imatinib-366 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

192 genes differentially expressed following the imatinib-366 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAP1 ArfGAP with dual PH domains 1
AGER advanced glycosylation end product-specific receptor
AHDC1 AT hook, DNA binding motif, containing 1
ALAD aminolevulinate dehydratase
ANKZF1 ankyrin repeat and zinc finger domain containing 1
APOA1 apolipoprotein A-I
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ATF6 activating transcription factor 6
ATP13A2 ATPase type 13A2
B3GAT3 beta-1,3-glucuronyltransferase 3
BHLHE40 basic helix-loop-helix family, member e40
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BRCA1 breast cancer 1, early onset
BTD biotinidase
C16ORF58 chromosome 16 open reading frame 58
C5ORF45 chromosome 5 open reading frame 45
CALHM2 calcium homeostasis modulator 2
CCNL2 cyclin L2
CDC25C cell division cycle 25C
CDKN2A cyclin-dependent kinase inhibitor 2A
CLDN15 claudin 15
CNPPD1 cyclin Pas1/PHO80 domain containing 1
COBL cordon-bleu WH2 repeat protein
CPTP ceramide-1-phosphate transfer protein
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
DNAL4 dynein, axonemal, light chain 4
DSCAM Down syndrome cell adhesion molecule
DUSP13 dual specificity phosphatase 13
DUSP4 dual specificity phosphatase 4
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
EFS embryonal Fyn-associated substrate
EMC1 ER membrane protein complex subunit 1
EML2 echinoderm microtubule associated protein like 2
ENOX2 ecto-NOX disulfide-thiol exchanger 2
EVPL envoplakin
FAM114A2 family with sequence similarity 114, member A2
FAM49B family with sequence similarity 49, member B
FASTK Fas-activated serine/threonine kinase
FOSL1 FOS-like antigen 1
GAS7 growth arrest-specific 7
GFOD2 glucose-fructose oxidoreductase domain containing 2
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GOLM1 golgi membrane protein 1
GSTM4 glutathione S-transferase mu 4
GULP1 GULP, engulfment adaptor PTB domain containing 1
HLA-G major histocompatibility complex, class I, G
HMGA1 high mobility group AT-hook 1
HNF4A hepatocyte nuclear factor 4, alpha
HSPA4 heat shock 70kDa protein 4
IL19 interleukin 19
ITPKB inositol-trisphosphate 3-kinase B
KCTD2 potassium channel tetramerization domain containing 2
KIAA0040 KIAA0040
L1CAM L1 cell adhesion molecule
LHX6 LIM homeobox 6
LRRC23 leucine rich repeat containing 23
LUZP1 leucine zipper protein 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MBD3 methyl-CpG binding domain protein 3
MBOAT7 membrane bound O-acyltransferase domain containing 7
MPPE1 metallophosphoesterase 1
MT1HL1 metallothionein 1H-like 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MXD4 MAX dimerization protein 4
MYO1F myosin IF
NAGA N-acetylgalactosaminidase, alpha-
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
NRGN neurogranin (protein kinase C substrate, RC3)
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
PCNX pecanex homolog (Drosophila)
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PODNL1 podocan-like 1
PPARD peroxisome proliferator-activated receptor delta
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
RAB3D RAB3D, member RAS oncogene family
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RBMS2 RNA binding motif, single stranded interacting protein 2
RFTN1 raftlin, lipid raft linker 1
RGS17 regulator of G-protein signaling 17
SBF1 SET binding factor 1
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SIRPA signal-regulatory protein alpha
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SURF2 surfeit 2
SZRD1 SUZ RNA binding domain containing 1
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TGFA transforming growth factor, alpha
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRAFD1 TRAF-type zinc finger domain containing 1
TRAPPC12 trafficking protein particle complex 12
TSPAN32 tetraspanin 32
TSSC4 tumor suppressing subtransferable candidate 4
TXNRD2 thioredoxin reductase 2
XYLT2 xylosyltransferase II
ZFP36 ZFP36 ring finger protein
ZKSCAN1 zinc finger with KRAB and SCAN domains 1

