Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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194 genes differentially expressed following the iloprost-488 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ACACA | acetyl-CoA carboxylase alpha |
ACTN1 | actinin, alpha 1 |
ADAMTS7 | ADAM metallopeptidase with thrombospondin type 1 motif, 7 |
AGRN | agrin |
AP3D1 | adaptor-related protein complex 3, delta 1 subunit |
ARMC4 | armadillo repeat containing 4 |
ASIC4 | acid sensing (proton gated) ion channel family member 4 |
ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
ATP9A | ATPase, class II, type 9A |
BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
BRAP | BRCA1 associated protein |
CADM3 | cell adhesion molecule 3 |
CAV3 | caveolin 3 |
CCNT2 | cyclin T2 |
CD2AP | CD2-associated protein |
CFAP70 | cilia and flagella associated protein 70 |
CIITA | class II, major histocompatibility complex, transactivator |
COQ4 | coenzyme Q4 |
COX15 | cytochrome c oxidase assembly homolog 15 (yeast) |
DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 |
DUSP22 | dual specificity phosphatase 22 |
DYRK4 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 |
EHD1 | EH-domain containing 1 |
ENG | endoglin |
ENOX2 | ecto-NOX disulfide-thiol exchanger 2 |
ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 |
EPS8L1 | EPS8-like 1 |
FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) |
FIP1L1 | factor interacting with PAPOLA and CPSF1 |
FKBP2 | FK506 binding protein 2, 13kDa |
FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) |
GAB2 | GRB2-associated binding protein 2 |
GADD45A | growth arrest and DNA-damage-inducible, alpha |
GADD45B | growth arrest and DNA-damage-inducible, beta |
GOLM1 | golgi membrane protein 1 |
GRIK5 | glutamate receptor, ionotropic, kainate 5 |
GSK3A | glycogen synthase kinase 3 alpha |
GTPBP4 | GTP binding protein 4 |
GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
INE1 | inactivation escape 1 (non-protein coding) |
KIF1C | kinesin family member 1C |
KLHL25 | kelch-like family member 25 |
LGALS8 | lectin, galactoside-binding, soluble, 8 |
LINC00574 | long intergenic non-protein coding RNA 574 |
LMO4 | LIM domain only 4 |
LMTK2 | lemur tyrosine kinase 2 |
LPPR2 | lipid phosphate phosphatase-related protein type 2 |
LY6G6D | lymphocyte antigen 6 complex, locus G6D |
MAP3K4 | mitogen-activated protein kinase kinase kinase 4 |
MARK2 | MAP/microtubule affinity-regulating kinase 2 |
MOB3B | MOB kinase activator 3B |
MVK | mevalonate kinase |
MYH10 | myosin, heavy chain 10, non-muscle |
NADK | NAD kinase |
NFYC | nuclear transcription factor Y, gamma |
NIPBL | Nipped-B homolog (Drosophila) |
PARVA | parvin, alpha |
PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
PDXK | pyridoxal (pyridoxine, vitamin B6) kinase |
PHIP | pleckstrin homology domain interacting protein |
PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
POU5F1B | POU class 5 homeobox 1B |
PPFIA3 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 |
PSG9 | pregnancy specific beta-1-glycoprotein 9 |
PSMB10 | proteasome (prosome, macropain) subunit, beta type, 10 |
PTPRA | protein tyrosine phosphatase, receptor type, A |
PWP2 | PWP2 periodic tryptophan protein homolog (yeast) |
RBM41 | RNA binding motif protein 41 |
RHO | rhodopsin |
RING1 | ring finger protein 1 |
RITA1 | RBPJ interacting and tubulin associated 1 |
RPS2 | ribosomal protein S2 |
RUNX1 | runt-related transcription factor 1 |
SH3BP2 | SH3-domain binding protein 2 |
SIK3 | SIK family kinase 3 |
SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 |
SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
SPG20 | spastic paraplegia 20 (Troyer syndrome) |
TAF6L | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
TARBP1 | TAR (HIV-1) RNA binding protein 1 |
TBRG4 | transforming growth factor beta regulator 4 |
TCP11L1 | t-complex 11, testis-specific-like 1 |
TET3 | tet methylcytosine dioxygenase 3 |
TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 |
TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
TMPRSS5 | transmembrane protease, serine 5 |
TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
TSSC4 | tumor suppressing subtransferable candidate 4 |
TYK2 | tyrosine kinase 2 |
UBE3A | ubiquitin protein ligase E3A |
VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
