il2 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Interacting selectively and non-covalently with the interleukin-2 receptor. (Gene Ontology, GO_0005134)
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Genes

218 genes co-occuring with the biological term il2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AIP aryl hydrocarbon receptor interacting protein
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALK anaplastic lymphoma receptor tyrosine kinase
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
B2M beta-2-microglobulin
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BRAF B-Raf proto-oncogene, serine/threonine kinase
BTLA B and T lymphocyte associated
CARD9 caspase recruitment domain family, member 9
CCL11 chemokine (C-C motif) ligand 11
CCL2 chemokine (C-C motif) ligand 2
CCL3 chemokine (C-C motif) ligand 3
CCL4 chemokine (C-C motif) ligand 4
CCL5 chemokine (C-C motif) ligand 5
CCND1 cyclin D1
CCND3 cyclin D3
CCNE1 cyclin E1
CCR3 chemokine (C-C motif) receptor 3
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR6 chemokine (C-C motif) receptor 6
CD247 CD247 molecule
CD27 CD27 molecule
CD274 CD274 molecule
CD28 CD28 molecule
CD4 CD4 molecule
CD40LG CD40 ligand
CD46 CD46 molecule, complement regulatory protein
CD70 CD70 molecule
CD80 CD80 molecule
CD82 CD82 molecule
CD86 CD86 molecule
CDK2 cyclin-dependent kinase 2
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CFLAR CASP8 and FADD-like apoptosis regulator
CKS1B CDC28 protein kinase regulatory subunit 1B
CREM cAMP responsive element modulator
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSW cathepsin W
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR1 chemokine (C-X-C motif) receptor 1
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR5 chemokine (C-X-C motif) receptor 5
CYP3A cytochrome P450, family 3, subfamily A
DOCK2 dedicator of cytokinesis 2
DUSP5 dual specificity phosphatase 5
EDN1 endothelin 1
ERBB2 erb-b2 receptor tyrosine kinase 2
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FASLG Fas ligand (TNF superfamily, member 6)
FGFR1 fibroblast growth factor receptor 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSL2 FOS-like antigen 2
FOXP3 forkhead box P3
FSHR follicle stimulating hormone receptor
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GLMN glomulin, FKBP associated protein
GNAS GNAS complex locus
GNLY granulysin
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GNRH2 gonadotropin-releasing hormone 2
GRAP2 GRB2-related adaptor protein 2
GSK3B glycogen synthase kinase 3 beta
HCST hematopoietic cell signal transducer
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLA-B major histocompatibility complex, class I, B
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HNRNPK heterogeneous nuclear ribonucleoprotein K
HSH2D hematopoietic SH2 domain containing
ICAM1 intercellular adhesion molecule 1
ICOS inducible T-cell co-stimulator
IDO1 indoleamine 2,3-dioxygenase 1
IFNA10 interferon, alpha 10
IFNA8 interferon, alpha 8
IFNG interferon, gamma
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKZF2 IKAROS family zinc finger 2 (Helios)
IL10 interleukin 10
IL11 interleukin 11
IL12A interleukin 12A
IL12B interleukin 12B
IL12RB2 interleukin 12 receptor, beta 2
IL13 interleukin 13
IL15 interleukin 15
IL15RA interleukin 15 receptor, alpha
IL17A interleukin 17A
IL17RA interleukin 17 receptor A
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL21 interleukin 21
IL27 interleukin 27
IL2RA interleukin 2 receptor, alpha
IL2RB interleukin 2 receptor, beta
IL2RG interleukin 2 receptor, gamma
IL3 interleukin 3
IL4 interleukin 4
IL4I1 interleukin 4 induced 1
IL5 interleukin 5
IL6 interleukin 6
IL7 interleukin 7
IL7R interleukin 7 receptor
IL9 interleukin 9
ILF2 interleukin enhancer binding factor 2
ILF3 interleukin enhancer binding factor 3, 90kDa
IRF4 interferon regulatory factor 4
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITK IL2-inducible T-cell kinase
JAK3 Janus kinase 3
JUN jun proto-oncogene
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KLF2 Kruppel-like factor 2
KLRC4 killer cell lectin-like receptor subfamily C, member 4
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KSR2 kinase suppressor of ras 2
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LEP leptin
LHCGR luteinizing hormone/choriogonadotropin receptor
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAP2K1 mitogen-activated protein kinase kinase 1
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK12 mitogen-activated protein kinase 12
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK7 mitogen-activated protein kinase 7
MDFIC MyoD family inhibitor domain containing
MIR146A microRNA 146a
MIR31 microRNA 31
MUC1 mucin 1, cell surface associated
NCAM1 neural cell adhesion molecule 1
NCR2 natural cytotoxicity triggering receptor 2
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NFE2L2 nuclear factor, erythroid 2-like 2
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NRGN neurogranin (protein kinase C substrate, RC3)
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PDCD1LG2 programmed cell death 1 ligand 2
PDCD2 programmed cell death 2
PDCD2L programmed cell death 2-like
PHB prohibitin
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PPTC7 PTC7 protein phosphatase homolog (S. cerevisiae)
PRDM1 PR domain containing 1, with ZNF domain
PRF1 perforin 1 (pore forming protein)
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKCE protein kinase C, epsilon
PRKCQ protein kinase C, theta
PRKD2 protein kinase D2
PRL prolactin
PROCR protein C receptor, endothelial
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPRC protein tyrosine phosphatase, receptor type, C
PTPRN protein tyrosine phosphatase, receptor type, N
PYGM phosphorylase, glycogen, muscle
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RNLS renalase, FAD-dependent amine oxidase
RUNX1 runt-related transcription factor 1
SGK1 serum/glucocorticoid regulated kinase 1
SH2D1A SH2 domain containing 1A
SHB Src homology 2 domain containing adaptor protein B
SIVA1 SIVA1, apoptosis-inducing factor
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLAMF1 signaling lymphocytic activation molecule family member 1
SLAMF6 SLAM family member 6
SOCS3 suppressor of cytokine signaling 3
SRSF1 serine/arginine-rich splicing factor 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
SUPT7L suppressor of Ty 7 (S. cerevisiae)-like
SYVN1 synovial apoptosis inhibitor 1, synoviolin
TBX21 T-box 21
TERT telomerase reverse transcriptase
TGFB1 transforming growth factor, beta 1
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TLR7 toll-like receptor 7
TNF tumor necrosis factor
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TOB1 transducer of ERBB2, 1
TOM1L1 target of myb1 (chicken)-like 1
TP53 tumor protein p53
TPT1 tumor protein, translationally-controlled 1
TRIM21 tripartite motif containing 21
TSC22D3 TSC22 domain family, member 3
TSHR thyroid stimulating hormone receptor
USP22 ubiquitin specific peptidase 22
VAV1 vav 1 guanine nucleotide exchange factor
WAS Wiskott-Aldrich syndrome
WASF2 WAS protein family, member 2