decreased expression

Symbol Name
ACSL5 acyl-CoA synthetase long-chain family member 5
ACVRL1 activin A receptor type II-like 1
AMT aminomethyltransferase
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARMC6 armadillo repeat containing 6
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
BNC1 basonuclin 1
BNC2 basonuclin 2
C1QTNF3 C1q and tumor necrosis factor related protein 3
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CA5A carbonic anhydrase VA, mitochondrial
CA7 carbonic anhydrase VII
CAMKV CaM kinase-like vesicle-associated
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative)
CCDC176 coiled-coil domain containing 176
CD19 CD19 molecule
CD2 CD2 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CHAF1B chromatin assembly factor 1, subunit B (p60)
CSAD cysteine sulfinic acid decarboxylase
CTAGE9 CTAGE family, member 9
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
ERO1L ERO1-like (S. cerevisiae)
F11 coagulation factor XI
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FSTL4 follistatin-like 4
G0S2 G0/G1 switch 2
GAL3ST4 galactose-3-O-sulfotransferase 4
GCKR glucokinase (hexokinase 4) regulator
GDF10 growth differentiation factor 10
GNAT3 guanine nucleotide binding protein, alpha transducing 3
GUSBP3 glucuronidase, beta pseudogene 3
H2AFY2 H2A histone family, member Y2
HAPLN2 hyaluronan and proteoglycan link protein 2
HIST1H2AB histone cluster 1, H2ab
HIST1H3G histone cluster 1, H3g
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IKZF4 IKAROS family zinc finger 4 (Eos)
IL36RN interleukin 36 receptor antagonist
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KIR3DS1 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
KLHL28 kelch-like family member 28
KLHL3 kelch-like family member 3
KRT35 keratin 35, type I
KRT75 keratin 75, type II
LEFTY1 left-right determination factor 1
LGALS13 lectin, galactoside-binding, soluble, 13
LINC00574 long intergenic non-protein coding RNA 574
LOC100286895 cell division cycle 27 homolog pseudogene
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LUZP2 leucine zipper protein 2
MAGEC3 melanoma antigen family C3
MOB3B MOB kinase activator 3B
MRPL41 mitochondrial ribosomal protein L41
MYL2 myosin, light chain 2, regulatory, cardiac, slow
MYOZ3 myozenin 3
NMRK2 nicotinamide riboside kinase 2
NPR3 natriuretic peptide receptor 3
OR12D3 olfactory receptor, family 12, subfamily D, member 3
PCDH11X protocadherin 11 X-linked
PCTP phosphatidylcholine transfer protein
PDZD7 PDZ domain containing 7
PF4 platelet factor 4
PHC1 polyhomeotic homolog 1 (Drosophila)
PLVAP plasmalemma vesicle associated protein
POPDC2 popeye domain containing 2
PPP1R17 protein phosphatase 1, regulatory subunit 17
PROL1 proline rich, lacrimal 1
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RASL10A RAS-like, family 10, member A
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
SDK2 sidekick cell adhesion molecule 2
SIGLEC5 sialic acid binding Ig-like lectin 5
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1
SLC39A2 solute carrier family 39 (zinc transporter), member 2
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLURP1 secreted LY6/PLAUR domain containing 1
SOX21 SRY (sex determining region Y)-box 21
TH tyrosine hydroxylase
THBS2 thrombospondin 2
TIMP2 TIMP metallopeptidase inhibitor 2
TMEM209 transmembrane protein 209
TSPAN7 tetraspanin 7
VSIG4 V-set and immunoglobulin domain containing 4
WNT2 wingless-type MMTV integration site family member 2
ZIC4 Zic family member 4
ZNRF4 zinc and ring finger 4