igf-1 Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
Description insulin-like growth factor 1 (somatomedin C)|The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009] (NCBI Entrez Gene Database, 3479)
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Genes

52 proteins co-occuring with the biological term igf-1 in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
ADCY6 adenylate cyclase 6
AKT1 v-akt murine thymoma viral oncogene homolog 1
AR androgen receptor
ARHGAP5 Rho GTPase activating protein 5
BAD BCL2-associated agonist of cell death
BIRC5 baculoviral IAP repeat containing 5
BLVRA biliverdin reductase A
BRCA1 breast cancer 1, early onset
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CAV2 caveolin 2
CCND1 cyclin D1
CNGA1 cyclic nucleotide gated channel alpha 1
CNGB1 cyclic nucleotide gated channel beta 1
CREB1 cAMP responsive element binding protein 1
EIF4E eukaryotic translation initiation factor 4E
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
FOXG1 forkhead box G1
FOXO1 forkhead box O1
FOXO3 forkhead box O3
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
HK2 hexokinase 2
HTT huntingtin
IGF1R insulin-like growth factor 1 receptor
INSR insulin receptor
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
MAPK1 mitogen-activated protein kinase 1
MAPK15 mitogen-activated protein kinase 15
MAPK3 mitogen-activated protein kinase 3
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
METTL1 methyltransferase like 1
MITF microphthalmia-associated transcription factor
MME membrane metallo-endopeptidase
NOS3 nitric oxide synthase 3 (endothelial cell)
NUAK1 NUAK family, SNF1-like kinase, 1
PDE3A phosphodiesterase 3A, cGMP-inhibited
PDPK1 3-phosphoinositide dependent protein kinase 1
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
PRKCZ protein kinase C, zeta
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SGK1 serum/glucocorticoid regulated kinase 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STK38L serine/threonine kinase 38 like
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TBC1D4 TBC1 domain family, member 4
TP53 tumor protein p53