imidurea-5481 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

197 genes differentially expressed following the imidurea-5481 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ACAN aggrecan
ADAM8 ADAM metallopeptidase domain 8
ADCK4 aarF domain containing kinase 4
ADGRL1 adhesion G protein-coupled receptor L1
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARR3 arrestin 3, retinal (X-arrestin)
C19ORF73 chromosome 19 open reading frame 73
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCRL2 chemokine (C-C motif) receptor-like 2
CD58 CD58 molecule
CDK13 cyclin-dependent kinase 13
CFAP45 cilia and flagella associated protein 45
CPNE7 copine VII
CRHR1 corticotropin releasing hormone receptor 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DLK2 delta-like 2 homolog (Drosophila)
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DOCK1 dedicator of cytokinesis 1
DOK4 docking protein 4
DST dystonin
EGFL7 EGF-like-domain, multiple 7
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
F13A1 coagulation factor XIII, A1 polypeptide
FADS2 fatty acid desaturase 2
FAM134B family with sequence similarity 134, member B
FLJ42627 uncharacterized LOC645644
FOXF1 forkhead box F1
FOXN3 forkhead box N3
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GH1 growth hormone 1
GJA9 gap junction protein, alpha 9, 59kDa
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPR21 G protein-coupled receptor 21
HAL histidine ammonia-lyase
HMGN5 high mobility group nucleosome binding domain 5
ICA1 islet cell autoantigen 1, 69kDa
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IFT38 intraflagellar transport 38
IPO8 importin 8
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KIF21B kinesin family member 21B
KIF25 kinesin family member 25
LAMC2 laminin, gamma 2
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LINC00341 long intergenic non-protein coding RNA 341
LMOD1 leiomodin 1 (smooth muscle)
LONRF3 LON peptidase N-terminal domain and ring finger 3
LPIN2 lipin 2
LRRC61 leucine rich repeat containing 61
LUZP1 leucine zipper protein 1
MARK4 MAP/microtubule affinity-regulating kinase 4
MCF2L MCF.2 cell line derived transforming sequence-like
MEG3 maternally expressed 3 (non-protein coding)
MFGE8 milk fat globule-EGF factor 8 protein
MOBP myelin-associated oligodendrocyte basic protein
MON2 MON2 homolog (S. cerevisiae)
MSR1 macrophage scavenger receptor 1
MTSS1 metastasis suppressor 1
MVK mevalonate kinase
MX2 MX dynamin-like GTPase 2
NBEAL2 neurobeachin-like 2
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NELL2 NEL-like 2 (chicken)
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
PAX4 paired box 4
PEG10 paternally expressed 10
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRSS21 protease, serine, 21 (testisin)
PSEN2 presenilin 2
PTCRA pre T-cell antigen receptor alpha
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RARA retinoic acid receptor, alpha
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RPH3A rabphilin 3A
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SATB2 SATB homeobox 2
SCN10A sodium channel, voltage gated, type X alpha subunit
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SIRPB1 signal-regulatory protein beta 1
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SNTG1 syntrophin, gamma 1
SOGA1 suppressor of glucose, autophagy associated 1
STX5 syntaxin 5
TAT tyrosine aminotransferase
TBX3 T-box 3
TH tyrosine hydroxylase
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TPMT thiopurine S-methyltransferase
TSPAN1 tetraspanin 1
VAV2 vav 2 guanine nucleotide exchange factor
ZBTB7A zinc finger and BTB domain containing 7A
ZDHHC8P1 zinc finger, DHHC-type containing 8 pseudogene 1
ZMYND8 zinc finger, MYND-type containing 8
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ADAP2 ArfGAP with dual PH domains 2
AFF4 AF4/FMR2 family, member 4
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASB9 ankyrin repeat and SOCS box containing 9
ATP13A2 ATPase type 13A2
BBC3 BCL2 binding component 3
C22ORF29 chromosome 22 open reading frame 29
CAPRIN2 caprin family member 2
CBX7 chromobox homolog 7
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC85C coiled-coil domain containing 85C
CCNL2 cyclin L2
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
DCAF16 DDB1 and CUL4 associated factor 16
DGKE diacylglycerol kinase, epsilon 64kDa
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DNM1 dynamin 1
DSCAM Down syndrome cell adhesion molecule
ELP3 elongator acetyltransferase complex subunit 3
EPPK1 epiplakin 1
ERN2 endoplasmic reticulum to nucleus signaling 2
EYA2 EYA transcriptional coactivator and phosphatase 2
FAM127B family with sequence similarity 127, member B
FBXO31 F-box protein 31
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GADD45A growth arrest and DNA-damage-inducible, alpha
GALT galactose-1-phosphate uridylyltransferase
HDAC4 histone deacetylase 4
HMG20A high mobility group 20A
HMOX1 heme oxygenase 1
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IKZF5 IKAROS family zinc finger 5 (Pegasus)
INO80D INO80 complex subunit D
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITPKB inositol-trisphosphate 3-kinase B
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LMBR1L limb development membrane protein 1-like
LMNB1 lamin B1
LOC100286895 cell division cycle 27 homolog pseudogene
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MB myoglobin
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCOLN3 mucolipin 3
METTL2B methyltransferase like 2B
MORC3 MORC family CW-type zinc finger 3
MYL5 myosin, light chain 5, regulatory
MYO1D myosin ID
NECAB3 N-terminal EF-hand calcium binding protein 3
NIPAL2 NIPA-like domain containing 2
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OGFRL1 opioid growth factor receptor-like 1
PCSK7 proprotein convertase subtilisin/kexin type 7
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLA2G3 phospholipase A2, group III
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
PROCR protein C receptor, endothelial
RAB4B RAB4B, member RAS oncogene family
RETSAT retinol saturase (all-trans-retinol 13,14-reductase)
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RPL13P5 ribosomal protein L13 pseudogene 5
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SCN1B sodium channel, voltage gated, type I beta subunit
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC46A3 solute carrier family 46, member 3
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SNORA21 small nucleolar RNA, H/ACA box 21
SOWAHC sosondowah ankyrin repeat domain family member C
ST20 suppressor of tumorigenicity 20
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STK25 serine/threonine kinase 25
STRN4 striatin, calmodulin binding protein 4
TCTA T-cell leukemia translocation altered
TM6SF1 transmembrane 6 superfamily member 1
TMEM183A transmembrane protein 183A
TMEM53 transmembrane protein 53
TRABD TraB domain containing
TRAPPC11 trafficking protein particle complex 11
TWF2 twinfilin actin binding protein 2
URGCP upregulator of cell proliferation
USB1 U6 snRNA biogenesis 1
USP27X ubiquitin specific peptidase 27, X-linked
WDR7 WD repeat domain 7
XAB2 XPA binding protein 2
ZNF212 zinc finger protein 212
ZNF276 zinc finger protein 276
ZNF675 zinc finger protein 675
ZNF747 zinc finger protein 747
ZNF816 zinc finger protein 816
ZNHIT2 zinc finger, HIT-type containing 2