il2rb Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description interleukin 2 receptor, beta|The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3560)
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Genes

4 genes co-occuring with the biological term il2rb in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
IL2 interleukin 2
IL21 interleukin 21
IL2RA interleukin 2 receptor, alpha
IL2RB interleukin 2 receptor, beta