14 potassium channel tetramerization domain containing 14
KRT12 keratin 12, type I
KYNU kynureninase
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LENEP lens epithelial protein
MAN1A2 mannosidase, alpha, class 1A, member 2
MAN2A2 mannosidase, alpha, class 2A, member 2
MMP11 matrix metallopeptidase 11
MST1 macrophage stimulating 1
MUC3A mucin 3A, cell surface associated
NMUR1 neuromedin U receptor 1
NOD2 nucleotide-binding oligomerization domain containing 2
NPPB natriuretic peptide B
NPR1 natriuretic peptide receptor 1
NRP2 neuropilin 2
OAZ3 ornithine decarboxylase antizyme 3
OR2H2 olfactory receptor, family 2, subfamily H, member 2
PARP6 poly (ADP-ribose) polymerase family, member 6
PAX2 paired box 2
PCBP3 poly(rC) binding protein 3
PCDHB17P protocadherin beta 17 pseudogene
PDE11A phosphodiesterase 11A
PHF2 PHD finger protein 2
PLAC4 placenta-specific 4
PMEL premelanosome protein
PRDM12 PR domain containing 12
RAB11B RAB11B, member RAS oncogene family
RGS16 regulator of G-protein signaling 16
RGS6 regulator of G-protein signaling 6
RHO rhodopsin
RS1 retinoschisin 1
SCAND2P SCAN domain containing 2 pseudogene
SIGLEC8 sialic acid binding Ig-like lectin 8
SLA Src-like-adaptor
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SMAD9 SMAD family member 9
STAT2 signal transducer and activator of transcription 2, 113kDa
TAS2R1 taste receptor, type 2, member 1
TBX1 T-box 1
TFDP3 transcription factor Dp family, member 3
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TRPC4 transient receptor potential cation channel, subfamily C, member 4
TRPM1 transient receptor potential cation channel, subfamily M, member 1
TTLL3 tubulin tyrosine ligase-like family member 3
TUBB1 tubulin, beta 1 class VI
VAV3 vav 3 guanine nucleotide exchange factor
VAX2 ventral anterior homeobox 2
VN1R1 vomeronasal 1 receptor 1
WNT11 wingless-type MMTV integration site family, member 11
ZMIZ2 zinc finger, MIZ-type containing 2

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ARRB2 arrestin, beta 2
ATAD5 ATPase family, AAA domain containing 5
BAK1 BCL2-antagonist/killer 1
C10ORF88 chromosome 10 open reading frame 88
C17ORF80 chromosome 17 open reading frame 80
C1ORF27 chromosome 1 open reading frame 27
C9ORF40 chromosome 9 open reading frame 40
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC88C coiled-coil domain containing 88C
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CEP131 centrosomal protein 131kDa
CHMP1A charged multivesicular body protein 1A
DAZAP1 DAZ associated protein 1
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DPY19L4 dpy-19-like 4 (C. elegans)
ECE1 endothelin converting enzyme 1
EFNA3 ephrin-A3
EPHX2 epoxide hydrolase 2, cytoplasmic
EPPK1 epiplakin 1
FBXL6 F-box and leucine-rich repeat protein 6
FBXL7 F-box and leucine-rich repeat protein 7
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FER fer (fps/fes related) tyrosine kinase
GALT galactose-1-phosphate uridylyltransferase
GAR1 GAR1 ribonucleoprotein
GAREM GRB2 associated, regulator of MAPK1
GDAP1 ganglioside induced differentiation associated protein 1
GNL2 guanine nucleotide binding protein-like 2 (nucleolar)
GPATCH2L G patch domain containing 2-like
HIST1H3A histone cluster 1, H3a
HIST1H3C histone cluster 1, H3c
HLA-J major histocompatibility complex, class I, J (pseudogene)
HYI hydroxypyruvate isomerase (putative)
IFNAR1 interferon (alpha, beta and omega) receptor 1
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KIAA0753 KIAA0753
LMCD1 LIM and cysteine-rich domains 1
LOC730101 uncharacterized LOC730101
LRRC61 leucine rich repeat containing 61
LTBP2 latent transforming growth factor beta binding protein 2
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP9 microtubule-associated protein 9
MAST3 microtubule associated serine/threonine kinase 3
MCM3AP-AS1 MCM3AP antisense RNA 1
MTERF4 mitochondrial transcription termination factor 4
MTRF1 mitochondrial translational release factor 1
NDC1 NDC1 transmembrane nucleoporin
NDP Norrie disease (pseudoglioma)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NMB neuromedin B
NME5 NME/NM23 family member 5
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLCD1 phospholipase C, delta 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
PTK7 protein tyrosine kinase 7 (inactive)
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
RBM42 RNA binding motif protein 42
RIN1 Ras and Rab interactor 1
RPGR retinitis pigmentosa GTPase regulator
SALL2 spalt-like transcription factor 2
SAMD9 sterile alpha motif domain containing 9
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SETD8 SET domain containing (lysine methyltransferase) 8
SGMS1 sphingomyelin synthase 1
SLITRK5 SLIT and NTRK-like family, member 5
SOD3 superoxide dismutase 3, extracellular
SP1 Sp1 transcription factor
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SPTBN2 spectrin, beta, non-erythrocytic 2
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
SYNC syncoilin, intermediate filament protein
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TEX40 testis expressed 40
TMEM254 transmembrane protein 254
TOR3A torsin family 3, member A
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
UGT8 UDP glycosyltransferase 8
ZC3H7A zinc finger CCCH-type containing 7A
ZCCHC10 zinc finger, CCHC domain containing 10
ZNF286A zinc finger protein 286A
ZNF350 zinc finger protein 350
ZNF37BP zinc finger protein 37B, pseudogene
ZNF711 zinc finger protein 711
ZNF816 zinc finger protein 816
ZNF83 zinc finger protein 83
ZNHIT2 zinc finger, HIT-type containing 2
ZSCAN9 zinc finger and SCAN domain containing 9
ZW10 zw10 kinetochore protein