iga glomerulonephritis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A chronic form of glomerulonephritis characterized by deposits of predominantly immunoglobulin A in the mesangial area (glomerular mesangium). Deposits of complement C3 and immunoglobulin G are also often found. Clinical features may progress from asymptomatic hematuria to end-stage kidney disease. (Experimental Factor Ontology, EFO_0004194)
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Genes

195 genes co-occuring with the disease iga glomerulonephritis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
CD79A CD79a molecule, immunoglobulin-associated alpha 3.22599
C1GALT1C1 C1GALT1-specific chaperone 1 1.90614
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 1.76139
ACE angiotensin I converting enzyme 1.64173
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 1.63993
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 1.59876
FBXL20 F-box and leucine-rich repeat protein 20 1.47901
ALB albumin 1.32148
TGFB1 transforming growth factor, beta 1 1.27781
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 1.22692
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 1.22302
FN1 fibronectin 1 1.21435
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.19316
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 1.18712
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) 1.17164
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.13924
CFP complement factor properdin 1.08873
C3 complement component 3 1.06312
CD68 CD68 molecule 1.03493
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 1.03072
C4A complement component 4A (Rodgers blood group) 0.916375
MUC20 mucin 20, cell surface associated 0.911433
PIGR polymeric immunoglobulin receptor 0.907731
SYNPO synaptopodin 0.882701
HLA-A major histocompatibility complex, class I, A 0.871234
CD4 CD4 molecule 0.86059
CFHR5 complement factor H-related 5 0.823308
TFRC transferrin receptor 0.813052
CFHR3 complement factor H-related 3 0.811411
THY1 Thy-1 cell surface antigen 0.803205
ICAM1 intercellular adhesion molecule 1 0.786394
LYZ lysozyme 0.772887
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 0.76921
IL6 interleukin 6 0.767576
CFH complement factor H 0.757378
PIGN phosphatidylinositol glycan anchor biosynthesis, class N 0.730976
B2M beta-2-microglobulin 0.727738
NAGA N-acetylgalactosaminidase, alpha- 0.721673
PCNA proliferating cell nuclear antigen 0.718846
CCL2 chemokine (C-C motif) ligand 2 0.703536
GNS glucosamine (N-acetyl)-6-sulfatase 0.693098
FCAR Fc fragment of IgA receptor 0.690293
FCAMR Fc receptor, IgA, IgM, high affinity 0.681096
PDGFB platelet-derived growth factor beta polypeptide 0.677105
MPV17 MpV17 mitochondrial inner membrane protein 0.670732
FANCB Fanconi anemia, complementation group B 0.665563
HAVCR1 hepatitis A virus cellular receptor 1 0.642221
ACTN4 actinin, alpha 4 0.626495
MPO myeloperoxidase 0.622183
CD2AP CD2-associated protein 0.617094
CD300LG CD300 molecule-like family member g 0.591337
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 0.590948
MIR148B microRNA 148b 0.587054
ZFYVE9 zinc finger, FYVE domain containing 9 0.586665
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 0.57655
CFHR1 complement factor H-related 1 0.565277
TNF tumor necrosis factor 0.555956
FDCSP follicular dendritic cell secreted protein 0.550522
PRTN3 proteinase 3 0.531154
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.528449
UBE2W ubiquitin-conjugating enzyme E2W (putative) 0.527676
AGTR1 angiotensin II receptor, type 1 0.521888
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13 0.517649
NKG7 natural killer cell granule protein 7 0.509576
MIR192 microRNA 192 0.508808
IL5RA interleukin 5 receptor, alpha 0.508424
HLA-DQB3 major histocompatibility complex, class II, DQ beta 3 0.504207
UMOD uromodulin 0.484744
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 0.483985
DDN dendrin 0.482844
PDGFD platelet derived growth factor D 0.478668
ENAH enabled homolog (Drosophila) 0.469197
SDC2 syndecan 2 0.463149
IL1RN interleukin 1 receptor antagonist 0.460883
HORMAD2 HORMA domain containing 2 0.459373
NOTO notochord homeobox 0.448817
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.448064
SPP1 secreted phosphoprotein 1 0.447311
CD19 CD19 molecule 0.440538
TLR9 toll-like receptor 9 0.433021
VWCE von Willebrand factor C and EGF domains 0.431519
ASGR2 asialoglycoprotein receptor 2 0.428516
VASN vasorin 0.424014
SELL selectin L 0.418019
INHBA inhibin, beta A 0.417644
MN1 meningioma (disrupted in balanced translocation) 1 0.416896
MBL2 mannose-binding lectin (protein C) 2, soluble 0.415024
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 0.412405
ASGR1 asialoglycoprotein receptor 1 0.412405
IL1B interleukin 1, beta 0.412031
