ikbke Gene Set

Dataset	GeneRIF Biological Term Annotations
Category	structural or functional annotations
Type	biological term
Description	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon\|IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]).[supplied by OMIM, Oct 2009] (NCBI Entrez Gene Database, 9641)
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Genes

11 genes co-occuring with the biological term ikbke in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol	Name
AKT1	v-akt murine thymoma viral oncogene homolog 1
AURKA	aurora kinase A
CXCL8	chemokine (C-X-C motif) ligand 8
FLT4	fms-related tyrosine kinase 4
FOXO3	forkhead box O3
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
MIR155	microRNA 155
PDGFRB	platelet-derived growth factor receptor, beta polypeptide
PDPK1	3-phosphoinositide dependent protein kinase 1
SRGAP2	SLIT-ROBO Rho GTPase activating protein 2
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)