| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the imipenem-2873 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAMDC | adipogenesis associated, Mth938 domain containing |
| ADAMTSL3 | ADAMTS-like 3 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARID1A | AT rich interactive domain 1A (SWI-like) |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| C17ORF59 | chromosome 17 open reading frame 59 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase |
| CCDC7 | coiled-coil domain containing 7 |
| CD22 | CD22 molecule |
| CD58 | CD58 molecule |
| CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 |
| CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 |
| CHRM2 | cholinergic receptor, muscarinic 2 |
| CRYM | crystallin, mu |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) |
| CTNS | cystinosin, lysosomal cystine transporter |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DLGAP2 | discs, large (Drosophila) homolog-associated protein 2 |
| DNAI2 | dynein, axonemal, intermediate chain 2 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A |
| ELMO1 | engulfment and cell motility 1 |
| EMID1 | EMI domain containing 1 |
| EPS15L1 | epidermal growth factor receptor pathway substrate 15-like 1 |
| ERP44 | endoplasmic reticulum protein 44 |
| EVI5 | ecotropic viral integration site 5 |
| EXOSC1 | exosome component 1 |
| FBLN1 | fibulin 1 |
| FCN2 | ficolin (collagen/fibrinogen domain containing lectin) 2 |
| FGF20 | fibroblast growth factor 20 |
| FGFR1OP | FGFR1 oncogene partner |
| FGFR4 | fibroblast growth factor receptor 4 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| FXYD5 | FXYD domain containing ion transport regulator 5 |
| GPC3 | glypican 3 |
| GPR39 | G protein-coupled receptor 39 |
| GPR75 | G protein-coupled receptor 75 |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HOXA10 | homeobox A10 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 |
| ISL1 | ISL LIM homeobox 1 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| ITM2C | integral membrane protein 2C |
| JAG1 | jagged 1 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KLHL25 | kelch-like family member 25 |
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 |
| MEF2D | myocyte enhancer factor 2D |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MRPL41 | mitochondrial ribosomal protein L41 |
| N4BP3 | NEDD4 binding protein 3 |
| NEFL | neurofilament, light polypeptide |
| NELL2 | NEL-like 2 (chicken) |
| NNAT | neuronatin |
| NPY6R | neuropeptide Y receptor Y6 (pseudogene) |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| PCDH17 | protocadherin 17 |
| PDLIM4 | PDZ and LIM domain 4 |
| PHF20L1 | PHD finger protein 20-like 1 |
| PIDD1 | p53-induced death domain protein 1 |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PON3 | paraoxonase 3 |
| POU4F1 | POU class 4 homeobox 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 |
| RASA3 | RAS p21 protein activator 3 |
| RUNX1 | runt-related transcription factor 1 |
| SCN4A | sodium channel, voltage gated, type IV alpha subunit |
| SIGLEC6 | sialic acid binding Ig-like lectin 6 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SLN | sarcolipin |
| SOAT2 | sterol O-acyltransferase 2 |
| SOHLH2 | spermatogenesis and oogenesis specific basic helix-loop-helix 2 |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 |
| SPTB | spectrin, beta, erythrocytic |
| SRCAP | Snf2-related CREBBP activator protein |
| STIM1 | stromal interaction molecule 1 |
| TDRD12 | tudor domain containing 12 |
| TEF | thyrotrophic embryonic factor |
| TERT | telomerase reverse transcriptase |
| TLDC1 | TBC/LysM-associated domain containing 1 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TMEM121 | transmembrane protein 121 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TONSL | tonsoku-like, DNA repair protein |
| VNN2 | vanin 2 |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| ZFP64 | ZFP64 zinc finger protein |
| ZFPM2 | zinc finger protein, FOG family member 2 |
| ZMAT4 | zinc finger, matrin-type 4 |
| ZNF552 | zinc finger protein 552 |
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ANKRD40 | ankyrin repeat domain 40 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| AXIN1 | axin 1 |
| BCKDHA | branched chain keto acid dehydrogenase E1, alpha polypeptide |
| C11ORF30 | chromosome 11 open reading frame 30 |
| CBLL1 | Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase |
| CBR1 | carbonyl reductase 1 |
| CCDC85C | coiled-coil domain containing 85C |
| CDK3 | cyclin-dependent kinase 3 |
| CDK5 | cyclin-dependent kinase 5 |
| CIC | capicua transcriptional repressor |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CNPY3 | canopy FGF signaling regulator 3 |
| CXORF56 | chromosome X open reading frame 56 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) |
| DNALI1 | dynein, axonemal, light intermediate chain 1 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| FBXO31 | F-box protein 31 |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FFAR2 | free fatty acid receptor 2 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GCA | grancalcin, EF-hand calcium binding protein |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H3B | histone cluster 1, H3b |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
| IFT140 | intraflagellar transport 140 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| KCNK15 | potassium channel, two pore domain subfamily K, member 15 |
| KIF3A | kinesin family member 3A |
| LARS | leucyl-tRNA synthetase |
| LMNB1 | lamin B1 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LRRC37A2 | leucine rich repeat containing 37, member A2 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MBTD1 | mbt domain containing 1 |
| MCOLN1 | mucolipin 1 |
| METTL16 | methyltransferase like 16 |
| MGC12488 | |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive |
| NLRX1 | NLR family member X1 |
| NMU | neuromedin U |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NPY1R | neuropeptide Y receptor Y1 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| OSMR | oncostatin M receptor |
| PCDHB13 | protocadherin beta 13 |
| PHF14 | PHD finger protein 14 |
| PLA2G10 | phospholipase A2, group X |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PNPLA6 | patatin-like phospholipase domain containing 6 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRR4 | proline rich 4 (lacrimal) |
| RBL1 | retinoblastoma-like 1 |
| RBM42 | RNA binding motif protein 42 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| RWDD3 | RWD domain containing 3 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
| SPRYD7 | SPRY domain containing 7 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) |
| STAG3 | stromal antigen 3 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TAOK1 | TAO kinase 1 |
| TBP | TATA box binding protein |
| THOP1 | thimet oligopeptidase 1 |
| TLR2 | toll-like receptor 2 |
| TPCN1 | two pore segment channel 1 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
| VWA1 | von Willebrand factor A domain containing 1 |
| WDR33 | WD repeat domain 33 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| XYLT2 | xylosyltransferase II |
| YIPF3 | Yip1 domain family, member 3 |
| YY2 | YY2 transcription factor |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF273 | zinc finger protein 273 |
| ZNF324 | zinc finger protein 324 |
| ZNF329 | zinc finger protein 329 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF480 | zinc finger protein 480 |
| ZNF573 | zinc finger protein 573 |
| ZNF639 | zinc finger protein 639 |