WWTR1 | WW domain containing transcription regulator 1 |
ZER1 | zyg-11 related, cell cycle regulator |
ZNF580 | zinc finger protein 580 |
Symbol | Name |
---|---|
ADM2 | adrenomedullin 2 |
AMT | aminomethyltransferase |
APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) |
APCS | amyloid P component, serum |
APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
ARSF | arylsulfatase F |
ATF7 | activating transcription factor 7 |
AXIN1 | axin 1 |
C6ORF47 | chromosome 6 open reading frame 47 |
CCDC177 | coiled-coil domain containing 177 |
CD70 | CD70 molecule |
CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
CKMT2 | creatine kinase, mitochondrial 2 (sarcomeric) |
CLCA1 | chloride channel accessory 1 |
CNGB3 | cyclic nucleotide gated channel beta 3 |
COPZ2 | coatomer protein complex, subunit zeta 2 |
DAAM1 | dishevelled associated activator of morphogenesis 1 |
DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
DCUN1D2 | DCN1, defective in cullin neddylation 1, domain containing 2 |
DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
DIO3 | deiodinase, iodothyronine, type III |
DNASE1L2 | deoxyribonuclease I-like 2 |
DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
EXOC6B | exocyst complex component 6B |
FAM76A | family with sequence similarity 76, member A |
FKBP10 | FK506 binding protein 10, 65 kDa |
FOXC1 | forkhead box C1 |
FRAS1 | Fraser extracellular matrix complex subunit 1 |
GDF3 | growth differentiation factor 3 |
GLMN | glomulin, FKBP associated protein |
GLRA2 | glycine receptor, alpha 2 |
GMEB1 | glucocorticoid modulatory element binding protein 1 |
GP9 | glycoprotein IX (platelet) |
GPR15 | G protein-coupled receptor 15 |
GREB1L | growth regulation by estrogen in breast cancer-like |
GSTCD | glutathione S-transferase, C-terminal domain containing |
HIST2H2AA3 | histone cluster 2, H2aa3 |
HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
HPGDS | hematopoietic prostaglandin D synthase |
IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
IL12RB1 | interleukin 12 receptor, beta 1 |
JAM3 | junctional adhesion molecule 3 |
KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
KCNQ3 | potassium channel, voltage gated KQT-like subfamily Q, member 3 |
KIR2DL3 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 |
KLF15 | Kruppel-like factor 15 |
KLHL28 | kelch-like family member 28 |
KLRK1 | killer cell lectin-like receptor subfamily K, member 1 |
LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
LPAR3 | lysophosphatidic acid receptor 3 |
MAD2L1BP | MAD2L1 binding protein |
MADCAM1 | mucosal vascular addressin cell adhesion molecule 1 |
MAPK10 | mitogen-activated protein kinase 10 |
MEFV | Mediterranean fever |
MIP | major intrinsic protein of lens fiber |
MOGAT2 | monoacylglycerol O-acyltransferase 2 |
MT4 | metallothionein 4 |
MTERF4 | mitochondrial transcription termination factor 4 |
MUC2 | mucin 2, oligomeric mucus/gel-forming |
MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
NPFFR1 | neuropeptide FF receptor 1 |
NPY4R | neuropeptide Y receptor Y4 |
OR3A3 | olfactory receptor, family 3, subfamily A, member 3 |
OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
OVGP1 | oviductal glycoprotein 1, 120kDa |
PKD2L1 | polycystic kidney disease 2-like 1 |
PRKCZ | protein kinase C, zeta |
PRODH2 | proline dehydrogenase (oxidase) 2 |
PZP | pregnancy-zone protein |
RASL12 | RAS-like, family 12 |
RHOH | ras homolog family member H |
RLBP1 | retinaldehyde binding protein 1 |
RNF141 | ring finger protein 141 |
ROS1 | ROS proto-oncogene 1 , receptor tyrosine kinase |
SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 |
SLC13A4 | solute carrier family 13 (sodium/sulfate symporter), member 4 |
SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
SQRDL | sulfide quinone reductase-like (yeast) |
SRPK3 | SRSF protein kinase 3 |
STXBP5L | syntaxin binding protein 5-like |
SYNGR4 | synaptogyrin 4 |
SYT2 | synaptotagmin II |
T | T, brachyury homolog (mouse) |
THBS4 | thrombospondin 4 |
TMCC2 | transmembrane and coiled-coil domain family 2 |
TMEM176A | transmembrane protein 176A |
TTTY15 | testis-specific transcript, Y-linked 15 (non-protein coding) |
TUBA3C | tubulin, alpha 3c |
TULP2 | tubby like protein 2 |
USB1 | U6 snRNA biogenesis 1 |
ZNF747 | zinc finger protein 747 |