MLEC malectin 0.405678
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) 0.396353
IGHV1-2 immunoglobulin heavy variable 1-2 0.393746
NPNT nephronectin 0.393746
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.385193
CABIN1 calcineurin binding protein 1 0.379626
AFM afamin 0.378143
NPB neuropeptide B 0.37555
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 0.366671
SPN sialophorin 0.364824
CFHR2 complement factor H-related 2 0.358551
CSN1S1 casein alpha s1 0.356341
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.355972
IL2 interleukin 2 0.353763
MTMR3 myotubularin related protein 3 0.347511
REN renin 0.347144
IL2RA interleukin 2 receptor, alpha 0.344941
TINAG tubulointerstitial nephritis antigen 0.342006
SEBOX SEBOX homeobox 0.340173
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2 0.331025
IGHMBP2 immunoglobulin mu binding protein 2 0.322637
VEGFA vascular endothelial growth factor A 0.322273
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 0.320454
USP2 ubiquitin specific peptidase 2 0.317909
TBX1 T-box 1 0.317909
CD44 CD44 molecule (Indian blood group) 0.314278
HLA-C major histocompatibility complex, class I, C 0.309204
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.307395
CRP C-reactive protein, pentraxin-related 0.303781
TBXAS1 thromboxane A synthase 1 (platelet) 0.28831
CMA1 chymase 1, mast cell 0.287952
VWF von Willebrand factor 0.285086
PLA2R1 phospholipase A2 receptor 1, 180kDa 0.284371
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.283655
PRAMEF9 PRAME family member 9 0.283297
QPRT quinolinate phosphoribosyltransferase 0.28294
AGTRAP angiotensin II receptor-associated protein 0.281868
PAGE5 P antigen family, member 5 (prostate associated) 0.279367
ADD1 adducin 1 (alpha) 0.27794
TF transferrin 0.277227
CFHR4 complement factor H-related 4 0.27687
ADM adrenomedullin 0.273308
ASCC3 activating signal cointegrator 1 complex subunit 3 0.267977
CD59 CD59 molecule, complement regulatory protein 0.264785
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 0.260184
ACTB actin, beta 0.259124
SPO11 SPO11 meiotic protein covalently bound to DSB 0.255946
IL10 interleukin 10 0.252774
AKR1C2 aldo-keto reductase family 1, member C2 0.252774
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 0.250663
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy 0.248905
OAT ornithine aminotransferase 0.24715
TFR2 transferrin receptor 2 0.243995
RARA retinoic acid receptor, alpha 0.240148
PDGFA platelet-derived growth factor alpha polypeptide 0.235964
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.234225
HPX hemopexin 0.233878
MASP2 mannan-binding lectin serine peptidase 2 0.232489
DCN decorin 0.232142
ACTG1 actin gamma 1 0.231102
CDSN corneodesmosin 0.229716
MYH9 myosin, heavy chain 9, non-muscle 0.227988
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 0.225229
BEST3 bestrophin 3 0.224884
LCN2 lipocalin 2 0.223853
CST3 cystatin C 0.219398
SOD2 superoxide dismutase 2, mitochondrial 0.212945
PXK PX domain containing serine/threonine kinase 0.212945
NES nestin 0.212271
PIAS2 protein inhibitor of activated STAT, 2 0.211934
TRPC6 transient receptor potential cation channel, subfamily C, member 6 0.210253
EDN1 endothelin 1 0.209583
APOL1 apolipoprotein L, 1 0.208579
CFB complement factor B 0.20658
CXCL8 chemokine (C-X-C motif) ligand 8 0.203933
WT1 Wilms tumor 1 0.202618
FCRL4 Fc receptor-like 4 0.199356
CD5 CD5 molecule 0.198709
SELE selectin E 0.19742
DYNLT1 dynein, light chain, Tctex-type 1 0.194865
FCN1 ficolin (collagen/fibrinogen domain containing) 1 0.192344
VCAM1 vascular cell adhesion molecule 1 0.191719
IGLL1 immunoglobulin lambda-like polypeptide 1 0.191097
ZMIZ1 zinc finger, MIZ-type containing 1 0.189859
ERC1 ELKS/RAB6-interacting/CAST family member 1 0.183248
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.182666
HMOX1 heme oxygenase 1 0.17896
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 0.177029
GLB1 galactosidase, beta 1 0.173057
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 0.172291
RND3 Rho family GTPase 3 0.171286
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.170299
ACTN1 actinin, alpha 1 0.169091
F5 coagulation factor V (proaccelerin, labile factor) 0.168854
CXCL13 chemokine (C-X-C motif) ligand 13 0.167915
TJP1 tight junction protein 1 0.167224
PPIG peptidylprolyl isomerase G (cyclophilin G) 0.165435
NOS3 nitric oxide synthase 3 (endothelial cell) 0.163111
MIR217 microRNA 217 0.162707
RCC1 regulator of chromosome condensation 1 0.162109
UBC ubiquitin C 0.160574
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.15948
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.158778
HIPK2 homeodomain interacting protein kinase 2 0.158266
TLR4 toll-like receptor 4 0.157765