| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the imipenem-1724 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GNT | alpha-1,4-N-acetylglucosaminyltransferase |
| AAMDC | adipogenesis associated, Mth938 domain containing |
| ABCF2 | ATP-binding cassette, sub-family F (GCN20), member 2 |
| ACAN | aggrecan |
| ACOT7 | acyl-CoA thioesterase 7 |
| AGTPBP1 | ATP/GTP binding protein 1 |
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AMBRA1 | autophagy/beclin-1 regulator 1 |
| AP3D1 | adaptor-related protein complex 3, delta 1 subunit |
| ARHGAP4 | Rho GTPase activating protein 4 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 |
| ARL4D | ADP-ribosylation factor-like 4D |
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like |
| ATG4B | autophagy related 4B, cysteine peptidase |
| BPHL | biphenyl hydrolase-like (serine hydrolase) |
| C2CD2L | C2CD2-like |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CAPN10 | calpain 10 |
| CCDC64 | coiled-coil domain containing 64 |
| CDC42 | cell division cycle 42 |
| CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLTCL1 | clathrin, heavy chain-like 1 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| DND1 | DND microRNA-mediated repression inhibitor 1 |
| EFHD1 | EF-hand domain family, member D1 |
| EPHB2 | EPH receptor B2 |
| FAM3A | family with sequence similarity 3, member A |
| FAM57A | family with sequence similarity 57, member A |
| FBXO42 | F-box protein 42 |
| GCKR | glucokinase (hexokinase 4) regulator |
| GJD2 | gap junction protein, delta 2, 36kDa |
| GNB5 | guanine nucleotide binding protein (G protein), beta 5 |
| GPR107 | G protein-coupled receptor 107 |
| GSE1 | Gse1 coiled-coil protein |
| HIST1H4J | histone cluster 1, H4j |
| HK2 | hexokinase 2 |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
| IMPAD1 | inositol monophosphatase domain containing 1 |
| ITGB5 | integrin, beta 5 |
| KLHL22 | kelch-like family member 22 |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| LAD1 | ladinin 1 |
| LSP1 | lymphocyte-specific protein 1 |
| MAN1B1 | mannosidase, alpha, class 1B, member 1 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MSH3 | mutS homolog 3 |
| MST1 | macrophage stimulating 1 |
| MYL10 | myosin, light chain 10, regulatory |
| NAAA | N-acylethanolamine acid amidase |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NDRG2 | NDRG family member 2 |
| NOC4L | nucleolar complex associated 4 homolog (S. cerevisiae) |
| NPDC1 | neural proliferation, differentiation and control, 1 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) |
| PARD3 | par-3 family cell polarity regulator |
| PDCD11 | programmed cell death 11 |
| PIGV | phosphatidylinositol glycan anchor biosynthesis, class V |
| PKNOX1 | PBX/knotted 1 homeobox 1 |
| PLCB2 | phospholipase C, beta 2 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PLLP | plasmolipin |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 |
| RHOT2 | ras homolog family member T2 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| SEC31B | SEC31 homolog B (S. cerevisiae) |
| SENP3 | SUMO1/sentrin/SMT3 specific peptidase 3 |
| SF3A2 | splicing factor 3a, subunit 2, 66kDa |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SIDT2 | SID1 transmembrane family, member 2 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 |
| SLC6A3 | solute carrier family 6 (neurotransmitter transporter), member 3 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SMAD3 | SMAD family member 3 |
| SMG5 | SMG5 nonsense mediated mRNA decay factor |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| STX17 | syntaxin 17 |
| SZT2 | seizure threshold 2 homolog (mouse) |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 |
| TCF3 | transcription factor 3 |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) |
| TGFB3 | transforming growth factor, beta 3 |
| TNK1 | tyrosine kinase, non-receptor, 1 |
| TNXB | tenascin XB |
| TRA | T cell receptor alpha locus |
| TRAPPC12 | trafficking protein particle complex 12 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| UBE2O | ubiquitin-conjugating enzyme E2O |
| USF2 | upstream transcription factor 2, c-fos interacting |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| Symbol | Name |
|---|---|
| ACO1 | aconitase 1, soluble |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ADCY7 | adenylate cyclase 7 |
