il4 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Interacting selectively and non-covalently with the interleukin-4 receptor. (Gene Ontology, GO_0005136)
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Genes

231 genes co-occuring with the biological term il4 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ADAM33 ADAM metallopeptidase domain 33
ADIPOQ adiponectin, C1Q and collagen domain containing
ADORA2A adenosine A2a receptor
ADORA2B adenosine A2b receptor
ADRB2 adrenoceptor beta 2, surface
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALOX15 arachidonate 15-lipoxygenase
ALOX15B arachidonate 15-lipoxygenase, type B
APP amyloid beta (A4) precursor protein
AR androgen receptor
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
BDKRB1 bradykinin receptor B1
BDKRB2 bradykinin receptor B2
BIRC5 baculoviral IAP repeat containing 5
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
BTLA B and T lymphocyte associated
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
C3 complement component 3
C6ORF25 chromosome 6 open reading frame 25
CALCA calcitonin-related polypeptide alpha
CARD11 caspase recruitment domain family, member 11
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCL11 chemokine (C-C motif) ligand 11
CCL13 chemokine (C-C motif) ligand 13
CCL17 chemokine (C-C motif) ligand 17
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCL2 chemokine (C-C motif) ligand 2
CCL26 chemokine (C-C motif) ligand 26
CCL5 chemokine (C-C motif) ligand 5
CCR4 chemokine (C-C motif) receptor 4
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD14 CD14 molecule
CD180 CD180 molecule
CD1A CD1a molecule
CD1D CD1d molecule
CD200 CD200 molecule
CD209 CD209 molecule
CD4 CD4 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD83 CD83 molecule
CD86 CD86 molecule
CIITA class II, major histocompatibility complex, transactivator
CLDN2 claudin 2
CLEC11A C-type lectin domain family 11, member A
CLECL1 C-type lectin-like 1
CLIP1 CAP-GLY domain containing linker protein 1
CR2 complement component (3d/Epstein Barr virus) receptor 2
CREB1 cAMP responsive element binding protein 1
CRP C-reactive protein, pentraxin-related
CRY1 cryptochrome circadian clock 1
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSF3 colony stimulating factor 3 (granulocyte)
CTGF connective tissue growth factor
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR5 chemokine (C-X-C motif) receptor 5
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYSLTR2 cysteinyl leukotriene receptor 2
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEFA5 defensin, alpha 5, Paneth cell-specific
DEFB4A defensin, beta 4A
DICER1 dicer 1, ribonuclease type III
DNASE1 deoxyribonuclease I
DUOXA2 dual oxidase maturation factor 2
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EGR1 early growth response 1
ELN elastin
FCAR Fc fragment of IgA receptor
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FLG filaggrin
FOSL2 FOS-like antigen 2
FOXP3 forkhead box P3
FUCA1 fucosidase, alpha-L- 1, tissue
FUCA2 fucosidase, alpha-L- 2, plasma
GATA3 GATA binding protein 3
GATA6 GATA binding protein 6
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GCSAM germinal center-associated, signaling and motility
GIMAP1 GTPase, IMAP family member 1
GIMAP4 GTPase, IMAP family member 4
GPR35 G protein-coupled receptor 35
HAVCR1 hepatitis A virus cellular receptor 1
HDAC1 histone deacetylase 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-B major histocompatibility complex, class I, B
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-G major histocompatibility complex, class I, G
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
ICAM1 intercellular adhesion molecule 1
ICOS inducible T-cell co-stimulator
IDO1 indoleamine 2,3-dioxygenase 1
IFNA1 interferon, alpha 1
IFNA10 interferon, alpha 10
IFNA8 interferon, alpha 8
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IFNL1 interferon, lambda 1
IFNL3 interferon, lambda 3
IGES immunoglobulin E concentration, serum
IL10 interleukin 10
IL12B interleukin 12B
IL12RB1 interleukin 12 receptor, beta 1
IL13 interleukin 13
IL13RA1 interleukin 13 receptor, alpha 1
IL13RA2 interleukin 13 receptor, alpha 2
IL15 interleukin 15
IL16 interleukin 16
IL17A interleukin 17A
IL18 interleukin 18
IL19 interleukin 19
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL21 interleukin 21
IL22 interleukin 22
IL25 interleukin 25
IL27 interleukin 27
IL2RA interleukin 2 receptor, alpha
IL2RG interleukin 2 receptor, gamma
IL3 interleukin 3
IL31 interleukin 31
IL33 interleukin 33
IL33R interleukin 33 receptor
IL3RA interleukin 3 receptor, alpha (low affinity)
IL4 interleukin 4
IL4R interleukin 4 receptor
IL5 interleukin 5
IL6 interleukin 6
IL9 interleukin 9
IRF1 interferon regulatory factor 1
IRF2 interferon regulatory factor 2
IRF4 interferon regulatory factor 4
IRF9 interferon regulatory factor 9
IRGM immunity-related GTPase family, M
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
JAK1 Janus kinase 1
JAK2 Janus kinase 2
JAK3 Janus kinase 3
JUN jun proto-oncogene
KDM6A lysine (K)-specific demethylase 6A
KITLG KIT ligand
KLK3 kallikrein-related peptidase 3
KLK7 kallikrein-related peptidase 7
KLRK1 killer cell lectin-like receptor subfamily K, member 1
LCK LCK proto-oncogene, Src family tyrosine kinase
LEF1 lymphoid enhancer-binding factor 1
LEP leptin
LEPR leptin receptor
LGALS3 lectin, galactoside-binding, soluble, 3
LIF leukemia inhibitory factor
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LTBP1 latent transforming growth factor beta binding protein 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP2K4 mitogen-activated protein kinase kinase 4
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MMP1 matrix metallopeptidase 1
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC1 mucin 1, cell surface associated
MUC2 mucin 2, oligomeric mucus/gel-forming
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NGF nerve growth factor (beta polypeptide)
PDGFB platelet-derived growth factor beta polypeptide
PIGR polymeric immunoglobulin receptor
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
POU2F1 POU class 2 homeobox 1
PPARG peroxisome proliferator-activated receptor gamma
PRF1 perforin 1 (pore forming protein)
PTAFR platelet-activating factor receptor
PTGES prostaglandin E synthase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PTPN1 protein tyrosine phosphatase, non-receptor type 1
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RHOA ras homolog family member A
RIPK2 receptor-interacting serine-threonine kinase 2
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RUNX3 runt-related transcription factor 3
S100A8 S100 calcium binding protein A8
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SEMG1 semenogelin I
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SFPQ splicing factor proline/glutamine-rich
SLC22A3 solute carrier family 22 (organic cation transporter), member 3
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SOCS1 suppressor of cytokine signaling 1
SOCS3 suppressor of cytokine signaling 3
SPIC Spi-C transcription factor (Spi-1/PU.1 related)
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT2 signal transducer and activator of transcription 2, 113kDa
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TAC1 tachykinin, precursor 1
TBX21 T-box 21
TGFB1 transforming growth factor, beta 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNC tenascin C
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8
TSLP thymic stromal lymphopoietin
VEGFA vascular endothelial growth factor A
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZFPM1 zinc finger protein, FOG family member 1