| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the imipenem-5997 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADRB1 | adrenoceptor beta 1 |
| AIM2 | absent in melanoma 2 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| ATG10 | autophagy related 10 |
| ATP9B | ATPase, class II, type 9B |
| ATXN2L | ataxin 2-like |
| BCL2 | B-cell CLL/lymphoma 2 |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C3ORF18 | chromosome 3 open reading frame 18 |
| C8A | complement component 8, alpha polypeptide |
| CCDC64 | coiled-coil domain containing 64 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CDK14 | cyclin-dependent kinase 14 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CPQ | carboxypeptidase Q |
| CYBB | cytochrome b-245, beta polypeptide |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| CYP39A1 | cytochrome P450, family 39, subfamily A, polypeptide 1 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| DGCR14 | DiGeorge syndrome critical region gene 14 |
| DLX4 | distal-less homeobox 4 |
| DOCK5 | dedicator of cytokinesis 5 |
| DRD2 | dopamine receptor D2 |
| FBN1 | fibrillin 1 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FGF18 | fibroblast growth factor 18 |
| FHL1 | four and a half LIM domains 1 |
| GAS7 | growth arrest-specific 7 |
| GRM7 | glutamate receptor, metabotropic 7 |
| HCN2 | hyperpolarization activated cyclic nucleotide gated potassium channel 2 |
| HIC2 | hypermethylated in cancer 2 |
| HIST1H4E | histone cluster 1, H4e |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFT27 | intraflagellar transport 27 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IL4R | interleukin 4 receptor |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KLHL11 | kelch-like family member 11 |
| KRT17 | keratin 17, type I |
| LGALS14 | lectin, galactoside-binding, soluble, 14 |
| MAP4 | microtubule-associated protein 4 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MRE11A | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) |
| NCOA2 | nuclear receptor coactivator 2 |
| NID1 | nidogen 1 |
| NIPAL3 | NIPA-like domain containing 3 |
| NOP16 | NOP16 nucleolar protein |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| NXF2 | nuclear RNA export factor 2 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| PCDHB13 | protocadherin beta 13 |
| PCDHGA10 | protocadherin gamma subfamily A, 10 |
| PDE10A | phosphodiesterase 10A |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PIGC | phosphatidylinositol glycan anchor biosynthesis, class C |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PLK3 | polo-like kinase 3 |
| PRND | prion protein 2 (dublet) |
| PRR5 | proline rich 5 (renal) |
| PTCRA | pre T-cell antigen receptor alpha |
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) |
| RAB6B | RAB6B, member RAS oncogene family |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RFTN1 | raftlin, lipid raft linker 1 |
| RGS5 | regulator of G-protein signaling 5 |
| RNF122 | ring finger protein 122 |
| S100A7 | S100 calcium binding protein A7 |
| S100A8 | S100 calcium binding protein A8 |
| S100A9 | S100 calcium binding protein A9 |
| SCARA3 | scavenger receptor class A, member 3 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SIRT5 | sirtuin 5 |
| SLC17A2 | solute carrier family 17, member 2 |
| SOX18 | SRY (sex determining region Y)-box 18 |
| SYNDIG1 | synapse differentiation inducing 1 |
| SYP | synaptophysin |
| SYT5 | synaptotagmin V |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TNS1 | tensin 1 |
| TRIM10 | tripartite motif containing 10 |
| TRIM3 | tripartite motif containing 3 |
| TSC22D2 | TSC22 domain family, member 2 |
| TTC38 | tetratricopeptide repeat domain 38 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF419 | zinc finger protein 419 |
| Symbol | Name |
|---|---|
| AARSD1 | alanyl-tRNA synthetase domain containing 1 |
| ABHD17B | abhydrolase domain containing 17B |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| ALPK1 | alpha-kinase 1 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATP11B | ATPase, class VI, type 11B |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BMP4 | bone morphogenetic protein 4 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| C5AR2 | complement component 5a receptor 2 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CCDC186 | coiled-coil domain containing 186 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CD82 | CD82 molecule |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CORT | cortistatin |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CTAGE9 | CTAGE family, member 9 |
| DCAF10 | DDB1 and CUL4 associated factor 10 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DRD1 | dopamine receptor D1 |
| DSPP | dentin sialophosphoprotein |
| EAF2 | ELL associated factor 2 |
| ERCC4 | excision repair cross-complementation group 4 |
| FAM131A | family with sequence similarity 131, member A |
| FHOD1 | formin homology 2 domain containing 1 |
| FLCN | folliculin |
| FRK | fyn-related Src family tyrosine kinase |
| FUZ | fuzzy planar cell polarity protein |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GPR19 | G protein-coupled receptor 19 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIST1H4F | histone cluster 1, H4f |
| HIST1H4J | histone cluster 1, H4j |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| IFT140 | intraflagellar transport 140 |
| IGSF1 | immunoglobulin superfamily, member 1 |
| IL15RA | interleukin 15 receptor, alpha |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| ITPKC | inositol-trisphosphate 3-kinase C |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KIAA0894 | KIAA0894 protein |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| KLHL26 | kelch-like family member 26 |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LINS | lines homolog (Drosophila) |
| LOC100287590 | uncharacterized LOC100287590 |
| MAGEF1 | melanoma antigen family F1 |
| MAP9 | microtubule-associated protein 9 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| NAG18 | NAG18 mRNA |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| NLK | nemo-like kinase |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PCDHA5 | protocadherin alpha 5 |
| PDE8B | phosphodiesterase 8B |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLXND1 | plexin D1 |
| PMM1 | phosphomannomutase 1 |
| POLH | polymerase (DNA directed), eta |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRSS22 | protease, serine, 22 |
| RAD51AP1 | RAD51 associated protein 1 |
| RPGR | retinitis pigmentosa GTPase regulator |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SIK1 | salt-inducible kinase 1 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TLN1 | talin 1 |
| TNS2 | tensin 2 |
| TRABD | TraB domain containing |
| TRIM16 | tripartite motif containing 16 |
| TTBK2 | tau tubulin kinase 2 |
| TUBA3C | tubulin, alpha 3c |
| USP36 | ubiquitin specific peptidase 36 |
| WFDC2 | WAP four-disulfide core domain 2 |
| ZNF329 | zinc finger protein 329 |
| ZNF35 | zinc finger protein 35 |
| ZNF430 | zinc finger protein 430 |
| ZNF574 | zinc finger protein 574 |
| ZNF652 | zinc finger protein 652 |
| ZNF778 | zinc finger protein 778 |
