ifenprodil-7404 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the ifenprodil-7404 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTR5 ARP5 actin-related protein 5 homolog (yeast)
ADRBK1 adrenergic, beta, receptor kinase 1
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ANKEF1 ankyrin repeat and EF-hand domain containing 1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASF1A anti-silencing function 1A histone chaperone
ASPHD1 aspartate beta-hydroxylase domain containing 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BAK1 BCL2-antagonist/killer 1
C1QTNF3 C1q and tumor necrosis factor related protein 3
CCDC68 coiled-coil domain containing 68
CDK20 cyclin-dependent kinase 20
CNGB3 cyclic nucleotide gated channel beta 3
CREBZF CREB/ATF bZIP transcription factor
DACH1 dachshund family transcription factor 1
DST dystonin
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EFNB3 ephrin-B3
EHD1 EH-domain containing 1
FGF4 fibroblast growth factor 4
FHL1 four and a half LIM domains 1
FLCN folliculin
GLRX glutaredoxin (thioltransferase)
GOSR2 golgi SNAP receptor complex member 2
GPATCH2L G patch domain containing 2-like
HBS1L HBS1-like translational GTPase
HFE hemochromatosis
HPS1 Hermansky-Pudlak syndrome 1
IFITM1 interferon induced transmembrane protein 1
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL11 interleukin 11
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
INADL InaD-like (Drosophila)
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
JMJD4 jumonji domain containing 4
KAT2A K(lysine) acetyltransferase 2A
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KCTD7 potassium channel tetramerization domain containing 7
LONP2 lon peptidase 2, peroxisomal
LPAR1 lysophosphatidic acid receptor 1
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MAN1A2 mannosidase, alpha, class 1A, member 2
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MBD1 methyl-CpG binding domain protein 1
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MMRN2 multimerin 2
MRPS11 mitochondrial ribosomal protein S11
MVD mevalonate (diphospho) decarboxylase
NCAPH2 non-SMC condensin II complex, subunit H2
NF2 neurofibromin 2 (merlin)
NOL10 nucleolar protein 10
NOS1 nitric oxide synthase 1 (neuronal)
NR4A2 nuclear receptor subfamily 4, group A, member 2
NYNRIN NYN domain and retroviral integrase containing
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PCSK6 proprotein convertase subtilisin/kexin type 6
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PLAGL1 pleiomorphic adenoma gene-like 1
PLK3 polo-like kinase 3
PLK4 polo-like kinase 4
PODNL1 podocan-like 1
PPAP2B phosphatidic acid phosphatase type 2B
PPP6R2 protein phosphatase 6, regulatory subunit 2
PRPH peripherin
PTGDS prostaglandin D2 synthase 21kDa (brain)
PVRL3 poliovirus receptor-related 3
QKI QKI, KH domain containing, RNA binding
RAB40C RAB40C, member RAS oncogene family
RABGAP1 RAB GTPase activating protein 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RNF43 ring finger protein 43
RPS4Y1 ribosomal protein S4, Y-linked 1
RUFY3 RUN and FYVE domain containing 3
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SFXN3 sideroflexin 3
SIK2 salt-inducible kinase 2
SRPK2 SRSF protein kinase 2
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STX7 syntaxin 7
TBX19 T-box 19
TDRD1 tudor domain containing 1
TESK2 testis-specific kinase 2
TM4SF5 transmembrane 4 L six family member 5
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TXNRD2 thioredoxin reductase 2
USP34 ubiquitin specific peptidase 34
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VLDLR very low density lipoprotein receptor
VPRBP Vpr (HIV-1) binding protein
YTHDC2 YTH domain containing 2
ZNF211 zinc finger protein 211
ZNF512B zinc finger protein 512B
ZNF614 zinc finger protein 614
ZSCAN2 zinc finger and SCAN domain containing 2

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ADAM15 ADAM metallopeptidase domain 15
AHDC1 AT hook, DNA binding motif, containing 1
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ANXA2P3 annexin A2 pseudogene 3
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATXN2 ataxin 2
BRPF1 bromodomain and PHD finger containing, 1
C10ORF88 chromosome 10 open reading frame 88
C11ORF68 chromosome 11 open reading frame 68
C19ORF40 chromosome 19 open reading frame 40
C4ORF29 chromosome 4 open reading frame 29
C6ORF47 chromosome 6 open reading frame 47
C7ORF43 chromosome 7 open reading frame 43
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCDC176 coiled-coil domain containing 176
CCNE1 cyclin E1
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CEP97 centrosomal protein 97kDa
CHMP7 charged multivesicular body protein 7
CHST10 carbohydrate sulfotransferase 10
CIC capicua transcriptional repressor
CINP cyclin-dependent kinase 2 interacting protein
CNPY3 canopy FGF signaling regulator 3
CORO2A coronin, actin binding protein, 2A
CPPED1 calcineurin-like phosphoesterase domain containing 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCP1A decapping mRNA 1A
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DNAL4 dynein, axonemal, light chain 4
DVL1 dishevelled segment polarity protein 1
ECHDC2 enoyl CoA hydratase domain containing 2
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
ELOVL4 ELOVL fatty acid elongase 4
EPHA4 EPH receptor A4
ERCC5 excision repair cross-complementation group 5
FAM53B family with sequence similarity 53, member B
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FZD4 frizzled class receptor 4
GAB2 GRB2-associated binding protein 2
GALK1 galactokinase 1
GJA1 gap junction protein, alpha 1, 43kDa
GTF2A1 general transcription factor IIA, 1, 19/37kDa
IGFLR1 IGF-like family receptor 1
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LRRC20 leucine rich repeat containing 20
LRRC37A2 leucine rich repeat containing 37, member A2
LRRC49 leucine rich repeat containing 49
MITF microphthalmia-associated transcription factor
MMP9 matrix metallopeptidase 9
MOCS3 molybdenum cofactor synthesis 3
NRSN2 neurensin 2
PADI2 peptidyl arginine deiminase, type II
PARP16 poly (ADP-ribose) polymerase family, member 16
PC pyruvate carboxylase
PER3 period circadian clock 3
PGP phosphoglycolate phosphatase
PIBF1 progesterone immunomodulatory binding factor 1
PIEZO1 piezo-type mechanosensitive ion channel component 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PMP22 peripheral myelin protein 22
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RCOR3 REST corepressor 3
REEP4 receptor accessory protein 4
RFTN1 raftlin, lipid raft linker 1
RNF126P1 ring finger protein 126 pseudogene 1
RNF170 ring finger protein 170
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
RRP1 ribosomal RNA processing 1
SAV1 salvador family WW domain containing protein 1
SCD5 stearoyl-CoA desaturase 5
SFT2D2 SFT2 domain containing 2
SGK1 serum/glucocorticoid regulated kinase 1
SH3BGR SH3 domain binding glutamate-rich protein
SKA1 spindle and kinetochore associated complex subunit 1
SLC12A9 solute carrier family 12, member 9
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SNIP1 Smad nuclear interacting protein 1
TBC1D17 TBC1 domain family, member 17
TMEM209 transmembrane protein 209
TRAF2 TNF receptor-associated factor 2
TSC22D4 TSC22 domain family, member 4
TUBGCP5 tubulin, gamma complex associated protein 5
TWF2 twinfilin actin binding protein 2
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
XYLT2 xylosyltransferase II
ZBTB3 zinc finger and BTB domain containing 3
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF106 zinc finger protein 106
ZNF276 zinc finger protein 276