| ADRB2 | adrenoceptor beta 2, surface |
| ADSS | adenylosuccinate synthase |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit |
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 |
| BCOR | BCL6 corepressor |
| BTK | Bruton agammaglobulinemia tyrosine kinase |
| C11ORF73 | chromosome 11 open reading frame 73 |
| C12ORF49 | chromosome 12 open reading frame 49 |
| C1ORF27 | chromosome 1 open reading frame 27 |
| CDC73 | cell division cycle 73 |
| CEP170B | centrosomal protein 170B |
| CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 |
| CHCHD7 | coiled-coil-helix-coiled-coil-helix domain containing 7 |
| CHMP1A | charged multivesicular body protein 1A |
| CHST4 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLSTN1 | calsyntenin 1 |
| CS | citrate synthase |
| CTSL | cathepsin L |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
| DYNC1LI1 | dynein, cytoplasmic 1, light intermediate chain 1 |
| ECM1 | extracellular matrix protein 1 |
| ECT2 | epithelial cell transforming 2 |
| EDAR | ectodysplasin A receptor |
| EHD4 | EH-domain containing 4 |
| EIF4ENIF1 | eukaryotic translation initiation factor 4E nuclear import factor 1 |
| ELP5 | elongator acetyltransferase complex subunit 5 |
| FBXO5 | F-box protein 5 |
| FOXM1 | forkhead box M1 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| FZD2 | frizzled class receptor 2 |
| GATAD2A | GATA zinc finger domain containing 2A |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GCA | grancalcin, EF-hand calcium binding protein |
| GPR183 | G protein-coupled receptor 183 |
| GRM6 | glutamate receptor, metabotropic 6 |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HAUS3 | HAUS augmin-like complex, subunit 3 |
| HAUS7 | HAUS augmin-like complex, subunit 7 |
| HIST1H2AC | histone cluster 1, H2ac |
| ISG15 | ISG15 ubiquitin-like modifier |
| KAT2B | K(lysine) acetyltransferase 2B |
| KCTD5 | potassium channel tetramerization domain containing 5 |
| KDM5C | lysine (K)-specific demethylase 5C |
| LMAN2L | lectin, mannose-binding 2-like |
| MEST | mesoderm specific transcript |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 |
| MT1HL1 | metallothionein 1H-like 1 |
| MTF1 | metal-regulatory transcription factor 1 |
| MTG1 | mitochondrial ribosome-associated GTPase 1 |
| MTHFS | 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit |
| NACAP1 | nascent-polypeptide-associated complex alpha polypeptide pseudogene 1 |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein |
| NOC2L | nucleolar complex associated 2 homolog (S. cerevisiae) |
| NRBF2 | nuclear receptor binding factor 2 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 |
| OPHN1 | oligophrenin 1 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| ORC2 | origin recognition complex, subunit 2 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| PAQR4 | progestin and adipoQ receptor family member IV |
| PARG | poly (ADP-ribose) glycohydrolase |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PNKP | polynucleotide kinase 3'-phosphatase |
| PODNL1 | podocan-like 1 |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PRPF3 | pre-mRNA processing factor 3 |
| PRPF39 | pre-mRNA processing factor 39 |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| RAB1B | RAB1B, member RAS oncogene family |
| RCBTB1 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RPS14P3 | ribosomal protein S14 pseudogene 3 |
| RWDD3 | RWD domain containing 3 |
| SH2B3 | SH2B adaptor protein 3 |
| SLC50A1 | solute carrier family 50 (sugar efflux transporter), member 1 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 |
| SUSD6 | sushi domain containing 6 |
| TMEM115 | transmembrane protein 115 |
| TMEM14A | transmembrane protein 14A |
| TMEM156 | transmembrane protein 156 |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| TSPAN31 | tetraspanin 31 |
| TSPAN32 | tetraspanin 32 |
| TVP23B | trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) |
| UGGT1 | UDP-glucose glycoprotein glucosyltransferase 1 |
| USP39 | ubiquitin specific peptidase 39 |
| VASP | vasodilator-stimulated phosphoprotein |
| WDR70 | WD repeat domain 70 |
| WEE1 | WEE1 G2 checkpoint kinase |
| WFDC2 | WAP four-disulfide core domain 2 |
| XKR8 | XK, Kell blood group complex subunit-related family, member 8 |
