| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the imipenem-7294 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ADAM17 | ADAM metallopeptidase domain 17 |
| ADAP2 | ArfGAP with dual PH domains 2 |
| AK1 | adenylate kinase 1 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| AP1M2 | adaptor-related protein complex 1, mu 2 subunit |
| ARHGAP26 | Rho GTPase activating protein 26 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 |
| AURKA | aurora kinase A |
| BCL6 | B-cell CLL/lymphoma 6 |
| BICD1 | bicaudal D homolog 1 (Drosophila) |
| BIRC3 | baculoviral IAP repeat containing 3 |
| C6ORF10 | chromosome 6 open reading frame 10 |
| CA9 | carbonic anhydrase IX |
| CCNG2 | cyclin G2 |
| CCR2 | chemokine (C-C motif) receptor 2 |
| CD4 | CD4 molecule |
| CDK13 | cyclin-dependent kinase 13 |
| CEP162 | centrosomal protein 162kDa |
| CISH | cytokine inducible SH2-containing protein |
| CNPPD1 | cyclin Pas1/PHO80 domain containing 1 |
| COL3A1 | collagen, type III, alpha 1 |
| COL7A1 | collagen, type VII, alpha 1 |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CUL7 | cullin 7 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 |
| CYHR1 | cysteine/histidine-rich 1 |
| DTNA | dystrobrevin, alpha |
| DTX3 | deltex 3, E3 ubiquitin ligase |
| DUSP8 | dual specificity phosphatase 8 |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| EIF3M | eukaryotic translation initiation factor 3, subunit M |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| ETV6 | ets variant 6 |
| FGF5 | fibroblast growth factor 5 |
| FLJ11292 | |
| GOLGA2 | golgin A2 |
| GPC1 | glypican 1 |
| GPR17 | G protein-coupled receptor 17 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIH1 | interferon induced with helicase C domain 1 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IFT27 | intraflagellar transport 27 |
| IPO8 | importin 8 |
| KAZN | kazrin, periplakin interacting protein |
| KHK | ketohexokinase (fructokinase) |
| KRT6B | keratin 6B, type II |
| LRP4 | low density lipoprotein receptor-related protein 4 |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MAPRE2 | microtubule-associated protein, RP/EB family, member 2 |
| MDFIC | MyoD family inhibitor domain containing |
| MEF2D | myocyte enhancer factor 2D |
| METTL7A | methyltransferase like 7A |
| MGAT2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| MX1 | MX dynamin-like GTPase 1 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| MYRF | myelin regulatory factor |
| NDE1 | nudE neurodevelopment protein 1 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| PHF20L1 | PHD finger protein 20-like 1 |
| PIP | prolactin-induced protein |
| PRKCA | protein kinase C, alpha |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| SBNO2 | strawberry notch homolog 2 (Drosophila) |
| SCG5 | secretogranin V |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SIDT2 | SID1 transmembrane family, member 2 |
| SIRT5 | sirtuin 5 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SPOCK3 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| SYT11 | synaptotagmin XI |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa |
| TCF12 | transcription factor 12 |
| THOC5 | THO complex 5 |
| TMEM63A | transmembrane protein 63A |
| TRAK1 | trafficking protein, kinesin binding 1 |
| TRANK1 | tetratricopeptide repeat and ankyrin repeat containing 1 |
| TRIO | trio Rho guanine nucleotide exchange factor |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VNN1 | vanin 1 |
| WDR25 | WD repeat domain 25 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF675 | zinc finger protein 675 |
| ZNF85 | zinc finger protein 85 |
| Symbol | Name |
|---|---|
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| AP1AR | adaptor-related protein complex 1 associated regulatory protein |
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 |
| ATAD2B | ATPase family, AAA domain containing 2B |
| ATAD3A | ATPase family, AAA domain containing 3A |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BAG4 | BCL2-associated athanogene 4 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BORA | bora, aurora kinase A activator |
| C17ORF80 | chromosome 17 open reading frame 80 |
| CAMTA2 | calmodulin binding transcription activator 2 |
| CCDC68 | coiled-coil domain containing 68 |
| CCRL2 | chemokine (C-C motif) receptor-like 2 |
| CEP72 | centrosomal protein 72kDa |
| CFAP69 | cilia and flagella associated protein 69 |
| CHST10 | carbohydrate sulfotransferase 10 |
| CINP | cyclin-dependent kinase 2 interacting protein |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 |
| DLK1 | delta-like 1 homolog (Drosophila) |
| DLK2 | delta-like 2 homolog (Drosophila) |
| EFNA3 | ephrin-A3 |
| EXOC3 | exocyst complex component 3 |
| FAM188A | family with sequence similarity 188, member A |
| FBXL4 | F-box and leucine-rich repeat protein 4 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 |
| FPGS | folylpolyglutamate synthase |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| FZD3 | frizzled class receptor 3 |
| GPATCH2L | G patch domain containing 2-like |
| HIRA | histone cell cycle regulator |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2AM | histone cluster 1, H2am |
| HMOX1 | heme oxygenase 1 |
| HSD3B2 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 |
| IL11RA | interleukin 11 receptor, alpha |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| KIAA0232 | KIAA0232 |
| KIFC1 | kinesin family member C1 |
| KIRREL | kin of IRRE like (Drosophila) |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LOC100127972 | uncharacterized LOC100127972 |
| LSR | lipolysis stimulated lipoprotein receptor |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MANBA | mannosidase, beta A, lysosomal |
| MAP1S | microtubule-associated protein 1S |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| METTL2B | methyltransferase like 2B |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MITF | microphthalmia-associated transcription factor |
| NBEAL2 | neurobeachin-like 2 |
| NDRG4 | NDRG family member 4 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 |
| ODF2 | outer dense fiber of sperm tails 2 |
| OGFRL1 | opioid growth factor receptor-like 1 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| P3H2 | prolyl 3-hydroxylase 2 |
| PDE12 | phosphodiesterase 12 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLCD1 | phospholipase C, delta 1 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| POR | P450 (cytochrome) oxidoreductase |
| RAB8B | RAB8B, member RAS oncogene family |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| REPS2 | RALBP1 associated Eps domain containing 2 |
| RPAP2 | RNA polymerase II associated protein 2 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RPS17P5 | ribosomal protein S17 pseudogene 5 |
| SCAI | suppressor of cancer cell invasion |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) |
| SECISBP2 | SECIS binding protein 2 |
| SLC22A18 | solute carrier family 22, member 18 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| SRBD1 | S1 RNA binding domain 1 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STAR | steroidogenic acute regulatory protein |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| TBC1D19 | TBC1 domain family, member 19 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TNNI3 | troponin I type 3 (cardiac) |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRMT13 | tRNA methyltransferase 13 homolog (S. cerevisiae) |
| USB1 | U6 snRNA biogenesis 1 |
| WNT7A | wingless-type MMTV integration site family, member 7A |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZNF197 | zinc finger protein 197 |
| ZNF230 | zinc finger protein 230 |
| ZNF34 | zinc finger protein 34 |
| ZNF385D | zinc finger protein 385D |